Results 71 to 80 of about 3,626,397 (167)

Investigation of plasmid-mediated quinolone resistance in Pseudomonas aeruginosa clinical isolates

, 2014
Aims: To investigate plasmid-mediated quinolone resistance in clinical isolates of Pseudomonas aeruginosa with the polymerase chain reaction (PCR).
M Gunaydin, Gunaydin, Murat, Y Tanriverdi Cayci, Coban, A. Y., CAYCI, Y. Tanriverdi, AY Coban   +5 more
core   +1 more source

Genomic Epidemiology of Multidrug‐Resistant Clinical Klebsiella pneumoniae From Pakistan

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Study design and bioinformatics workflow. Cohort selection and uniform workflow. ABSTRACT Background Antimicrobial‐resistant Klebsiella pneumoniae is a major clinical threat in Pakistan and the wider South Asian region, where genomic surveillance remains limited. We analyzed 122 publicly available human clinical K.
Hakeem Zada, Muhammad Qasim, Mubashir Hussain, Abdul Rehman, Hassan Naveed, Noor Bahadar, Najibullah Anwari   +6 more
wiley   +1 more source

Impact of co-existence of PMQR genes and QRDR mutations on fluoroquinolones resistance in Enterobacteriaceae strains isolated from community and hospital acquired UTIs

BMC Infectious Diseases, 2019
Background Fluoroquinolones are commonly recommended as treatment for urinary tract infections (UTIs). The development of resistance to these agents, particularly in gram-negative microorganisms complicates treatment of infections caused by these ...
Dalia Nabil Kotb, Wafaa Khairy Mahdy, Mahmoud Shokry Mahmoud, Rasha M. M. Khairy   +3 more
doaj   +1 more source

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, Volume 4, Issue 4, July 2026.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source

Unexpected Occurrence of Plasmid-Mediated Quinolone Resistance Determinants in Environmental Aeromonas spp.

, 2008
We searched for plasmid-mediated quinolone resistance determinants of the Qnr type in several water samples collected at diverse locations from the Seine River (Paris, France). The qnrS2 genes were identified from Aeromonas punctata subsp. punctata and A.
Laurent Poirel, Vincent Cattoir, Claude-James Soussy, Patrice Nordmann, Camille Aubert   +4 more
core   +1 more source

First report on incn plasmid-mediated quinolone resistance gene qnrS1 in porcine escherichia coli in europe

, 2011
Plasmid-mediated quinolone resistance (PMQR) of enterobacteria encoded by qnr genes is an emerging concern in human and veterinary medicine. Here we aimed to study PMQR of porcine Escherichia coli in two large piggeries in Romania and Hungary.
Szmolka, D. and Villa, Carattoli A, . and Anjum, M. F. and Nagy, A. and Fortini   +5 more
core   +1 more source

The Current Case of Quinolones: Synthetic Approaches and Antibacterial Activity

Molecules, 2016
Quinolones are broad-spectrum synthetic antibacterial drugs first obtained during the synthesis of chloroquine. Nalidixic acid, the prototype of quinolones, first became available for clinical consumption in 1962 and was used mainly for urinary tract ...
Abdul Naeem, Syed Lal Badshah, Mairman Muska, Nasir Ahmad, Khalid Khan   +4 more
doaj   +1 more source

Plasmid-Mediated Ampicillin, Quinolone, and Heavy Metal Co-Resistance among ESBL-Producing Isolates from the Yamuna River, New Delhi, India

, 2020
Antibiotic resistance is one of the major current global health crises. Because of increasing contamination with antimicrobials, pesticides, and heavy metals, the aquatic environment has become a hotspot for emergence, maintenance, and dissemination of ...
Firdoos Ahmad Gogry, Aftab Hossain Mondal, Qazi Mohd. Rizwanul Haq, Mohammad Tahir Siddiqui, Fohad Mabood Husain, Ali Alsalme   +5 more
core   +1 more source

PLASMID-MEDIATED QUINOLONE RESISTANCE – PMQR [PDF]

Postępy Mikrobiologii, 2018
Katarzyna Piekarska
doaj   +1 more source

Genetic markers associated with resistance to beta-lactam and quinolone antimicrobials in non-typhoidal Salmonella isolates from humans and animals in central Ethiopia

Antimicrobial Resistance and Infection Control, 2017
Background Beta-lactam and quinolone antimicrobials are commonly used for treatment of infections caused by non-typhoidal Salmonella (NTS) and other pathogens. Resistance to these classes of antimicrobials has increased significantly in the recent years.
Tadesse Eguale, Josephine Birungi, Daniel Asrat, Moses N. Njahira, Joyce Njuguna, Wondwossen A. Gebreyes, John S. Gunn, Appolinaire Djikeng, Ephrem Engidawork   +8 more
doaj   +1 more source