Results 11 to 20 of about 200,214 (356)
Activation of Plasminogen by Staphylokinase [PDF]
Nature, 1960 SOME animal plasminogens, which are unaffected by streptokinase alone, are activated by streptokinase and human globulin. Mullertz1 has postulated the existence of a proactivator in human serum. Staphylokinase, without human globulin, activates a wider range of animal plasminogens2 and may, therefore, not require proactivator.
Flora M. Davidson
openalex +4 more sources
Phosphorylation of human plasminogen activators and plasminogen [PDF]
FEBS Letters, 1995 Plasminogen (PG), urokinase‐type plasminogen activator (u‐PA) and tissue‐type PA (t‐PA) are the main molecules involved in fibrinolysis and in many other physiological and pathological processes. In the present study we report that human t‐PA, purified from human melanoma cells, and PG, purified from human plasma, both contain P‐Tyr residues, as ...
BARLATI, Sergio +4 more
openaire +4 more sources
Plasminogen activator inhibitors [PDF]
Blood, 1987 Chemicals/CAS: fibrin, 9001-31-4; plasminogen activator inhibitor, 105844-41-5; plasminogen activator, 9039-53-6; Carrier Proteins; Glycoproteins; Plasminogen Activators, EC 3.4.21.-; Plasminogen Inactivators; Protease Inhibitors; protease ...
Sprengers, E.D., Kluft, C.
openaire +5 more sources
Fibrinolysis regulation by platelets retaining plasminogen and tissue-type plasminogen activator on their surface [PDF]
The Ukrainian Biochemical Journal, 2019 Platelets play a key role in hemostasis as cofactors of thrombin generation, fibrin polymerization centers, and initiators of clot retraction, while their ability to modulate clot dissolution remains less understood.
T. Grinenko +4 more
doaj +1 more source
Plasminogen activators and plasminogen activator inhibitors in endometriosis
Frontiers in Bioscience, 2005 Endometriosis is one of the most frequent benign gynecological diseases that affect women. Little is known about the pathogenesis and etiology of endometriosis, despite the numerous studies performed in this field. Although endometriosis is a benign disease, the endometrial tissue, after attachment to the peritoneum, has the ability to grow and invade ...
Luis A. Ramón +6 more
openaire +4 more sources
Plasminogen Activator – Multifunctional Protein of Plague Pathogen
Проблемы особо опасных инфекций, 2016 Yersinia pestis plasminogen activator, a surface protease (Pla) is encoded by species-specific plasmid pPla. This enzyme belongs to outer membrane protein family and has a ß-barrel structure.
L. M. Kukleva, A. V. Boiko
doaj +1 more source
Frontiers in Pharmacology, 2021 Adenosine A2A receptor mediates the promotion of wound healing and revascularization of injured tissue, in healthy and animals with impaired wound healing, through a mechanism depending upon tissue plasminogen activator (tPA), a component of the ...
María D. Valls +14 more
doaj +1 more source
Leukocyte- and endothelial-derived microparticles: a circulating source for fibrinolysis
Haematologica, 2012 Background We recently assigned a new fibrinolytic function to cell-derived microparticles in vitro. In this study we explored the relevance of this novel property of microparticles to the in vivo situation.Design and Methods Circulating microparticles ...
Romaric Lacroix +14 more
doaj +1 more source
Pericellular activation of hepatocyte growth factor by the transmembrane serine proteases matriptase and hepsin, but not by the membrane-associated protease uPA [PDF]
, 2009 HGF (hepatocyte growth factor) is a pleiotropic cytokine homologous to the serine protease zymogen plasminogen that requires canonical proteolytic cleavage to gain functional activity.
Andrew M. Schumacher +47 more
core +3 more sources
Yersinia pestis Plasminogen Activator
Biomolecules, 2020 The Gram-negative bacterium Yersinia pestis causes plague, a fatal flea-borne anthropozoonosis, which can progress to aerosol-transmitted pneumonia. Y.
Florent Sebbane +2 more
doaj +1 more source