Results 131 to 140 of about 207,129 (257)

Role of the Plasminogen Activation System in Liver Injury and Repair: Knowns and Known Unknowns. [PDF]

Arterioscler Thromb Vasc Biol
Banerjee D, Wei Z, Luyendyk JP.
europepmc   +1 more source

Senolytics and exercise: Dual modalities for rejuvenating muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican, Ce Qi, Uchenna Okpechi, Maya Strand Ford, Georgina M. Ellison‐Hughes   +4 more
wiley   +1 more source

Beyond Direct Fibrinolysis: Novel Approaches to Thrombolysis. [PDF]

Pharmaceuticals (Basel)
Shibeko AM, Nikitin NS, Podoplelova NA, Manuvera VA, Lazarev VN.   +4 more
europepmc   +1 more source

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani, Haibo Ni, Jeffrey J Saucerman, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +5 more
wiley   +1 more source

Coagulation Markers and Myocardial Blush Grade in STEMI: Identifying Potential Predictors of Microvascular Reperfusion. [PDF]

Clin Appl Thromb Hemost
Doğanözü E, Çiftci O, Bal UA, Aydınalp A, Has Hasırcı S, Özin MB, Haldun Müderrisoğlu I.   +6 more
europepmc   +1 more source

Surgical management of acute choroidal neovascularization related submacular hemorrhage: Three case reports. [PDF]

World J Clin Cases
El Mollayess G, Jaroudi M, Tlaiss Y, Itaoui R, Abiad B.   +4 more
europepmc   +1 more source

Factor XIII Supplementation in Postpartum Hemorrhage: From Biological Rationale to Clinical Implementation

American Journal of Hematology, Volume 101, Issue 4, Page 794-806, April 2026.
ABSTRACT Postpartum hemorrhage (PPH) remains the leading cause of preventable maternal mortality despite standard interventions. Recent fibrinogen trials failed to improve outcomes, prompting interest in coagulation factor XIII (FXIII). FXIII functions as “molecular cement,” cross‐linking fibrin and stabilizing clots.
Jeremy W. Jacobs, Elizabeth A. Abels, Brian D. Adkins, Garrett S. Booth, Victoria Costa, Sheharyar Raza, Michelle Simon, Jennifer S. Woo, Allison P. Wheeler   +8 more
wiley   +1 more source

Serum profiling of uPA, PAI-1, and suPAR in systemic sclerosis: a preliminary study on analytical aspects and associations with microvascular and fibrotic manifestations. [PDF]

Front Immunol
Napolitano F, Mormile I, Mignogna G, de Paulis A, Rossi FW, Montuori N.   +5 more
europepmc   +1 more source

Tissue-Based Multiomic Exploratory Analysis of the Urokinase Plasminogen Activator/uPAR System and Matrix Metalloproteinases in Stroma AReactive Invasion Front Areas-Positive Gastrointestinal Cancers.

Pathobiology
Reitsam NG, Grosser B, Dintner S, Grozdanov V, Sommer F, Heyer C, Schlesner M, Hardt J, Franz S, Schenkirsch G, Probst A, Löhr P, Waidhauser J, Märkl B.   +13 more
europepmc   +1 more source

Soluble Urokinase-type Plasminogen Activator Receptor (suPAR) as a Biomarker of Neurodysfunction. [PDF]

Neuromolecular Med
de Rezende VL, Mathias K, Danielski LG, Barichello T, Petronilho F.   +4 more
europepmc   +1 more source