Results 11 to 20 of about 459,674 (351)
Plasmodium—a brief introduction to the parasites causing human malaria and their basic biology
Journal of Physiological Anthropology, 2021 Malaria is one of the most devastating infectious diseases of humans. It is problematic clinically and economically as it prevails in poorer countries and regions, strongly hindering socioeconomic development.
Shigeharu Sato
semanticscholar +1 more source
Plasmodium Kinases as Potential Drug Targets for Malaria: Challenges and Opportunities
ACS Infectious Diseases, 2021 Protein and phosphoinositide kinases have been successfully exploited as drug targets in various disease areas, principally in oncology. In malaria, several protein kinases are under investigation as potential drug targets, and an inhibitor of Plasmodium
Lauren B. Arendse +3 more
semanticscholar +1 more source
Molecular Mechanisms of Drug Resistance in Plasmodium falciparum Malaria.
Annual Review of Microbiology, 2020 Understanding and controlling the spread of antimalarial resistance, particularly to artemisinin and its partner drugs, is a top priority. Plasmodium falciparum parasites resistant to chloroquine, amodiaquine, or piperaquine harbor mutations in the P ...
Kathryn J. Wicht, Sachel Mok, D. Fidock
semanticscholar +1 more source
Avian malaria co-infections confound infectivity and vector competence assays of Plasmodium homopolare. [PDF]
, 2018 Currently, there are very few studies of avian malaria that investigate relationships among the host-vector-parasite triad concomitantly. In the current study, we experimentally measured the vector competence of several Culex mosquitoes for a newly ...
Barker, Christopher M +5 more
core +1 more source
Song sparrows Melospiza melodia have a home-field advantage in defending against sympatric malarial parasites [PDF]
Royal Society Open Science, 2016 Hosts and parasites interact on both evolutionary and ecological timescales. The outcome of these interactions, specifically whether hosts are more resistant to their local parasites (sympatric) than to parasites from another location (allopatric), is ...
Yanina Sarquis-Adamson +1 more
doaj +1 more source
Plasmodium vivax-like genome sequences shed new insights into Plasmodium vivax biology and evolution [PDF]
, 2018 Although Plasmodium vivax is responsible for the majority of malaria infections outside Africa, little is known about its evolution and pathway to humans. Its closest genetic relative, P.
Arnathau, Céline +15 more
core +4 more sources
Genomic epidemiology of artemisinin resistant malaria
eLife, 2016 The current epidemic of artemisinin resistant Plasmodium falciparum in Southeast Asia is the result of a soft selective sweep involving at least 20 independent kelch13 mutations.
MalariaGEN Plasmodium falciparum Community Project
doaj +1 more source
Biomedical and Biotechnology Research Journal, 2020 Background: Gluconeogenesis is stimulated by low blood glucose to maintain the glucose level; it involves lipolysis (breaking down of triglycerides), release of cortisol, and production of glycerol which can be converted into glucose.
Mathew Folaranmi Olaniyan +2 more
doaj +1 more source
The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015
Nature, 2015 Since the year 2000, a concerted campaign against malaria has led to unprecedented levels of intervention coverage across sub-Saharan Africa. Understanding the effect of this control effort is vital to inform future control planning.
S. Bhatt +31 more
semanticscholar +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance Detection of submicroscopic malaria in asymptomatic individuals is needed for eradication and remains a diagnostic gap in resource-limited settings. Nonfalciparum clinical diagnostics are a second gap, as these infections have a low parasite
Rose A. Lee +9 more
semanticscholar +1 more source