Therapeutic options for human papillomavirus‐positive tonsil and base of tongue cancer
Abstract The incidences of human papillomavirus‐positive (HPV+) tonsillar and base tongue squamous cell carcinomas (TSCC and BOTSCC) have increased in recent decades. Notably, HPV+ TSCC and BOTSCC have a significantly better prognosis than their HPV‐negative counterparts when treated with current surgical options, radiotherapy, or intensified ...
Mark Zupancic+3 more
wiley +1 more source
Plasminogen activator inhibitor (PAI-1) antigen levels in primary TTP and secondary TTP post-bone marrow transplantation [PDF]
Maya T. Anthony+12 more
openalex +1 more source
ABSTRACT Introduction Several biomarkers in peri‐implant crevicular fluid have been studied to diagnose peri‐implant diseases with inconclusive results. This systematic review and meta‐analysis aimed to comprehensively compare data on the levels of biological components in peri‐implant crevicular fluid collected from healthy and diseased implants to ...
Gerardo La Monaca+5 more
wiley +1 more source
Processing of type 1 plasminogen activator inhibitor (PAI-1) into the regulated secretory pathway.
L. Gombau, Raymond R. Schleef
openalex +1 more source
VLDL activation of plasminogen activator inhibitor-1 (PAI-1) expression: Involvement of the VLDL receptor [PDF]
Ola Nilsson+7 more
openalex +1 more source
Preclinical study examining Porphyromonas gingivalis lipopolysaccharide‐induced global gene expression changes in HGK. Genes associated with the uPA and complement/coagulation (PLAU, PLAUR, Serpin B2) and IL‐1 and cytokine activity (IL‐1b, IL‐1RN, IL‐36G, CXCL14) biological pathways were significantly altered.
Mahyar Ostadkarampour+1 more
wiley +1 more source
Regenerative Potential of PDL‐Derived Small Extracellular Vesicles
Treatment of gingival fibroblasts with PDL extracellular vesicles results in promotion of Wnt signalling pathway and osteogenic differentiation. PDL secretome shows selective wound healing and matrix remodelling which can have implications for future periodontal regenerative strategies.
Anahid A. Birjandi+4 more
wiley +1 more source
The active conformation of plasminogen activator inhibitor 1, a target for drugs to control fibrinolysis and cell adhesion [PDF]
Allan M. Sharp+7 more
openalex +1 more source
Salivary Proteomics for Detecting Novel Biomarkers of Periodontitis: A Systematic Review
Untargeted salivary proteomics identified promising biological molecules consistently over‐ or under‐expressed in periodontitis patients compared to periodontally healthy subjects, but further targeted approaches are required for their validation. ABSTRACT Aim Salivary content is regarded as a powerful diagnostic window for oral and systemic diseases ...
Matteo Corana+7 more
wiley +1 more source
Plasminogen Activator Inhibitor-1 Contains a Cryptic High Affinity Binding Site for the Low Density Lipoprotein Receptor-related Protein [PDF]
Steingrimur Stefansson+5 more
openalex +1 more source