Results 181 to 190 of about 136,149 (288)

Adaption of the plasmin generation assay to enhance sensitivity to plasminogen activator inhibitor-1 and establishment of sex-specific reference values in human plasma. [PDF]

Res Pract Thromb Haemost
De Simone I, Pocknell K, Tufaha S, Konings J, Roest M, Wolberg AS, Whyte CS, Mutch NJ, de Laat B, Huskens D.   +9 more
europepmc   +1 more source

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani, Haibo Ni, Jeffrey J Saucerman, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +5 more
wiley   +1 more source

Photobiomodulation restores blood–brain barrier integrity after hypoxia via endothelial von Willebrand factor modulation in a humanised tricellular transwell model

The Journal of Physiology, EarlyView.
Abstract figure legend Photobiomodulation restores blood–brain barrier (BBB) integrity following hypoxic stress. A multicellular human BBB model comprising brain microvascular endothelial cells, astrocytes and pericytes was established in a transwell system and subjected to acute hypoxia.
Mirriam Domocos, Denis E. Bragin, Nagesh C. Shanbhag, Luise Schlotterose, Mootaz M. Salman   +4 more
wiley   +1 more source

Ligneous conjunctivitis presenting after strabismus surgery in the eighth decade of life. [PDF]

Am J Ophthalmol Case Rep
Godfrey AA, Pekmezci M, Seitzman GD, de Alba Campomanes AG.   +3 more
europepmc   +1 more source

Complement inhibition by a unique cluster of immunomodulatory outer surface proteins of Borrelia recurrentis. [PDF]

Nat Commun
Röttgerding F, Reyer F, Gerlach E, Amborn M, Duschek N, Schultze TG, Fingerle V, Roome CM, Stumpf M, Becker K, Rahlfs S, Przyborski JM, Kraiczy P, Fritz-Wolf K.   +13 more
europepmc   +1 more source

Pulsed Electric Field Processing Enhances the Endothelial Bioefficacy of Red Beet (Beta vulgaris L.) Extracts by Restoring Endothelial Nitric Oxide Synthase–Nitric Oxide Signaling in High‐Fat Diet Rats

eFood, Volume 7, Issue 4, August 2026.
Pulsed electric field (PEF) processing qualitatively reshapes the phytochemical profile of red beet extracts, resulting in enhanced endothelial bioefficacy. Compared with conventional extraction, PEF‐treated extracts more effectively restore nitric oxide signaling, suppress endothelial inflammation, and normalize vascular structure in high‐fat diet ...
Eunju Jang, Tae‐Baek Lee, Lisa Tonini, Soobin Choi, YoonA Jeon, Taehyun Kim, Taeyoung Kang, Hyuk‐Joon Choi, Changhwan Ahn   +8 more
wiley   +1 more source

FAST: a 5-minute assay for measuring fibrinolytic activation. [PDF]

Blood Adv
Law RHP, Xie N.
europepmc   +1 more source

Urokinase Plasminogen Activator Receptor‐Associated Protein (uPARAP) as a Potential Next Generation Molecular Target for Treatment of Gastrointestinal Stromal Tumors (GIST)

International Journal of Cancer, Volume 159, Issue 3, Page 797-808, 1 August 2026.
A key component of the collagen internalization and lysosomal degradation cellular machinery, uPARAP may contribute to cancer progression. Here, the authors explored the expression of uPARAP in gastrointestinal stromal tumors using well‐annotated clinical patient samples and specimens from cell line‐ and patient‐derived xenografts.
Chao‐Chi Wang, Flavia Paternostro, Agnieszka Wozniak, Lore De Cock, Luna De Sutter, Kimberly Verbeeck, Ulla Vanleeuw, Daniël Gorgels, Che‐Jui Lee, Raf Sciot, Patrick Schöffski   +10 more
wiley   +1 more source

Role of Tranexamic Acid in Orthopedic Trauma: Current Evidence, Clinical Applications, and Ongoing Controversies. [PDF]

J Orthop Case Rep
Shah ZA, Parveen S, Sajjad A, Ashber I, Rathod R, Nawaz A.   +5 more
europepmc   +1 more source

Bioresorbable Scaffolds for Coronary Arteries: Where Do We Stand Today?

VIEW Medicine, Volume 1, Issue 1, August 2026.
Bioresorbable coronary scaffolds are moving from thick strut pitfalls to thinner, stronger, healing‐oriented designs. Integrating advances in materials, guided implantation with preparation, size, and postdilation steps, and resorption aligned to healing, we synthesize clinical evidence and chart a roadmap toward intelligent, transient platforms ...
Junya Matsuda, Tatsuya Watanabe, Satoshi Yuhara, John M. Kelly, Hirotsugu Kurobe, Toshiharu Shinoka   +5 more
wiley   +1 more source