Results 121 to 130 of about 234,694 (355)

Activation of Plasminogen by Trypsin and Plasmin [PDF]

, 1952
Walter Kocholaty, William W. Ellis, H. Jensen   +2 more
openalex   +1 more source

Neutralizing the EGF receptor in glioblastoma cells stimulates cell migration by activating uPAR-initiated cell signaling. [PDF]

, 2015
In glioblastoma (GBM), the EGF receptor (EGFR) and Src family kinases (SFKs) contribute to an aggressive phenotype. EGFR may be targeted therapeutically; however, resistance to EGFR-targeting drugs such as Erlotinib and Gefitinib develops quickly.
Cavenee, WK, Furnari, FB, Gonias, SL, Hu, J, Muller, KA, VandenBerg, SR   +5 more
core  

The measurement of the components of the plasminogen–plasmin system in biological fluids [PDF]

, 1954
Anthony P. Fletcher
openalex   +1 more source

Research progress of neurovascular units involved in ischemic stroke

Ibrain, EarlyView.
The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang, Hao Tong, Zhuo‐Fan Ye, Zu‐Cai Xu, Tao Tao   +4 more
wiley   +1 more source

Editor's choice : European Society for Vascular Surgery (ESVS) 2020 clinical practice guidelines on the management of acute limb ischaemia

, 2020
A
Acosta, Stefan, Azuma, Nobuyoshi, Bastos Gonçalves, Frederico, Björck, Martin, Boyle, Jonathan R., Chakfé, Nabil, Choke, Edward T. C., Cochennec, Frederic, Cohnert, Tina U., de Borst, Gert J., Document Reviewers, Earnshaw, Jonothan J., ESVS Guidelines Committee, Fitridge, Robert A., Forbes, Thomas L., Hamady, Mohamad S., Hinchliffe, Robert, Jongkind, Vincent, Kakkos, Stavros K., Koelemay, Mark J. W., Koncar, Igor, Lindholt, Jes S., Mani, Kevin, Menyhei, Gabor, Munoz, Alberto, Müller-Hülsbeck, Stefan, Rai, Kumud, Sebastian Debus, E., Svetlikov, Alexei V., Tshomba, Yamume, Tulamo, Riikka, van den Berg, Jos C., Vega de Ceniga, Melina, Vermassen, Frank   +33 more
core   +2 more sources

Effects of SADS‐CoV accessory proteins NS3a, NS7a, and NS7b on viral pathogenicity: A multi‐omics investigation

iMetaOmics, EarlyView.
This study has elucidated the role of three swine acute diarrhea syndrome coronavirus (SADS‐CoV) accessory proteins in influencing viral pathogenicity and preliminarily explored the host molecular targets and pathways affected by the NS3a, NS7a, and NS7b proteins of SADS‐CoV.
Xiaoling Yan, Xiaoli Zhang, Ling Zhou, Xiaoya Zhao, Qianniu Li, Tian Lan, Jun Fu, Jingyun Ma   +7 more
wiley   +1 more source

GENERATION OF CHEMOTACTIC ACTIVITY IN RABBIT SERUM BY PLASMINOGEN-STREPTOKINASE MIXTURES [PDF]

, 1967
Fletcher B. Taylor, Peter A. Ward
openalex   +1 more source

Evaluating Tranexamic Acid Dosing Strategies for Postpartum Hemorrhage: A Population Pharmacokinetic Approach in Pregnant Individuals

The Journal of Clinical Pharmacology, EarlyView.
Abstract Tranexamic acid (TXA) is used for the treatment and occasionally prevention of postpartum hemorrhage (PPH); however, questions still remain regarding dosing regimen optimization. This study evaluated TXA pharmacokinetic (PK) data from four clinical trials (NCT: 04274335, 03287336, 00872469, and 02797119) conducted in pregnant participants ...
Allison Dunn, Mina Felfeli, Sebastian M. Seifert, Sixtine Gilliot, Anne‐Sophie Ducloy‐Bouthors, Haleem Shakur‐Still, Amber Geer, Stanislas Grassin‐Delyle, Naomi L. Luban, Johannes N. van den Anker, Jogarao V. S. Gobburu, Ian Roberts, Homa K. Ahmadzia   +12 more
wiley   +1 more source

Four Pharmacogenomic Variants Strongly Linked to Corticosteroid‐Induced Avascular Necrosis in Children with Cancer

The Journal of Clinical Pharmacology, EarlyView.
Abstract Corticosteroids are effective anti‐cancer agents for treating hematologic malignancies in children. However, avascular necrosis (AVN) is a common and debilitating adverse effect, leading to bone death and impacting long‐term quality of life. This study aimed to uncover the genetic factors contributing to corticosteroid‐induced AVN in a well ...
Miguel Cordova‐Delgado, Erika N. Scott, Shahrad R. Rassekh, Catrina M. Loucks, Wan‐Chun Chang, Edward J. Raack, Jessica N. Trueman, Colin J. D. Ross, Bruce C. Carleton, the Canadian Pharmacogenomics Network for Drug Safety Consortium   +9 more
wiley   +1 more source

Abnormal Plasminogen-Plasmin System Activity (Fibrinolysis) in Patients with Hepatic Cirrhosis: Its Cause and Consequences* [PDF]

, 1964
Anthony P. Fletcher, Oliver Biederman, Don Moore, Norma Alkjærsig, Sol Sherry   +4 more
openalex   +1 more source