Results 201 to 210 of about 151,729 (305)

Mast cells enhance venous thrombus stability and lung fibrin deposition in murine sepsis. [PDF]

open access: yesBlood Adv
Rayes J   +5 more
europepmc   +1 more source

Proteomic signatures of equine dental tooth tissues in ageing and disease

open access: yesEquine Veterinary Journal, Volume 58, Issue 6, Page 1552-1569, November 2026.
Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen   +8 more
wiley   +1 more source

Reference Intervals for ROTEM-tPA: Whole-Blood Fibrinolysis Assessment in Healthy Adults. [PDF]

open access: yesTH Open
Malte AL   +6 more
europepmc   +1 more source

Revisiting Inherited Metabolic Diseases (IMDs) Through the Lens of Selective Autophagy

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Selective autophagy is increasingly recognized as a fundamental quality‐control mechanism that complements bulk autophagy by enabling the targeted degradation of specific intracellular cargos, including mitochondria, endoplasmic reticulum (ER), lipid droplets, glycogen, peroxisomes, ferritin, ribosomes, and protein aggregates.
Marianna Maddaluno   +3 more
wiley   +1 more source

Leptin Neutralization Attenuates Inflammaging in Endothelial and Immune Cell Models

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Multiple mechanisms including senescent cell accumulation, metabolic and endotoxin‐driven stimulation of immune and endothelial cells contribute to inflammaging, the chronic low‐grade inflammatory status underlying age‐related diseases. Blocking leptin signaling in experimental models of inflammaging blunts inflammation in a model‐specific manner while
Valeria Pellegrini   +20 more
wiley   +1 more source

A covalent peptide engager approach to equip immunotherapeutic monoclonal and pan IgG serum antibodies with new tumour‐targeting function

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 22, Page 6685-6703, November 2026.
Abstract Background and Purpose Site‐specific antibody modification is a useful chemical strategy to elaborate antibody therapeutic function. Conventional lysine‐ or cysteine‐based conjugation methods generate heterogeneous products, while protein engineering approaches are resource‐intensive.
Karolina Krygier   +2 more
wiley   +1 more source

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