Results 171 to 180 of about 14,970 (304)

Adverse events of tissue plasminogen activators in acute myocardial infarction patients: a real-world and pharmacovigilance database analysis. [PDF]

BMC Cardiovasc Disord
Liu F, Yang G, Xie J, Xie P, Zhou F, Yang F, Ma Y, Xu F.   +7 more
europepmc   +1 more source

Plasminogen activation in melanocytic neoplasia

, 1994
A large body of experimental evidence suggests that plasminogen activators provide tumoral cells with efficient means to degrade extracellular matrix constituents and thereby facilitate their dissemination to distant sites.
Vassalli, Jean-Dominique, Masouyé, Isabelle, Sappino, Pascal, Saurat, Jean-Hilaire, Delbaldo, Catherine Suzanne   +4 more
core  

Plasminogen activators and ischemic stroke: conditions for acute delivery. [PDF]

Semin Thromb Hemost, 2013
del Zoppo GJ.
europepmc   +1 more source

The effect of the environment on plasminogen activators and inhibitors

, 1998
The aims of this project were to develop a reliable assay for the investigation of small changes in mRNA expression of tissue plasminogen activator (tPA) and Plasminogen Activator Inhibitor (PAI-1) in endothelial cell as a response to changes in ...
Alison J. Woods (7690889)
core  

Crystal Structure of the Michaelis Complex between Tissue-type Plasminogen Activator and Plasminogen Activators Inhibitor-1. [PDF]

J Biol Chem, 2015
Gong L, Liu M, Zeng T, Shi X, Yuan C, Andreasen PA, Huang M.   +6 more
europepmc   +1 more source

Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases

Periodontology 2000, EarlyView.
Abstract Understanding the impact of oral health on rheumatoid arthritis (RA) will inform how best to manage patients with both periodontitis and RA. This review seeks to provide an update on interventional and mechanistic investigations, including a brief summary of European Research programs investigating the link between periodontitis and RA. Recent
Isabel Lopez‐Oliva, Jennifer Malcolm, Shauna Culshaw   +2 more
wiley   +1 more source

Etiology, pathogenesis and treatment of peri‐implantitis: A European perspective

Periodontology 2000, EarlyView.
Abstract Peri‐implantitis is a plaque‐associated pathological condition occurring in tissues around dental implants. It is characterized by inflammation in the peri‐implant mucosa and progressive loss of supporting bone. Over the last 30 years, peri‐implantitis has become a major disease burden in dentistry.
Tord Berglundh, Andrea Mombelli, Frank Schwarz, Jan Derks   +3 more
wiley   +1 more source

Distinct encounter complexes of PAI-1 with plasminogen activators and vitronectin revealed by changes in the conformation and dynamics of the reactive center loop. [PDF]

Protein Sci, 2016
Qureshi T, Goswami S, McClintock CS, Ramsey MT, Peterson CB.   +4 more
europepmc   +1 more source

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer, Luigi Nibali, Noha Zoheir, Niki M. Moutsopoulos, Bruno G. Loos   +4 more
wiley   +1 more source

Plasminogen activators in ischemic stroke: introduction. [PDF]

Stroke, 2010
del Zoppo GJ.
europepmc   +1 more source