Results 51 to 60 of about 8,687 (214)

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

FEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga, Kazuki Harada, Takuya Yamauchi, Tetsuya Kitaguchi, Masami Yokota Hirai, Mitsuharu Matsumoto, Takashi Tsuboi   +6 more
wiley   +1 more source

Antimicrobial Resistance Genes, Cassettes, and Plasmids Present in Salmonella enterica Associated With United States Food Animals

Frontiers in Microbiology, 2019
The ability of antimicrobial resistance (AR) to transfer, on mobile genetic elements (MGEs) between bacteria, can cause the rapid establishment of multidrug resistance (MDR) in bacteria from animals, thus creating a foodborne risk to human health.
Elizabeth A. McMillan, Sushim K. Gupta, Laura E. Williams, Thomas Jové, Lari M. Hiott, Tiffanie A. Woodley, John B. Barrett, Charlene R. Jackson, Jamie L. Wasilenko, Mustafa Simmons, Glenn E. Tillman, Michael McClelland, Jonathan G. Frye   +12 more
doaj   +1 more source

Multiple Plasmid Vectors Mediate the Spread of fosA3 in Extended-Spectrum-β-Lactamase-Producing Enterobacterales Isolates from Retail Vegetables in China

mSphere, 2020
The plasmid-mediated fosfomycin resistance gene fosA3 has been detected in Enterobacterales from various sources but has rarely been reported in vegetables.
Luchao Lv, Xiuyu Huang, Jing Wang, Ying Huang, Xun Gao, Yiyun Liu, Qiaoli Zhou, Qianhui Zhang, Jun Yang, Jian-Ying Guo, Jian-Hua Liu   +10 more
doaj   +1 more source

Antibiotic Resistance Mediated by Escherichia coli in Kuwait Marine Environment as Revealed through Genomic Analysis

Antibiotics, 2023
Antibiotic-resistance gene elements (ARGEs) such as antibiotic-resistance genes (ARGs), integrons, and plasmids are key to the spread of antimicrobial resistance (AMR) in marine environments.
Hanan A. Al-Sarawi, Nazima Habibi, Saif Uddin, Awadhesh N. Jha, Mohammed A. Al-Sarawi, Brett P. Lyons   +5 more
doaj   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source

Recovering Escherichia coli Plasmids in the Absence of Long-Read Sequencing Data

Microorganisms, 2021
The incidence of infections caused by multidrug-resistant E. coli strains has risen in the past years. Antibiotic resistance in E. coli is often mediated by acquisition and maintenance of plasmids. The study of E.
Julian A. Paganini, Nienke L. Plantinga, Sergio Arredondo-Alonso, Rob J. L. Willems, Anita C. Schürch   +4 more
doaj   +1 more source

A hybrid plasmid formed by recombination of a virulence plasmid and a resistance plasmid in Klebsiella pneumoniae

Journal of Global Antimicrobial Resistance, 2020
The emergence of multidrug-resistant (MDR) and hypervirulent Klebsiella pneumoniae (hvKP) facilitates simultaneous dissemination of virulence and resistance in a single event, which poses serious threat to public health.This study characterized the multidrug-resistant and moderately virulent ST11 K64 K.
Xuemei Yang, Kaichao Chen, Edward Wai-Chi Chan, Lianwei Ye, Rong Zhang, Miaomiao Xie, Ning Dong, Sheng Chen, Sheng Chen   +8 more
openaire   +4 more sources

Unconventional mRNA processing and degradation pathways for the polycistronic yrzI (spyTA) mRNA in Bacillus subtilis

FEBS Letters, EarlyView.
The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet, Magali Leroy, Alexandre Maes, Ciarán Condon, Frédérique Braun   +4 more
wiley   +1 more source

Construction of a recombinant plasmid pSH-G containing the rabies-virus glycoprotein G gene

Journal of Venomous Animals and Toxins including Tropical Diseases, 2007
A plasmid named pSH-G was constructed with the rabies-virus G-gene insert. This plasmid was transfected into eukaryotic BHK-21 cells and its stability tested.
P. Carnieli JR, A. M. Ventura, E. L. Durigon   +2 more
doaj   +1 more source

Dissection of Highly Prevalent qnrS1-Carrying IncX Plasmid Types in Commensal Escherichia coli from German Food and Livestock

Antibiotics, 2021
Plasmids are mobile genetic elements, contributing to the spread of resistance determinants by horizontal gene transfer. Plasmid-mediated quinolone resistances (PMQRs) are important determinants able to decrease the antimicrobial susceptibility of ...
Katharina Juraschek, Annemarie Käsbohrer, Burkhard Malorny, Stefan Schwarz, Diana Meemken, Jens André Hammerl   +5 more
doaj   +1 more source