Results 131 to 140 of about 1,194,207 (363)

Identification of dfrA14 in two distinct plasmids conferring trimethoprim resistance in Actinobacillus pleuropneumoniae. [PDF]

, 2015
OBJECTIVES: The objective of this study was to determine the distribution and genetic basis of trimethoprim resistance in Actinobacillus pleuropneumoniae isolates from pigs in England.
Holden, MTG, Atherton, Tom, Rogers, Jon, Maskell, Duncan J, Chaudhuri, RR, Tucker, AW, Rycroft, Andrew N, Rycroft, AN, Walker, S, Tucker, A W, Weinert, LA, Weinert, Lucy A, Wren, Brendan W, Atherton, T, Bossé, J T, BRaDP1T Consortium, Chaudhuri, R R, Bossé, Janine T, Tucker, Alexander W, Chaudhuri, Roy R, Oshota, Olusegun, Walker, Stephanie, Langford, PR, Crespo, R F, Rogers, J, Rycroft, A N, Oshota, O, Fernandez Crespo, R, Wren, BW, Fernandez Crespo, Roberto, Holden, M T G, Williamson, Susanna M, Williamson, S M, Maskell, D J, Wren, B W, Williamson, SM, Weinert, L A, Li, Yanwen, Langford, P R, Maskell, DJ, Langford, Paul R, Holden, Matthew, Li, Y, Holden, Matt TG, Bosse, J   +44 more
core   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Analysis of copy number variations of the plasmid of various yeast clades

, 2022
The goal was to know the number of plasmid copies in different yeast clades and the difference between them.Biochemical EngineeringBSc ...
Musa, Asmau
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Plasmid-mediated restriction evasion mechanisms

, 1999
Plasmid ColIb-P9 (Incll) encodes mechanisms which allow it to avoid destruction by type I and type II restriction enzymes during transfer by conjugation between strains of Escherichia coli. A genetic system was developed to analyse these mechanisms.
Nicola Jayne. Althorpe (7679351)
core  

Escherichia coli of sequence type 3835 carrying blaNDM-1, blaCTX-M-15, blaCMY-42 and blaSHV-12

, 2015
New Delhi metallo-β-lactamase (NDM) represents a serious challenge for treatment and public health. A carbapenem-resistant Escherichia coli clinical strain WCHEC13-8 was subjected to antimicrobial susceptibility tests, whole genome sequencing and ...
Wang, X, Zong, Z, Yang, Ping, Xie, Y, Zong, Zhiyong, Feng, Yu, Yang, P, Feng, Y, McNally, A, Wang, Xiaohui, McNally, Alan; id_orcid, Xie, Yi   +11 more
core   +1 more source

DNA vaccines for viral diseases

Brazilian Journal of Medical and Biological Research, 1999
DNA plasmids encoding foreign proteins may be used as immunogens by direct intramuscular injection alone, or with various adjuvants and excipients, or by delivery of DNA-coated gold particles to the epidermis through biolistic immunization.
J.J. Donnelly, J.B. Ulmer
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Complete Sequence of Plasmid pLH1 from Lactobacillus helveticus ATCC15009: Analysis Reveals the Presence of Regions Homologous to Other Native Plasmids from the Host Strain

, 1999
The complete sequence for plasmid pLH1 from Lactobacillus helveticus ATCC15009 has beendetermined. Analysis of the 19,360-bp primary sequence revealed a putative replication origin andinitiation protein, information that could provide the basis for the ...
McConville, K J, Thompson, J K, Nicholson, C, Collins, M A, Pridmore, R D, Foley, Sophie   +5 more
core   +1 more source

Plasmid-Encoded Outer Membrane Protein YadA Mediates Specific Binding of Enteropathogenic Yersiniae to Various Types of Collagen [PDF]

, 1992
The plasmid-encoded outer membrane protein YadA of enteropathogenic yersiniae is associated with pathogenicity. Recently, collagen binding of YadA-positive yersiniae was reported without detailed characterization (L. Emödy, J. Heesemann, H. Wolf-Watz, M.
Emmerich, F., Burkhardt, H., Schulze-Koops, Hendrik, Heesemann, Jürgen, Mark, K. von der   +4 more
core   +1 more source