Results 11 to 20 of about 15,032 (50)

The Sporozoite's Journey Through the Mosquito: A Critical Examination of Host and Parasite Factors Required for Salivary Gland Invasion

Frontiers in Ecology and Evolution, 2019
Although much progress has been made in the fight against malaria, the number of people that contract this disease due to the bite of an Anopheline mosquito remains unacceptably high.
Bianca B. Kojin, Zach N. Adelman
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Anopheline mosquito saliva contains bacteria that are transferred to a mammalian host through blood feeding

Frontiers in Microbiology, 2023
IntroductionMalaria transmission occurs when Plasmodium sporozoites are transferred from the salivary glands of anopheline mosquitoes to a human host through the injection of saliva. The need for better understanding, as well as novel modes of inhibiting,
Anastasia Accoti, Claudia Damiani, Emilia Nunzi, Alessia Cappelli, Gloria Iacomelli, Giulia Monacchia, Antonella Turco, Francesco D’Alò, Matthew J. Peirce, Guido Favia, Roberta Spaccapelo, Roberta Spaccapelo   +11 more
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Transcriptomic analysis reveals reduced transcriptional activity in the malaria parasite Plasmodium cynomolgi during progression into dormancy

eLife, 2018
Relapses of Plasmodium dormant liver hypnozoites compromise malaria eradication efforts. New radical cure drugs are urgently needed, yet the vast gap in knowledge of hypnozoite biology impedes drug discovery.
Nicole L Bertschi, Annemarie Voorberg-van der Wel, Anne-Marie Zeeman, Sven Schuierer, Florian Nigsch, Walter Carbone, Judith Knehr, Devendra K Gupta, Sam O Hofman, Nicole van der Werff, Ivonne Nieuwenhuis, Els Klooster, Bart W Faber, Erika L Flannery, Sebastian A Mikolajczak, Vorada Chuenchob, Binesh Shrestha, Martin Beibel, Tewis Bouwmeester, Niwat Kangwanrangsan, Jetsumon Sattabongkot, Thierry T Diagana, Clemens HM Kocken, Guglielmo Roma   +23 more
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Glucocorticoid dysfunction in children with severe malaria

Frontiers in Immunology, 2023
IntroductionMalaria remains a widespread health problem with a huge burden. Severe or complicated malaria is highly lethal and encompasses a variety of pathological processes, including immune activation, inflammation, and dysmetabolism.
Leen Vandermosten, Fran Prenen, Balotin Fogang, Pauline Dagneau de Richecour, Sofie Knoops, Christiane Josiane Donkeu, Cathy Doric Piemba Nguefack, Jean-Voisin Taguebue, Paul Koki Ndombo, Bart Ghesquière, Bart Ghesquière, Lawrence Ayong, Philippe E. Van den Steen   +12 more
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On Programmed Cell Death in Plasmodium falciparum: Status Quo

Journal of Tropical Medicine, 2012
Conflicting arguments and results exist regarding the occurrence and phenotype of programmed cell death (PCD) in the malaria parasite Plasmodium falciparum.
Dewaldt Engelbrecht, Pierre Marcel Durand, Thérèsa Louise Coetzer   +2 more
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Potential herd protection against Plasmodium falciparum infections conferred by mass antimalarial drug administrations

eLife, 2019
The global malaria burden has decreased over the last decade and many nations are attempting elimination. Asymptomatic malaria infections are not normally diagnosed or treated, posing a major hurdle for elimination efforts.
Daniel M Parker, Sai Thein Than Tun, Lisa J White, Ladda Kajeechiwa, May Myo Thwin, Jordi Landier, Victor Chaumeau, Vincent Corbel, Arjen M Dondorp, Lorenz von Seidlein, Nicholas J White, Richard J Maude, François Nosten   +12 more
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A high-fat diet protects C57BL/6 mice from Plasmodium berghei ANKA infection in an experimental malaria study

Frontiers in Tropical Diseases, 2023
IntroductionIt is well known that dietary changes have a significant impact on the immune system, and modifications in lipid balance may contribute to disease progression in several cases.
Sara Malaguti Andrade Soares, Ana Cristina Moura Gualberto, Augusto Cesar da Costa, Diego Assis Gonçalves, Jacy Gameiro   +4 more
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Chromatin structure can introduce systematic biases in genome-wide analyses of Plasmodium falciparum [version 2; peer review: 2 approved]

Open Research Europe, 2022
Background: The maintenance, regulation, and dynamics of heterochromatin in the human malaria parasite, Plasmodium falciparum, has drawn increasing attention due to its regulatory role in mutually exclusive virulence gene expression and the silencing of ...
Jessica Bryant, Sebastian Baumgarten
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High prevalence of Plasmodium infection in fighting cocks in Thailand determined with a molecular method

Journal of Veterinary Research, 2022
Avian malaria caused by Plasmodium and the malaria-like parasites of the genus Haemoproteus has been regularly described in multiple regions worldwide. These parasites significantly affect many avian taxa, including domestic chickens and fighting cocks ...
Vaisusuk Kotchaphon, Chatan Wasupon, Seerintra Tossapol, Piratae Supawadee   +3 more
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A Study on the Effect of N-Acetylcysteine on Acute Kidney Injury due to Falciparum Malaria [PDF]

Journal of Clinical and Diagnostic Research, 2021
Introduction: Acute Kidney Injury (AKI) occurs most commonly in Plasmodium falciparum infection. Next to cerebral malaria and anaemia, AKI is the third most common complication of falciparum malaria.
GURUPADA DAS, BIBHU PRASAD BEHERA, PURNA CHANDRA KARUA, RAMA CHANDRA SETHY   +3 more
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