Results 31 to 40 of about 317,079 (354)

The Transcriptome of the Intraerythrocytic Developmental Cycle of Plasmodium falciparum

open access: yesPLoS Biology, 2003
Plasmodium falciparum is the causative agent of the most burdensome form of human malaria, affecting 200–300 million individuals per year worldwide. The recently sequenced genome of P. falciparum revealed over 5,400 genes, of which 60% encode proteins of
Zbynek Bozdech   +5 more
semanticscholar   +1 more source

Towards functional antibody-based vaccines to prevent pre-erythrocytic malaria infection

open access: yesExpert Review of Vaccines, 2017
Introduction: An effective malaria vaccine would be considered a milestone of modern medicine, yet has so far eluded research and development efforts.
Brandon Sack   +2 more
doaj   +1 more source

Three-dimensional ultrastructure of Plasmodium falciparum throughout cytokinesis

open access: yesPLoS Pathogens, 2020
New techniques for obtaining electron microscopy data through the cell volume are being increasingly utilized to answer cell biologic questions. Here, we present a three-dimensional atlas of Plasmodium falciparum ultrastructure throughout parasite cell ...
Rachel M. Rudlaff   +3 more
semanticscholar   +1 more source

A high-fat diet protects C57BL/6 mice from Plasmodium berghei ANKA infection in an experimental malaria study

open access: yesFrontiers in Tropical Diseases, 2023
IntroductionIt is well known that dietary changes have a significant impact on the immune system, and modifications in lipid balance may contribute to disease progression in several cases.
Sara Malaguti Andrade Soares   +4 more
doaj   +1 more source

The Malaria Cell Atlas: Single parasite transcriptomes across the complete Plasmodium life cycle

open access: yesScience, 2019
Mapping the malaria parasite Several species of the parasite Plasmodium cause human malarial diseases, and, despite determined control efforts, a huge global disease burden remains. Howick et al. present a single-cell analysis of transcription across the
Virginia M. Howick   +15 more
semanticscholar   +1 more source

A review on malaria eradication: what hope for Nigeria?

open access: yesJournal of Applied Sciences and Environmental Management, 2016
Malaria and its transmitting vectors are household names. Malaria which helped Africa from the venomous fangs of colonialism has turned to be the bane of development in tropical countries including Nigeria.
E.C. Amadi
doaj   +1 more source

Plasmodium vivax Mimicking Morphologic Features of Plasmodium falciparum [PDF]

open access: yesCureus, 2020
Plasmodium vivax (P. vivax) is the most common cause of malaria in Pakistan. Several cases of severe malaria due to P.vivax have been reported from Pakistan and India, however morphological characteristics of the parasite have been mainly ignored. We present two cases of P.
Ghanchi, Najia   +3 more
openaire   +2 more sources

Possible evidence of gluconeogenesis in Plasmodium- Infected children in relationship with the parasite density

open access: yesBiomedical and Biotechnology Research Journal, 2020
Background: Gluconeogenesis is stimulated by low blood glucose to maintain the glucose level; it involves lipolysis (breaking down of triglycerides), release of cortisol, and production of glycerol which can be converted into glucose.
Mathew Folaranmi Olaniyan   +2 more
doaj   +1 more source

Gut Microbiota Composition Modulates the Magnitude and Quality of Germinal Centers during Plasmodium Infections

open access: yesCell Reports, 2020
Summary: Gut microbiota composition is associated with human and rodent Plasmodium infections, yet the mechanism by which gut microbiota affects the severity of malaria remains unknown.
Morgan L. Waide   +7 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

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