Results 191 to 200 of about 151,729 (305)

Enolase-1 and Inflammation. [PDF]

Biomolecules
Fernandez R, Jacob A, Aziz M, Wang P.
europepmc   +1 more source

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani, Haibo Ni, Jeffrey J Saucerman, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +5 more
wiley   +1 more source

Antifibrinolytic strategies improve liver regeneration in mice and reduce posthepatectomy liver failure in patients.

Blood
Li Z, Wei Z, Groeneveld DJ, Strilchuk AW, Flick MJ, Dong Y, Podrascanin V, Truty MJ, Kendrick ML, Cleary SP, Warner SG, Smoot RL, Assinger A, Kastrup CJ, Karanicolas P, Luyendyk JP, Starlinger PP.   +16 more
europepmc   +1 more source

Tetranectin: Molecular Mechanisms, Biological Functions and Clinical Implications. [PDF]

Int J Mol Sci
Ahmed S, Iram S, Akash A, Kim K, Kim J.
europepmc   +1 more source

Warburg redefined: Metabolites, mitochondria and macrophages in immune regulation

The Journal of Physiology, EarlyView.
Abstract figure legend Following pro‐inflammatory stimulation, macrophages undergo Warburg‐like metabolic rewiring that extends more than increased glycolysis. The non‐canonical functions of glycolytic enzymes and lactate accumulation control macrophage immune responses through multiple signalling pathways (a).
Yukun Min, Órlaith C. Henry, Luke A. J. O'Neill   +2 more
wiley   +1 more source

Contribution of genetic markers to cerebral venous thrombosis risk among Tunisian patients: A case-control study. [PDF]

eNeurologicalSci
Moalla K, Smaoui E, Sakka S, Megdiche F, Bouattour N, Belhassen I, Smaoui R, Kallel C, Damak M.   +8 more
europepmc   +1 more source

Rather a versatile multi-tool than a sword: an integral role of the plasminogen system in health and disease. [PDF]

Front Immunol
Skrabana R, Castven M, Tomková M, Sedlák E, Babulic P, Jakubcova M, Moskalets T, Leksa V.   +7 more
europepmc   +1 more source

Safety and Effectiveness of a High‐Dose, Tailored Tissue Plasminogen Activator Therapy Protocol: A Joint Pediatric Hematology and Cardiac ICU Quality Improvement Initiative Analysis

Pediatric Blood &Cancer, Volume 73, Issue 11, November 2026.
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak, Oded Gilad, Yael Feinstein, Sigal Nakav, Ofer Schiller, Joanne Yacobovich   +5 more
wiley   +1 more source

Tenecteplase for Acute Ischemic Stroke: From Molecular Bioengineering to Phase III Pivotal Trials. [PDF]

J Stroke
Jung JW, Lee JS.
europepmc   +1 more source