Results 11 to 20 of about 3,479,441 (357)
Clinical and Applied Thrombosis/Hemostasis, 2023 Background Vitamin D deficiency has recently been suggested as an independent risk factor for thrombosis. Notably, vitamin D deficiency is common in pregnant populations, whom already have an increased thrombotic risk.
Matilde Kanstrup Andersen BA +6 more
doaj +1 more source
Phosphorylation of human plasminogen activators and plasminogen [PDF]
FEBS Letters, 1995 Plasminogen (PG), urokinase‐type plasminogen activator (u‐PA) and tissue‐type PA (t‐PA) are the main molecules involved in fibrinolysis and in many other physiological and pathological processes. In the present study we report that human t‐PA, purified from human melanoma cells, and PG, purified from human plasma, both contain P‐Tyr residues, as ...
BARLATI, Sergio +4 more
openaire +3 more sources
A novel serine protease secreted by medicinal maggots enhances plasminogen activator-induced fibrinolysis. [PDF]
PLoS ONE, 2014 Maggots of the blowfly Lucilia sericata are used for the treatment of chronic wounds. As haemostatic processes play an important role in wound healing, this study focused on the effects of maggot secretions on coagulation and fibrinolysis.
Mariena J A van der Plas +9 more
doaj +1 more source
Plasminogen activators and plasminogen activator inhibitors in endometriosis
Frontiers in Bioscience, 2005 Endometriosis is one of the most frequent benign gynecological diseases that affect women. Little is known about the pathogenesis and etiology of endometriosis, despite the numerous studies performed in this field. Although endometriosis is a benign disease, the endometrial tissue, after attachment to the peritoneum, has the ability to grow and invade ...
Gilabert-Estelles, J +6 more
openaire +4 more sources
PLoS ONE, 2017 Due to controversial evidence in the literature pertaining to the activity of plasminogen activator inhibitor-1 in platelets, we examined the effects of residual platelets present in plasma (a potential pre-analytical variable) on various plasminogen ...
Marlien Pieters +3 more
doaj +1 more source
Peripheral embolization following thrombolytic therapy for acute ischemic stroke—a case report
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2020 Background Intravenous recombinant tissue plasminogen activator is the only golden approved medical therapy for acute ischemic stroke, guidelines for its injection relay on reducing or preventing associated hemorrhage as a side effect, yet hemorrhage is ...
Tamer Roushdy +5 more
doaj +1 more source
Fibrinolysis regulation by platelets retaining plasminogen and tissue-type plasminogen activator on their surface [PDF]
The Ukrainian Biochemical Journal, 2019 Platelets play a key role in hemostasis as cofactors of thrombin generation, fibrin polymerization centers, and initiators of clot retraction, while their ability to modulate clot dissolution remains less understood.
T. Grinenko +4 more
doaj +1 more source
Plasminogen Activator – Multifunctional Protein of Plague Pathogen
Проблемы особо опасных инфекций, 2016 Yersinia pestis plasminogen activator, a surface protease (Pla) is encoded by species-specific plasmid pPla. This enzyme belongs to outer membrane protein family and has a ß-barrel structure.
L. M. Kukleva, A. V. Boiko
doaj +1 more source
Leukocyte- and endothelial-derived microparticles: a circulating source for fibrinolysis
Haematologica, 2012 Background We recently assigned a new fibrinolytic function to cell-derived microparticles in vitro. In this study we explored the relevance of this novel property of microparticles to the in vivo situation.Design and Methods Circulating microparticles ...
Romaric Lacroix +14 more
doaj +1 more source
Frontiers in Pharmacology, 2021 Adenosine A2A receptor mediates the promotion of wound healing and revascularization of injured tissue, in healthy and animals with impaired wound healing, through a mechanism depending upon tissue plasminogen activator (tPA), a component of the ...
María D. Valls +14 more
doaj +1 more source