Results 41 to 50 of about 741,058 (313)
Sequence analysis of pKF3-70 in Klebsiella pneumoniae: probable origin from R100-like plasmid of Escherichia coli. [PDF]
PLoS ONE, 2010 BACKGROUND: Klebsiella pneumoniae is a clinically significant species of bacterium which causes a variety of diseases. Clinical treatment of this bacterial infection is greatly hindered by the emergence of multidrug-resistant strains.
Huiguang Yi +14 more
doaj +1 more source
Partition of plasmid DNA in polymer-salt aqueous two phase systems [PDF]
, 2009 The partition of plasmid DNA (pDNA) in polyethylene glycol (PEG)–phosphate aqueous two-phase systems (ATPS) is presented. A high molecular weight (HMW) and a low molecular weight (LMW) polymer, PEG-1450 and -300, were used in combination with di ...
Luechau, Frank +2 more
core +1 more source
The Plasmid Mobilome of the Model Plant-Symbiont Sinorhizobium meliloti: Coming up with New Questions and Answers [PDF]
, 2014 Rhizobia are Gram-negative Alpha- andBetaproteobacteria living in the underground that have theability to associate with legumes for the establishment ofnitrogen-fixing symbioses.Sinorhizobium melilotiinparticular—the symbiont ofMedicago,Melilotus ...
Lagares, Antonio +2 more
core +2 more sources
Plasmid Interactions Can Improve Plasmid Persistence in Bacterial Populations
Frontiers in Microbiology, 2020 It is difficult to understand plasmid maintenance in the absence of selection and theoretical models predict the conditions for plasmid persistence to be limited.
João Alves Gama +3 more
doaj +1 more source
ParAB Partition Dynamics in Firmicutes: Nucleoid Bound ParA Captures and Tethers ParB-Plasmid Complexes. [PDF]
PLoS ONE, 2015 In Firmicutes, small homodimeric ParA-like (δ2) and ParB-like (ω2) proteins, in concert with cis-acting plasmid-borne parS and the host chromosome, secure stable plasmid inheritance in a growing bacterial population.
Virginia S Lioy +5 more
doaj +1 more source
Life, 2021 Gene therapy and DNA vaccination are among the most expected biotechnological and medical advances for the coming years. However, the lack of cost-effective large-scale production and purification of pharmaceutical-grade plasmid DNA (pDNA) still hampers ...
Nuno R. da Silva +4 more
doaj +1 more source
Probing plasmid partition with centromere‐based incompatibility [PDF]
Molecular Microbiology, 2004 SummaryLow‐copy number plasmids of bacteria rely on specific centromeres for regular partition into daughter cells. When also present on a second plasmid, the centromere can render the two plasmids incompatible, disrupting partition and causing plasmid loss. We have investigated the basis of incompatibility exerted by the F plasmid centromere, sopC, to
Jean-Yves, Bouet +4 more
openaire +2 more sources
Plasmid and chromosome partitioning: surprises from phylogeny [PDF]
Molecular Microbiology, 2000 Plasmids encode partitioning genes (par) that are required for faithful plasmid segregation at cell division. Initially, par loci were identified on plasmids, but more recently they were also found on bacterial chromosomes. We present here a phylogenetic analysis of par loci from plasmids and chromosomes from prokaryotic organisms.
Gerdes K, Møller-Jensen J, Jensen RB
openaire +4 more sources
A conserved mechanism drives partition complex assembly on bacterial chromosomes and plasmids
Molecular Systems Biology, 2018 Chromosome and plasmid segregation in bacteria are mostly driven by ParABS systems. These DNA partitioning machineries rely on large nucleoprotein complexes assembled on centromere sites (parS).
Roxanne E Debaugny +11 more
doaj +1 more source
PLoS ONE, 2012 This study characterizes the 21.4 kilobase plasmid pECTm80 isolated from Escherichia coli strain 80, an α hemolytic human clinical diarrhoeal isolate (serotype O108:H-).
Fay E Dawes +6 more
doaj +1 more source