The structure of Plasmodium yoelii merozoite surface protein 119, antibody specificity and implications for malaria vaccine design [PDF]
Open Biology, 2014 Merozoite surface protein 1 (MSP1) has been identified as a target antigen for protective immune responses against asexual blood stage malaria, but effective vaccines based on MSP1 have not been developed so far.
Rachel D. Curd +5 more
doaj +1 more source
In Silico Studies of Four Compounds of Cecropia obtusifolia against Malaria Parasite
Molecules, 2023 Malaria is a disease that affects many people in the world. In Mexico, malaria remains an active disease in certain regions, particularly in the states of Chiapas and Chihuahua.
Carlos Alberto Lobato-Tapia +2 more
doaj +1 more source
Imported Malaria in an Immigrant Toddler Boy in Kashan, a Non-Malaria Endemic Area, Central Iran
Journal of Medical Microbiology and Infectious Diseases, 2022 Malaria is an imported disease in non-endemic regions of Iran. Imported malaria cases to Iran mostly come from illegal immigrants from neighboring eastern countries.
Tayebeh Taghipour1 +3 more
doaj +1 more source
Molecular Mechanisms of Drug Resistance in Plasmodium falciparum Malaria.
Annual Review of Microbiology, 2020 Understanding and controlling the spread of antimalarial resistance, particularly to artemisinin and its partner drugs, is a top priority. Plasmodium falciparum parasites resistant to chloroquine, amodiaquine, or piperaquine harbor mutations in the P ...
Kathryn J. Wicht, Sachel Mok, D. Fidock
semanticscholar +1 more source
Plasmodium Kinases as Potential Drug Targets for Malaria: Challenges and Opportunities
ACS Infectious Diseases, 2021 Protein and phosphoinositide kinases have been successfully exploited as drug targets in various disease areas, principally in oncology. In malaria, several protein kinases are under investigation as potential drug targets, and an inhibitor of Plasmodium
Lauren B. Arendse +3 more
semanticscholar +1 more source
Plasmodium-Host-Plasmodium interactions [PDF]
Malaria Journal, 2010 Plasmodium passage through the skin followed by infection of liver hepatocytes and, later, of blood erythrocytes are natural and sequential steps of Plasmodium life cycle in the mammalian host and should not be seen as independent entities. Importantly, in regions of high malaria transmission, infected individuals are constantly exposed to potential re-
openaire +1 more source
Genomic epidemiology of artemisinin resistant malaria
eLife, 2016 The current epidemic of artemisinin resistant Plasmodium falciparum in Southeast Asia is the result of a soft selective sweep involving at least 20 independent kelch13 mutations.
MalariaGEN Plasmodium falciparum Community Project
doaj +1 more source
Incidence of avian malaria in hummingbirds in humid premontane forests of Pichincha Province, Ecuador: A pilot study [PDF]
Veterinary World, 2021 Background and Aim: Avian malaria is a tropical disease caused by protozoans of the genera Plasmodium and Haemoproteus. As a nonlethal disease, avian malaria can affect the lifespan and reproductive rate of birds.
Claudia S. Abad +3 more
doaj +1 more source
The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015
Nature, 2015 Since the year 2000, a concerted campaign against malaria has led to unprecedented levels of intervention coverage across sub-Saharan Africa. Understanding the effect of this control effort is vital to inform future control planning.
S. Bhatt +31 more
semanticscholar +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance Detection of submicroscopic malaria in asymptomatic individuals is needed for eradication and remains a diagnostic gap in resource-limited settings. Nonfalciparum clinical diagnostics are a second gap, as these infections have a low parasite
Rose A. Lee +9 more
semanticscholar +1 more source