Results 181 to 190 of about 213,256 (305)

Endothelial thrombomodulin—Its role in trauma‐induced coagulopathy

Transfusion, EarlyView.
Abstract Background Trauma‐induced coagulopathy (TIC) describes a complex set of coagulation changes affecting severely injured patients. The thrombomodulin‐protein C axis is central to the evolution of TIC. Soluble thrombomodulin (sTM) levels are elevated after injury and predict poor clinical outcomes.
Jeries Abu‐Hanna, Gael B. Morrow, Gang Xu, Lewis Timms, Naveed Akbar, Michael Laffan, Robin P. Choudhury, Nicola Curry   +7 more
wiley   +1 more source

Dysregulation of Endothelial cell markers in polycystic ovary syndrome. [PDF]

Sci Rep
Borde P, Niinuma SA, Habib H, Takemoto AS, Nandakumar M, Sathyapalan T, Butler AE, Atkin SL.   +7 more
europepmc   +1 more source

Estrogen as a therapeutic agent: Targeting endotheliopathy and coagulopathy in trauma

Transfusion, EarlyView.
Abstract Background Traumatic injury remains a leading cause of death, often due to uncontrolled hemorrhage and trauma‐induced coagulopathy (TIC). TIC is critically triggered by the endotheliopathy of trauma, involving endothelial cell injury and glycocalyx degradation. Despite conventional advances, the stable casualty rate underscores the urgent need
Niruktha Raghavan, Mira Patel, Bryan A. Cotton, Julia Coleman, Donald Jenkins   +4 more
wiley   +1 more source

Influence of Hemostatic Disorder on Type II Endoleak Development After Endovascular Abdominal Aortic Aneurysm Repair. [PDF]

Int J Mol Sci
Rynio P, Kłysz M, Samad R, Bieniek M, Lisman D, Rybicka A, Skórka P, Lempek P, Cnotliwy M, Kazimierczak A, Gutowski P, Jastrzębska M, Siennicka A.   +12 more
europepmc   +1 more source

An assessment of green plasma: The in vitro hemostatic superiority of a currently discarded blood product

Transfusion, EarlyView.
Abstract Introduction Recent studies have linked trauma patient outcomes to the plasma donor's sex, with premenopausal females associated with improved survival and lower organ failure. Currently, green‐colored plasma (due to oral contraceptive use) is removed from the donor pool. We set out to evaluate the hemostatic potential of green plasma.
Samantha C. Redden, David J. Sun, Yao‐Wei W. Wang, Elizabeth Hartwell, Jessica C. Cardenas, Scott D. Olson, Bryan A. Cotton   +6 more
wiley   +1 more source

The impact of rapid infusers on the hemostatic potential of cryoprecipitate products

Transfusion, EarlyView.
Abstract Background In cases of massive transfusion, intravenous access can be limited. Additionally, delivering different products through separate lines and infusion methods adds unnecessary steps. RBC, plasma, and whole blood (WB) are delivered via rapid infusers; cryoprecipitate (CRYO) is infused through separate access and is not approved with ...
Connor D. Purvis, Samantha Redden, Andrew Jacobson, Yao‐Wei Wang, Julie Campbell, Jessica Cardenas, Jan‐Michael Van Gent, Bryan A. Cotton   +7 more
wiley   +1 more source

The Double-Edged Sword Effect of the Fibrinolytic System in Alzheimer's Disease. [PDF]

Cell Mol Neurobiol
Tang M, Liang M, Zhang X, Hong C, Ye L.
europepmc   +1 more source

Clinical features and prognosis of patients with malignant tumors complicated by cerebral infarction. [PDF]

Am J Cancer Res
Li H, Wu X, Yan X, Guo J, Gao Z.
europepmc   +1 more source

Integrative Phosphoproteomic Profiling Reveals Stage‐Specific Signalling and Metabolism in Equine Melanocytic Neoplasm

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Equine melanocytic neoplasms (EMN) are aggressive tumours characterised by high metastatic potential and limited therapeutic options available. However, the molecular mechanisms underlying their progression remain poorly understood. This study therefore presents the integrative phosphoproteomic analysis of EMN tissue, with the aim of ...
Paitoon Srimontri, Amornthep Kingkaw, Nawarus Prapaiwan, Rangsima Sujittosakul, Nichapat Iamkaewprasert, Jiraschaya Piputwat, Puetta Isama‐al, Thanutchanok Munkongdee, Thanapon Chotikaprakal, Petchpailin Yanyongsirikarn, Narumon Phaonakrop, Sittiruk Roytrakul, Wanwipa Vongsangnak, Parichart Tesena   +13 more
wiley   +1 more source

JAK inhibitors in livedoid vasculopathy associated with thrombophilia and refractory to anticoagulation: report and literature review. [PDF]

An Bras Dermatol
Criado GJ, Criado PR, Lorenzini D, Miot HA.   +3 more
europepmc   +1 more source