Results 171 to 180 of about 741,058 (313)

Biogenesis of Organelles and Membrane Proteins. [PDF]

open access: yes, 1988
Harmey, Matthew A.   +3 more
core   +1 more source

Genetic Control of Tissue Remodeling by a Non‐Coding SNP in ITGA8 Explains Carotenoid‐Based Color Polymorphism in Marine Mollusks

open access: yesAdvanced Science, EarlyView.
In this study, the orange‐muscle giant abalone (Haliotis gigantea) is used as a model to identify a non‐coding SNP that disrupts the interaction between ITGA8 pre‐mRNA and the splicing factor ILF2, leading to altered ITGA8 splicing. These splicing changes promote carotenoid accumulation in abalone muscle through the regulation of tissue remodeling ...
Xiaohui Wei   +17 more
wiley   +1 more source

Mechanical Strain‐Programmed SDC1+ Sheath Fibroblasts Trigger CXCR4hi Neutrophil‐Mediated Enthesitis in Ankylosing Spondylitis

open access: yesAdvanced Science, EarlyView.
In ankylosing spondylitis (AS), mechanical strain‐programmed SDC1+ sheath fibroblasts secrete CXCL5 to recruit neutrophils and promote the activation of CXCR4hi neutrophils, thereby exacerbating enthesitis by promoting neutrophil extracellular traps (NETs) formation. SOX5 controls the generation of SDC1+ sheath fibroblasts via super‐enhancers.
Jiajie Lin   +13 more
wiley   +1 more source

Molecular basis of ParA ATPase activation by the CTPase ParB during bacterial chromosome segregation. [PDF]

open access: yesNat Commun
Schnabel L   +10 more
europepmc   +2 more sources

Targeting DAP5 Disrupts Alternate Mode of Translational Initiation in Tregs and Potentiates Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
Regulatory T cells (Tregs) suppress antitumor immunity. This study identifies that the translation scaffold DAP5/eIF4G2 is upregulated in tumor‐infiltrating Tregs (ti‐Tregs). DAP5 mediates an alternate translation mode to sustain CD25 and MCL‐1 expression, which is critical for ti‐Treg stability and survival in the tumor microenvironment.
Xiaojiang Lai   +12 more
wiley   +1 more source

A Plasmid Partition System of the P1-P7par Family from the pMT1 Virulence Plasmid ofYersinia pestis

open access: yesJournal of Bacteriology, 2000
Brenda Youngren   +4 more
semanticscholar   +1 more source

Remote Activation of Spinal TRPV1 by Magnetic Nanocubes Confers Cardioprotection Against Myocardial Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
Fe‐based magnetic nanocubes conjugated with TRPV1 antibodies (FeNCs‐TRPV1) are developed for the specific targeting of TRPV1 channels. Intraspinally injected FeNCs‐TRPV1 induces TRPV1 desensitization in rats exposed to repetitive and transient ACMF.
Xueying Cheng   +15 more
wiley   +1 more source

Plasmid Partition System of the P1par Family from the pWR100 Virulence Plasmid of Shigella flexneri

open access: yesJournal of Bacteriology, 2005
Kirill V. Sergueev   +2 more
semanticscholar   +1 more source

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