Results 31 to 40 of about 1,085,040 (311)

Molecular Characterization and Comparative Genomics of IncQ-3 Plasmids Conferring Resistance to Various Antibiotics Isolated from a Wastewater Treatment Plant in Warsaw (Poland)

Antibiotics, 2020
As small, mobilizable replicons with a broad host range, IncQ plasmids are widely distributed among clinical and environmental bacteria. They carry antibiotic resistance genes, and it has been shown that they confer resistance to β-lactams ...
Marta Piotrowska, Lukasz Dziewit, Rafał Ostrowski, Cora Chmielowska, Magdalena Popowska   +4 more
doaj   +1 more source

The rise and spread of mcr plasmid-mediated polymyxin resistance

Critical reviews in microbiology, 2019
Polymyxins are important lipopeptide antibiotics that serve as the last-line defense against multidrug-resistant (MDR) Gram-negative bacterial infections. Worryingly, the clinical utility of polymyxins is currently facing a serious threat with the global
Sue C Nang, J. Li, T. Velkov
semanticscholar   +1 more source

Carbapenemases: Transforming Acinetobacter baumannii into a Yet More Dangerous Menace

Biomolecules, 2020
Acinetobacter baumannii is a common cause of serious nosocomial infections. Although community-acquired infections are observed, the vast majority occur in people with preexisting comorbidities. A. baumannii emerged as a problematic pathogen in the 1980s
Maria Soledad Ramirez, Robert A. Bonomo, Marcelo E. Tolmasky   +2 more
doaj   +1 more source

Enhancing student understanding of genetic cloning through a 3D-printed active learning activity and flipped classroom curriculum

Journal of Microbiology & Biology Education
This classroom curriculum is designed to teach the topic of cloning in both small- and large-enrollment undergraduate general microbiology courses. Students often struggle to grasp and visualize genetic engineering or cloning, in which a piece of DNA is ...
Katriana A. Popichak, Kathryn Krupinsky, Delaney Worthington, Samuel Fredricks, Leila Takahashi-Ruiz, Mary Howerton, Marcela Henao-Tamayo, Erica L. Suchman, Jennifer L. McLean   +8 more
doaj   +1 more source

Plasmid-driven clonal expansion of multidrug-resistant monophasic Salmonella Typhimurium in a Global Food Trade Hub

Emerging Microbes and Infections
Shenzhen, a major port city with a heavily imported food supply, offers a critical setting to examine the spread and adaptation of multidrug-resistant Salmonella 1,4,[5],12:i: – (S. 1,4,[5],12:i:-).
Dingjie Huang, Ziqi Wu, Yixiang Jiang, Lulu Hu, Rui Cai, Xi Yang, Chen Du, Shiting Chen, Panpan Yang, Bingchan Guo, Xiaolu Shi, Shuang Wu, Yinghui Li, Zhemin Zhou, Qinghua Hu   +14 more
doaj   +1 more source

Plasmid evolution in carbapenemase‐producing Enterobacteriaceae: a review

Annals of the New York Academy of Sciences, 2019
Carbapenem‐resistant Enterobacteriaceae (CRE) have been listed by the WHO as high‐priority pathogens owing to their high association with mortalities and morbidities.
K. Kopotsa, John Osei Sekyere, N. Mbelle
semanticscholar   +1 more source

Characterization of a novel Phietavirus genus bacteriophage and its potential for efficient transfer of modified shuttle plasmids to Staphylococcus aureus strains of different clonal complexes

Microbiology Spectrum
Staphylococcus aureus is a significant human pathogen responsible for various nosocomial and community-acquired infections, leading to considerable morbidity and mortality worldwide. Temperate bacteriophages contribute to its virulence and facilitate the
Łukasz Kałuski, Emil Stefańczyk, Aleksandra Głowacka-Rutkowska, Jan Gawor, Joanna Empel, Monika Orczykowska-Kotyna, Aleksandra Szczypkowska, Karolina Żuchniewicz, Robert Gromadka, Małgorzata Łobocka   +9 more
doaj   +1 more source

KPC-2-Producing Carbapenem-Resistant Klebsiella pneumoniae of the Uncommon ST29 Type Carrying OXA-926, a Novel Narrow-Spectrum OXA β-Lactamase

Frontiers in Microbiology, 2021
We isolated and characterized a carbapenem-resistant Klebsiella pneumoniae (CRKP) clinical strain from blood carrying a novel blaOXA gene, blaOXA–926, and belonging to ST29, an uncommon CRKP type. The strain, 130002, was genome sequenced using both short-
Lina Liu, Yu Feng, Li Wei, Yuling Xiao, Zhiyong Zong, Zhiyong Zong, Zhiyong Zong, Zhiyong Zong   +7 more
doaj   +1 more source

Fitness Costs of Plasmids: a Limit to Plasmid Transmission

Microbiology spectrum, 2017
Plasmids mediate the horizontal transmission of genetic information between bacteria, facilitating their adaptation to multiple environmental conditions.
Á. S. Millán, R. MacLean, Fernando Baquero, T. Coque, Á. S. Millán   +4 more
semanticscholar   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source