Results 151 to 160 of about 136,149 (288)
Enzymatic vitreolysis with recombinant tissue plasminogen activator for vitreomacular traction
Dorota Raczyńska,1 Paweł Lipowski,1 Katarzyna Zorena,2 Andrzej Skorek,3 Paulina Glasner1 1Department of Ophthalmology, Medical University of Gdańsk, Poland; 2Department of Immunobiology and Environment Microbiology, Medical University of Gdańsk, Poland;
Glasner P +4 more
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Mechanism of plasminogen activation by staphylokinase [PDF]
Staphylokinase expresses plasminogen activator activity by forming a complex with plasminogen. A cross-linked staphylokinase/plasminogen complex was produced with disuccinimidyl suberate, and its enzymatic characteristics were compared with those of a ...
Fukao, Hideharu +7 more
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TGF‐β signaling regulates extracellular vesicle (EV) release in cancer cells by modulating the expression and activity of genes associated with EV biogenesis. The TGF‐β‐induced upregulation of RAB4A expression facilitates fast endosomal recycling, a process that limits the fusion of multivesicular bodies with the plasma membrane and EV secretion. Hence,
Dorival Mendes Rodrigues‐Junior +5 more
wiley +1 more source
Proteolytic remodelling of the extracellular matrix by pericytes
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard +4 more
wiley +1 more source
ABSTRACT Introduction The plasminogen activating (PA) system has a multitude of functions such as wound healing, proteolytic activity, collagen degradation and cell growth, and the role of the urokinase plasminogen activator/urokinase plasminogen activator receptor (uPA/uPAR) system has been studied in many disease states.
Ahmed Khudhur +6 more
wiley +1 more source
Sesamol is a component in the nutritional makeup of sesame that was identified as an antioxidant. In recent years, the importance of the plasminogen activator (PA) and its adjustment factor, plasminogen activator inhibitor-1 (PAI-1) , in the prevention ...
CHEN, PEY-RONG;CHANG, HANG;LEE, CHUN-CHUNG +1 more
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ABSTRACT Introduction Investigator‐led research and quality improvement initiatives have led to important improvements in the diagnostic assessment of platelet function disorders (PFD). Methods Personal reflections were used to summarize our contributions to knowledge on PFD diagnostic assessment, pathogenesis, and bleeding risks.
Catherine P. M. Hayward
wiley +1 more source
Plasminogen polymorphism in dairy cattle
A genetic approach to lowering protease (plasmin) levels in milk, requires the presence of polymorphism of bovine plasminogen. This study was conducted to determine to what extent genetic polymorphism exists in dairy cattle.
Wang, Wei
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Calcium oxalate monohydrate (COM) crystals cause changes in the secretion of 29 proteins from neutrophil‐like cells, including those involved in neutrophil immune activation and intracellular metabolic adaptation. The neutrophil secreted proteins (secretome) also inhibit calcium oxalate crystallisation and crystal growth, but promote crystal ...
Chanettee Lertprapai +2 more
wiley +1 more source
Endothelial cells, glial and neuronal cells, representing the principal sources of plasminogen activator (tPA and uPA), are in close interaction in the neurovascular unit. Formation of plasmin at the surface of endothelial cells and neurons has important
Mezzapesa A +6 more
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