Results 91 to 100 of about 317,079 (354)

Genomes of all known members of a Plasmodium subgenus reveal paths to virulent human malaria

Nature Microbiology, 2018
Plasmodium falciparum, the most virulent agent of human malaria, shares a recent common ancestor with the gorilla parasite Plasmodium praefalciparum.
T. Otto, A. Gilabert, Thomas Crellen, U. Böhme, C. Arnathau, M. Sanders, Samuel O. Oyola, A. Okouga, L. Boundenga, E. Willaume, B. Ngoubangoye, N. Moukodoum, C. Paupy, P. Durand, Virginie Rougeron, B. Ollomo, F. Renaud, C. Newbold, M. Berriman, F. Prugnolle   +19 more
semanticscholar   +1 more source

Population pharmacokinetics of lumefantrine in pregnant and non‐pregnant women with uncomplicated Plasmodium falciparum malaria in Western Kenya

British Journal of Clinical Pharmacology, EarlyView.
Aim This study intends to assess the pharmacokinetic properties and treatment response of lumefantrine in pregnant and non‐pregnant women with uncomplicated Plasmodium falciparum malaria infection in Western Kenya. Methods Seventy‐five women with uncomplicated P.
Elizabeth Juma, Junjie Ding, Martin Ongas, Nelly Koskei, Kevin Onyango, Florence Oloo, Rashid Aman, Gilbert Kokwaro, Joel Tarning, Bernhards Ogutu   +9 more
wiley   +1 more source

RNA-Seq Analysis Illuminates the Early Stages of Plasmodium Liver Infection [PDF]

, 2020
Maria Toro-Moreno, Kayla Sylvester, Tamanna Srivastava, Dora Posfai, Emily R. Derbyshire   +4 more
openalex   +1 more source

Global Epidemiology of Plasmodium vivax

American Journal of Tropical Medicine and Hygiene, 2016
Plasmodium vivax is the most widespread human malaria, putting 2.5 billion people at risk of infection. Its unique biological and epidemiological characteristics pose challenges to control strategies that have been principally targeted against Plasmodium
R. Howes, K. Battle, K. Mendis, David L. Smith, R. Cibulskis, J. Baird, Simon Iain Hay   +6 more
semanticscholar   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

Effects of the G-quadruplex-binding drugs quarfloxin and CX-5461 on the malaria parasite Plasmodium falciparum

, 2023
Holly M. Craven, Guilherme Nettesheim, Pietro Cicuta, Andrew M. Blagborough, Catherine J. Merrick   +4 more
openalex   +1 more source

Plasmodium malariae and P. ovale genomes provide insights into malaria parasite evolution

Nature, 2017
Elucidation of the evolutionary history and interrelatedness of Plasmodium species that infect humans has been hampered by a lack of genetic information for three human-infective species: P. malariae and two P. ovale species (P. o. curtisi and P.
Gavin G. Rutledge, U. Böhme, M. Sanders, A. Reid, J. Cotton, Oumou Maiga-Ascofare, A. Djimde, T. Apinjoh, L. Amenga-Etego, M. Manske, J. Barnwell, F. Renaud, B. Ollomo, F. Prugnolle, N. Anstey, Sarah Auburn, R. Price, J. McCarthy, D. Kwiatkowski, C. Newbold, M. Berriman, T. Otto   +21 more
semanticscholar   +1 more source

Getting ahead of the crises: Developing an avian malaria disease management plan for Hawaiian forest birds

Conservation Science and Practice, EarlyView.
Avian malaria poses a growing threat to native Hawaiian forest birds as climate change enables its spread into previously disease‐free areas like Hakalau Forest National Wildlife Refuge. This study presents a proactive, tiered disease management plan to help land managers monitor and respond to malaria risk, offering a model for broader conservation ...
Eben H. Paxton, Eldridge Naboa, Nicholas R. Agorastos, Donna L. Ball, Lucas Berio Fortini, Thomas Cady, Richard J. Camp, Patrick J. Hart, Springer Kaye, Steven J. Kendall, Dennis A. LaPointe, Ricardo D. Lopez, Katherine M. McClure, Amanda K. Navine   +13 more
wiley   +1 more source

Immunity against sexual stage Plasmodium falciparum and Plasmodium vivax parasites

Immunological Reviews, 2019
The efficient spread of malaria from infected humans to mosquitoes is a major challenge for malaria elimination initiatives. Gametocytes are the only Plasmodium life stage infectious to mosquitoes.
Roos M. de Jong, Surafel K Tebeje, Lisette Meerstein-Kessel, F. Tadesse, M. M. Jore, W. Stone, T. Bousema   +6 more
semanticscholar   +1 more source

Gonadulin and Insulin‐Like Growth Factor Involved in Rhipicephalus microplus Reproduction

Entomologia Experimentalis et Applicata, EarlyView.
Insulin‐like growth factor (IGF2) in ovaries of Rhipicephalus microplus partially engorged females. Ovaries from females at different feeding stages were used to detect IGF2. ABSTRACT Gonadulin and insulin‐like growth factor (IGF) are neuropeptides synthesized by the central nervous system (CNS) of arthropods.
Jéssica Waldman, Lucas Teixeira de Castro, Vinícius Andrade‐Silva, Jéssica Andrade Paes, Luís Fernando Parizi, Maria Aparecida Juliano, Saulo Petinatti Pavarini, David Driemeier, Itabajara da Silva Vaz Jr.   +8 more
wiley   +1 more source