Results 301 to 310 of about 315,782 (393)

Thermodynamics and selection of the plasminogen activator inhibitor-1 latency transition. [PDF]

J Biol Chem
Haynes LM, Holding ML, Woodard J, Siemieniak D, Ginsburg D.   +4 more
europepmc   +1 more source

Efficacy and safety of glucagon‐like peptide 1 receptor agonists across all health outcomes in type 2 diabetes: An umbrella review and evidence map of randomised controlled trials

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1136-1149, February 2026.
Abstract Aim Glucagon‐like peptide 1 receptor agonists (GLP‐1RAs) have been established as effective treatments for type 2 diabetes, offering benefits beyond glycaemic control; however, their associations across multiple health outcomes remain insufficiently assessed.
Dongjin Yeo, Yeona Jo, Jinyoung Jeong, Yi Deun Jeong, Ho Geol Woo, Yejun Son, Sunyoung Kim, Sang Youl Rhee, Dong Keon Yon   +8 more
wiley   +1 more source

Plasminogen activation and plasmin activity are not necessary to prevent venous thrombosis/thromboembolism. [PDF]

Blood
Sang Y, Menegatti M, Brody JA, Wiggins KL, Cooley BC, Kapfer KN, Kangro K, de Laat B, Peyvandi F, Flick MJ, Smith NL, Shapiro AD, Wolberg AS.   +12 more
europepmc   +1 more source

Tranexamic Acid for Hyperpigmentation Disorders: A Literature Review on Efficacy and Safety in Melasma and PIH

Journal of Cosmetic Dermatology, Volume 25, Issue 2, February 2026.
ABSTRACT Background Hyperpigmentation disorders, including melasma and post‐inflammatory hyperpigmentation (PIH), are common dermatologic conditions associated with significant cosmetic and psychological burden. Tranexamic acid (TXA), an antifibrinolytic agent, has gained increasing attention due to its anti‐inflammatory and antimelanogenic properties.
Ahmed AlJabr, Aseel Muhana I. AlAnazi, Rakan Abdulkarim A. AlEtebi   +2 more
wiley   +1 more source

Placental Dysfunction Is Associated with Dysregulated Fibrinolytic System Activation. [PDF]

Int J Mol Sci
Yatsenko T, Us I, Korolova D, Zhuk S, Dziuba H, Nalbat A, Kharchenko S, Vari SG, Chernyshenko V.   +8 more
europepmc   +1 more source

Environmental modulators of vascular physiology and inflammation

Experimental Physiology, Volume 111, Issue 2, Page 321-334, 1 February 2026.
Abstract Environmental factors play a crucial role in modulating vascular inflammation, contributing significantly to the development of atherosclerosis and cardiovascular disease. This review synthesizes current evidence on how various environmental exposures influence vascular function and inflammation, with a focus on pollutants such as particulate ...
Anusha N. Seneviratne, Anne Majumdar, Kalpana Surendranath, Mark R. Miller   +3 more
wiley   +1 more source

Myocardial Infarction in a Patient With Homozygous Plasminogen Activator Inhibitor-1 (PAI-1) 4G/4G Mutation: A Case Report. [PDF]

Cureus
Manasrah A, Khan F, Yarkoni A, Kashou H, Rehman A.   +4 more
europepmc   +1 more source

Isoquercetin and Zafirlukast Cooperatively Suppress Tumor Growth and Thromboinflammatory Signaling in a Xenograft Model of Ovarian Cancer

The FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Treatment using either the thiol isomerase inhibitor isoquercetin or zafirlukast lowers tissue factor levels, decreases VEGF, inhibits PD‐L1, and TMEM176B in a xenograft model of ovarian cancer. A combination of the two agents, at threefold lower concentrations than either drug, significantly enhanced the inhibition further, suggesting a dual action of
Justine A. Keovilay, Jason W. Hoskins, Jean‐Pierre Kinet, Thomas C. Lines, Daniel R. Kennedy   +4 more
wiley   +1 more source

Enolase AmEno15, a Promising Candidate for Understanding the Infectious Process of <i>Anaplasma marginale</i>. [PDF]

Int J Mol Sci
López-López MDS, Aguilar-Díaz H, Burgos-Solorio A, Quiroz-Castañeda RE.   +3 more
europepmc   +1 more source

SARS-CoV-2 Spike Protein Amyloid Fibrils Impair Fibrin Formation and Fibrinolysis. [PDF]

Biochemistry
Westman H, Hammarström P, Nyström S.
europepmc   +1 more source