Results 31 to 40 of about 310,877 (350)
eLife, 2018 Relapses of Plasmodium dormant liver hypnozoites compromise malaria eradication efforts. New radical cure drugs are urgently needed, yet the vast gap in knowledge of hypnozoite biology impedes drug discovery.
Nicole L Bertschi +23 more
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In Silico Studies of Four Compounds of Cecropia obtusifolia against Malaria Parasite
Molecules, 2023 Malaria is a disease that affects many people in the world. In Mexico, malaria remains an active disease in certain regions, particularly in the states of Chiapas and Chihuahua.
Carlos Alberto Lobato-Tapia +2 more
doaj +1 more source
Identification of Protein Markers in Patients Infected with Plasmodium knowlesi, Plasmodium falciparum and Plasmodium vivax [PDF]
International Journal of Molecular Sciences, 2014 Malaria is caused by parasitic protozoans of the genus Plasmodium and is one of the most prevalent infectious diseases in tropical and subtropical regions. For this reason, effective and practical diagnostic methods are urgently needed to control the spread of malaria.
Mu, Alan +3 more
openaire +3 more sources
Glucocorticoid dysfunction in children with severe malaria
Frontiers in Immunology, 2023 IntroductionMalaria remains a widespread health problem with a huge burden. Severe or complicated malaria is highly lethal and encompasses a variety of pathological processes, including immune activation, inflammation, and dysmetabolism.
Leen Vandermosten +12 more
doaj +1 more source
A microsporidian impairs Plasmodium falciparum transmission in Anopheles arabiensis mosquitoes
Nature Communications, 2020 A possible malaria control approach involves the dissemination in mosquitoes of inherited symbiotic microbes to block Plasmodium transmission. However, in the Anopheles gambiae complex, the primary African vectors of malaria, there are limited reports of
J. Herren +13 more
semanticscholar +1 more source
eLife, 2019 The global malaria burden has decreased over the last decade and many nations are attempting elimination. Asymptomatic malaria infections are not normally diagnosed or treated, posing a major hurdle for elimination efforts.
Daniel M Parker +12 more
doaj +1 more source
Frontiers in Microbiology, 2023 IntroductionMalaria transmission occurs when Plasmodium sporozoites are transferred from the salivary glands of anopheline mosquitoes to a human host through the injection of saliva. The need for better understanding, as well as novel modes of inhibiting,
Anastasia Accoti +11 more
doaj +1 more source
Trends in Parasitology, 2019 Plasmodium falciparum is the etiological agent of malaria tropica, the leading cause of death due to a vector-borne infectious disease, claiming 0.5 million lives every year. The single-cell eukaryote undergoes a complex life cycle and is an obligate intracellular parasite of hepatocytes (clinically silent) and erythrocytes (disease causing).
Maier, Alex +3 more
openaire +3 more sources
Cell, 2003 The highly A+T rich genomes of human and rodent malarial parasites offer unprecedented glimpses of a lineage that is distinct from other model organisms. Plasmodium is distinguished by the presence of numerous low complexity inserts within globular domains of proteins. It displays several peculiarities in its transcription apparatus, and its DNA repair
Louis H. Miller +3 more
openaire +3 more sources
The structure of Plasmodium yoelii merozoite surface protein 119, antibody specificity and implications for malaria vaccine design [PDF]
Open Biology, 2014 Merozoite surface protein 1 (MSP1) has been identified as a target antigen for protective immune responses against asexual blood stage malaria, but effective vaccines based on MSP1 have not been developed so far.
Rachel D. Curd +5 more
doaj +1 more source