Genetic Susceptibility to Periodontitis
Journal of Periodontal Research, EarlyView.Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
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Toll Like Receptor 4: A Potential Link Between Obesity and Metabolic Diseases
Obesity Reviews, EarlyView.ABSTRACT Epidemiological evidence shows that obesity increases the risk of developing metabolic diseases. Nevertheless, the mechanisms behind this connection remain underappreciated. The substantial impact of these disorders on global health has led to extensive research efforts aimed at identifying the pathophysiological links between them.
Ghadeer Alhamar +4 more
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Correction: Exposure of HL-60 human leukaemic cells to 4-hydroxynonenal promotes the formation of adduct(s) with α-enolase devoid of plasminogen binding activity. [PDF]
Biochem JBarrera G +14 more
europepmc +1 more source
Obesity Reviews, EarlyView.Obesity is widely recognized as a pro‐thrombotic condition, yet the specific biomarker profile reflecting coagulation activation remains incompletely defined. Obesity is associated with increased coagulation activation, particularly in children, suggesting an early pro‐thrombotic shift.
Julia Buchold +9 more
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Functional Aspects of Fibrin Structure Alterations by Tranexamic Acid in the Inhibition of Fibrinolysis. [PDF]
BiomoleculesBalog Virag K +9 more
europepmc +1 more source
Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction
Obesity Reviews, EarlyView.Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey +7 more
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Author Correction: COX-2/PGE₂ signaling drives Toxocara canis-induced lung pathology by enhancing plasminogen activator activity and collagen VI degradation. [PDF]
Sci RepLai SC +5 more
europepmc +1 more source
Plasminogen Activator in Epidermal Homeostasis.
, 1982 Increased plasminogen activator activity has been correlated with cell migration and tissue remodelling. The epidermis is a dynamic stratified tissue requiring both cell migration and tissue remodelling to maintain homeostasis. This correlation suggested
Brown, Judith Marion
core
The relationship of soluble urokinase plasminogen activator receptor levels with preterm premature rupture of membranes and predictive value in neonatal intensive care unit admission. [PDF]
Rev Assoc Med Bras (1992)Koc BL +7 more
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Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases
Periodontology 2000, EarlyView.Abstract Understanding the impact of oral health on rheumatoid arthritis (RA) will inform how best to manage patients with both periodontitis and RA. This review seeks to provide an update on interventional and mechanistic investigations, including a brief summary of European Research programs investigating the link between periodontitis and RA. Recent
Isabel Lopez‐Oliva +2 more
wiley +1 more source