Results 41 to 50 of about 1,044,031 (345)
Fitness Advantage of mcr-1–Bearing IncI2 and IncX4 Plasmids in Vitro
The objective of this study was to assess the impact of diverse plasmids bearing colistin resistance gene mcr-1 on host fitness. Forty-seven commensal E.
Renjie Wu+8 more
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IncHI2 ST3 plasmids are known carriers of multiple antimicrobial resistance genes. Complete plasmid sequences from multiple drug resistant Escherichia coli circulating in Australian swine is however limited.
Ethan R. Wyrsch+7 more
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Antiparallel plasmid-plasmid pairing may control P1 plasmid replication. [PDF]
The copy number of the P1 plasmid replicon is stringently controlled, giving only one or two copies per newborn cell. Control is achieved by the action of the copy-control locus incA, which contains nine repeats of the 19-basepair binding site for the plasmid-encoded initiator protein RepA.
Ann L. Abeles, Stuart Austin
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A Comparison of Plasmid DNA and mRNA as Vaccine Technologies
This review provides a comparison of the theoretical issues and experimental findings for plasmid DNA and mRNA vaccine technologies. While both have been under development since the 1990s, in recent years, significant excitement has turned to mRNA ...
Margaret A. Liu
semanticscholar +1 more source
Plasmids in Rhizobia: The Role of Nonsymbiotic Plasmids
Peer ...
Mercado-Blanco, Jesús, Toro, Nicolás
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Exploiting CRISPR-Cas to manipulate Enterococcus faecalis populations
CRISPR-Cas provides a barrier to horizontal gene transfer in prokaryotes. It was previously observed that functional CRISPR-Cas systems are absent from multidrug-resistant (MDR) Enterococcus faecalis, which only possess an orphan CRISPR locus, termed ...
Karthik Hullahalli+2 more
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Klebsiella pneumoniae exhibits extensive phenotypic and genetic diversity. Higher plasmid loads in the cell were supposed to play an key role in its genome diversity.
Mufeng Cai+23 more
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Microorganisms have developed many strategies in the process of long-term defense against external attacks, one of which is the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated proteins (Cas) bacterial immunological ...
Yuqiao Zhou+10 more
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Plasmid evolution in carbapenemase‐producing Enterobacteriaceae: a review
Carbapenem‐resistant Enterobacteriaceae (CRE) have been listed by the WHO as high‐priority pathogens owing to their high association with mortalities and morbidities.
K. Kopotsa, John Osei Sekyere, N. Mbelle
semanticscholar +1 more source
The gossip paradox: Why do bacteria share genes?
Bacteria, in contrast to eukaryotic cells, contain two types of genes: chromosomal genes that are fixed to the cell, and plasmids, smaller loops of DNA capable of being passed from one cell to another.
Alastair D. Jamieson-Lane, Bernd Blasius
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