Results 31 to 40 of about 3,602,430 (295)
Role of Plasminogen Activator Inhibitor Type 1 in Pathologies of Female Reproductive Diseases
International Journal of Molecular Sciences, 2017 Normal pregnancy is a state of hypercoagulability with diminishing fibrinolytic activity, which is mainly caused by an increase of plasminogen activator inhibitor type 1 (PAI-1).
Y. Ye +7 more
semanticscholar +1 more source
Plasminogen–receptor KT: plasminogen activation and beyond [PDF]
Journal of Thrombosis and Haemostasis, 2017 The cell surface orchestrates plasminogen activation through the concomitant binding of plasminogen and plasminogen activators to specific receptors. In this issue, Miles and colleagues describe their detailed phenotypic characterization of mice deficient in Plg-RKT, a key plasminogen receptor expressed in numerous tissues, but highly expressed by ...
M J, Flick, T H, Bugge
openaire +2 more sources
Sex Differences in rt-PA Utilization at Hospitals Treating Stroke: The National Inpatient Sample. [PDF]
, 2017 BACKGROUND AND PURPOSE: Sex and race disparities in recombinant tissue plasminogen activator (rt-PA) use have been reported. We sought to explore sex and race differences in the utilization of rt-PA at primary stroke centers (PSCs) compared to non-PSCs ...
Albright, Karen C +7 more
core +2 more sources
Successful Treatment of Arterial Thrombus in an Extremely Low-Birth-Weight Preterm Neonate
Pediatrics and Neonatology, 2013 Arterial thromboembolism in the pediatric population frequently occurs secondary to arterial catheterization. Catheterization-related complications are more common in smaller and sicker infants, due to high prothrombotic activity, low levels of natural ...
Petek G. Kayıran +2 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2023 Severe acute respiratory syndrome coronavirus-2 causes hyperinflammation and activation of coagulation cascade and, as a result, aggravates endothelial cell dysfunction. N-acetylcysteine and Sulodexide have been found to mitigate endothelial damage.
Justyna Rajewska-Tabor +5 more
doaj +1 more source
SAGE Open Medical Case Reports, 2019 Introduction: Few published reports highlight intravenous tissue plasminogen activator use during the first trimester of pregnancy and provide outcomes for mother and fetus.
Gary D Peksa, Jamie Ostrem, Teresa Davis
doaj +1 more source
Protease inhibitors prevent plasminogen-mediated, but not pemphigus vulgaris-induced, acantholysis in human epidermis [PDF]
, 2003 Pemphigus is an autoimmune blistering disease of the skin and mucous membranes. It is caused by autoantibodies directed against desmosomes, which are the principal adhesion structures between epidermal keratinocytes.
Besch, R. +9 more
core +1 more source
Characterization of an Inhibitor of Neuronal Plasminogen Activator Released by Heart Cells [PDF]
, 1987 A basic understanding of growth cone dynamics and developmental events involving growth cones requires an understanding of the function and regulation of molecules associated with and released by growth cones. Rat sympathetic neurons in culture release a
Patterson, Paul H., Pittman, Randall N.
core +1 more source
HGF modulates actin cytoskeleton remodeling and contraction in testicular myoid cells [PDF]
, 2015 The presence of the HGF/Met system in the testicular myoid cells was first discovered by our group. However, the physiological role of this pathway remains poorly understood. We previously reported that HGF increases uPA secretion and TGF-β activation in
Angela, Catizone +6 more
core +1 more source
Neural Regeneration ResearchRecombinant tissue plasminogen activator is commonly used for hematoma evacuation in minimally invasive surgery following intracerebral hemorrhage. However, during minimally invasive surgery, recombinant tissue plasminogen activator may come into contact
Jie Jing +9 more
doaj +1 more source