Results 201 to 210 of about 136,149 (288)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, Volume 20, Issue 6, Page 1556-1590, June 2026.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Association of VTN Genotype with Plasminogen Activator Inhibitor-1 Activity in Late-Onset Alzheimer's Disease. [PDF]

Genes (Basel)
Agirbasli D, Agirbasli M, Cakir ME, Muftuoglu M.   +3 more
europepmc   +1 more source

Toward improved thrombolysis in ischemic stroke: targeting nonfibrin components. [PDF]

Res Pract Thromb Haemost
De Meyer SF.
europepmc   +1 more source

Plasminogen Activator Inhibitor-1 as a Therapeutic Target for Healthy Longevity, Immunosenescence, and Age-Related Disease: Translational Development of the Small-Molecule Inhibitor TM5614. [PDF]

Cells
Abdelhakim M, Miyata T.
europepmc   +1 more source

Tissue Plasminogen Activator [PDF]

New England Journal of Medicine, 1989
openaire   +2 more sources

COMPARABLE RESULTS OF SUBRETINAL INJECTION AND INTRAVITREAL INJECTION OF TISSUE PLASMINOGEN ACTIVATOR IN THE TREATMENT OF SUBMACULAR HEMORRHAGE: A Meta-Analysis of Efficacy. [PDF]

Retina
Zhang L, Zhang Y, Si W, Wang X, Jiang S, Qin X.   +5 more
europepmc   +1 more source

Cathepsin G is associated with cerebral vascular injury in myeloid leukemia: a pathologic insight into intracranial hemorrhage. [PDF]

Res Pract Thromb Haemost
Gi T, Kai K, Shide K, Nakamura E, Oguri N, Aman M, Maekawa K, Moriguchi-Goto S, Nakai M, Shimoda K, Hisada Y, Yamashita A.   +11 more
europepmc   +1 more source

Extended Intrapleural Tissue Plasminogen Activator (tPA)-Dornase Alfa (DNase) Therapy Beyond the Standard Multicenter Intrapleural Sepsis Trial 2 (MIST-2) Regimen in a High-Risk Patient With Complex Empyema: A Case Report. [PDF]

Cureus
Furlan Silva Fabri R, De Melo Rodrigues RM, Zhou DL, Kishore E, Mohankumar P, Opina M, Schuller D, Kicker P.   +7 more
europepmc   +1 more source

Leptospira glyceraldehyde-3-phosphate dehydrogenase (LiGAPDH): a cell-surface plasminogen binding protein. [PDF]

FEMS Microbiol Lett
de Souza MCL, Nepomuceno R, Santos CM, Abe CM, Barbosa AS.   +4 more
europepmc   +1 more source