Results 11 to 20 of about 1,044,031 (345)
Fitness Costs of Plasmids: a Limit to Plasmid Transmission [PDF]
Microbiology Spectrum, 2017 ABSTRACT Plasmids mediate the horizontal transmission of genetic information between bacteria, facilitating their adaptation to multiple environmental conditions. An especially important example of the ability of plasmids to catalyze bacterial adaptation and evolution is their instrumental role in the global spread of antibiotic resistance ...
San Millan, A, Maclean, R
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Plasmid persistence: costs, benefits, and the plasmid paradox [PDF]
Canadian Journal of Microbiology, 2018 Plasmids are extrachromosomal DNA elements that can be found throughout bacteria, as well as in other domains of life. Nonetheless, the evolutionary processes underlying the persistence of plasmids are incompletely understood. Bacterial plasmids may encode genes for traits that are sometimes beneficial to their hosts, such as antimicrobial resistance,
Carroll, Amanda C., Wong, Alex
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Variability of plasmid fitness effects contributes to plasmid persistence in bacterial communities
Nature Communications, 2021 Plasmid persistence in bacterial populations is strongly influenced by the fitness effects associated with plasmid carriage. However, plasmid fitness effects in wild-type bacterial hosts remain largely unexplored. In this study, we determined the fitness
Aida Alonso-del Valle +8 more
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Nucleic Acids Research, 2021 Plasmids and temperate phages are key contributors to bacterial evolution. They are usually regarded as very distinct. However, some elements, termed phage–plasmids, are known to be both plasmids and phages, e.g. P1, N15 or SSU5. The number, distribution,
E. Pfeifer +3 more
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Frontiers in Microbiology, 2022 Salmonella enterica serotype Indiana (S. Indiana) in Chinese poultry meat has aroused widespread concern because of its high prevalence and strong antimicrobial resistance. In consideration of the relationship in our previous study between S. Indiana and
Yujie Hu +15 more
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Microbiology Spectrum, 2023 Mobile colistin resistance (mcr) genes are present mainly in plasmids and can disseminate clonally or horizontally via either plasmids or insertion sequences in different genomic locations among the Enterobacteriaceae.
Tingting Yang +13 more
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Detection of an IMI-2 carbapenemase-producing Enterobacter asburiae at a Swedish feed mill
Frontiers in Microbiology, 2022 Occurrence of multidrug resistant Enterobacteriaceae in livestock is of concern as they can spread to humans. A potential introduction route for these bacteria to livestock could be animal feed.
Stefan Börjesson +8 more
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DNA Minicircle Technology Improves Purity of Adeno-associated Viral Vector Preparations
Molecular Therapy: Nucleic Acids, 2016 Adeno-associated viral (AAV) vectors are considered as one of the most promising delivery systems in human gene therapy. In addition, AAV vectors are frequently applied tools in preclinical and basic research. Despite this success, manufacturing pure AAV
Maria Schnödt +9 more
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Microbiology Spectrum, 2022 Dissemination of blaNDM, which is carried on the IncX3 plasmid, among Enterobacterales has been reported worldwide. In particular, blaNDM-5-carrying IncX3 plasmids can spread among several hosts, facilitating their dissemination.
Tsukasa Ariyoshi +5 more
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A rapid alkaline extraction procedure for screening recombinant plasmid DNA.
Nucleic Acids Research, 1979 A procedure for extracting plasmid DNA from bacterial cells is described. The method is simple enough to permit the analysis by gel electrophoresis of 100 or more clones per day yet yields plasmid DNA which is pure enough to be digestible by restriction ...
H. Birnboim, J. Doly
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