Results 191 to 200 of about 136,538 (301)

Thromboinflammation and hemostatic activation drive early mortality risk in pulmonary embolism. [PDF]

Res Pract Thromb Haemost
Siddiqui F, Tafur A, Darki A, Kantarcioglu B, Hoppensteadt D, Walenga J, Monreal M, Fareed J.   +7 more
europepmc   +1 more source

Just one thing to reduce bleeding: Put tranexamic acid on the safe surgical checklist at your hospital

Transfusion Medicine, EarlyView.
Abstract Objectives To highlight tranexamic acid (TXA) as ‘just one thing’ that every hospital could implement to reduce surgical bleeding and blood transfusions. Background TXA is a low‐cost antifibrinolytic agent that inhibits the breakdown of fibrin blood clots. Developed in Japan in the 1960s, it has been shown to reduce surgical bleeding.
Ian Roberts, Katharine Ker
wiley   +1 more source

Another step toward phenotypic characterization of hereditary dysfibrinogenemia? [PDF]

Res Pract Thromb Haemost
Casini A.
europepmc   +1 more source

Integrative Phosphoproteomic Profiling Reveals Stage‐Specific Signalling and Metabolism in Equine Melanocytic Neoplasm

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Equine melanocytic neoplasms (EMN) are aggressive tumours characterised by high metastatic potential and limited therapeutic options available. However, the molecular mechanisms underlying their progression remain poorly understood. This study therefore presents the integrative phosphoproteomic analysis of EMN tissue, with the aim of ...
Paitoon Srimontri, Amornthep Kingkaw, Nawarus Prapaiwan, Rangsima Sujittosakul, Nichapat Iamkaewprasert, Jiraschaya Piputwat, Puetta Isama‐al, Thanutchanok Munkongdee, Thanapon Chotikaprakal, Petchpailin Yanyongsirikarn, Narumon Phaonakrop, Sittiruk Roytrakul, Wanwipa Vongsangnak, Parichart Tesena   +13 more
wiley   +1 more source

Vision outcomes in dogs with primary glaucoma surgically treated with lensectomy and endolaser cyclophotocoagulation after an Ahmed valve gonioimplantation failure

Veterinary Ophthalmology, Volume 28, Issue 2, Page 207-217, March 2025.
Abstract Objective The aim of this study was to retrospectively evaluate vision outcomes of dogs with primary angle closure glaucoma (PACG) that underwent Ahmed valve gonioimplantation (AVG) followed by lensectomy and endolaser cyclophotocoagulation (ECP) with or without bleb resection after AVG failure.
Bactelius Turicea, Christian L. Munevar, Sydney G. Edwards, Lana L. Linton   +3 more
wiley   +1 more source

uPAR/suPAR Signaling and Organ Crosstalk in Cardiovascular-Kidney-Metabolic Syndrome. [PDF]

Circ Res
Hayek SS, Dryer SE.
europepmc   +1 more source

Senolytics and exercise: Dual modalities for rejuvenating muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican, Ce Qi, Uchenna Okpechi, Maya Strand Ford, Georgina M. Ellison‐Hughes   +4 more
wiley   +1 more source

Lymphatic Malformations With Activating KRAS Mutations Impair Lymphatic Valve Development Through Matrix Metalloproteinases. [PDF]

Arterioscler Thromb Vasc Biol
Mastrogiacomo DM, Price A, Fu Y, Banerjee R, Knauer LA, Li K, Yang Y, Davis GE, Dellinger MT, Scallan JP.   +9 more
europepmc   +1 more source

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani, Haibo Ni, Jeffrey J Saucerman, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +5 more
wiley   +1 more source

A Narrative Review on Abnormalities in the Hemostatic System in Diabetes Mellitus: Pathophysiology, Clinical Implications, and Therapeutics. [PDF]

Life (Basel)
Rafaqat S, Hamid H, Bashir F, Abaid H, Klisic A, Rafaqat S, Mercantepe F.   +6 more
europepmc   +1 more source