Results 41 to 50 of about 213,023 (194)

Plasmodium malariae and Plasmodium ovale – the ‘bashful’ malaria parasites [PDF]

Trends in Parasitology, 2007
Although Plasmodium malariae was first described as an infectious disease of humans by Golgi in 1886 and Plasmodium ovale identified by Stevens in 1922, there are still large gaps in our knowledge of the importance of these infections as causes of malaria in different parts of the world.
Ivo Mueller, Peter A. Zimmerman, John C. Reeder   +2 more
openaire   +3 more sources

Plasmodium malariae in Bangladesh

Transactions of the Royal Society of Tropical Medicine and Hygiene, 2010
We describe a 32-year-old Bangladeshi male presenting with severe malaria caused by a mono-infection with Plasmodium malariae. Rosetting of infected and uninfected erythrocytes, a putative virulence factor in falciparum malaria, was observed in the blood slide. Severe disease caused by P. malariae is extremely rare.
Naowarat Tanomsing, Wahid Rahman, Kamolrat Silamut, Richard J. Maude, Richard J. Maude, Kesinee Chotivanich, Arjen M. Dondorp, Arjen M. Dondorp, MA Faiz, Amir Hossain   +9 more
openaire   +3 more sources

Analysis of nucleosome positioning landscapes enables gene discovery in the human malaria parasite Plasmodium falciparum. [PDF]

, 2015
BackgroundPlasmodium falciparum, the deadliest malaria-causing parasite, has an extremely AT-rich (80.7 %) genome. Because of high AT-content, sequence-based annotation of genes and functional elements remains challenging.
Bunnik, Evelien M, Le Roch, Karine G, Lonardi, Stefano, Lu, Xueqing Maggie, Nasseri, Sara, Pokhriyal, Neeti   +5 more
core   +2 more sources

Europe's contribution to the evaluation of the use of systemic antimicrobials in the treatment of periodontitis

Periodontology 2000, EarlyView., 2023
Abstract This narrative review celebrates Europe's contribution to the current knowledge on systemically administered antimicrobials in periodontal treatment. Periodontitis is the most frequent chronic noncommunicable human disease. It is caused by dysbiotic bacterial biofilms and is commonly treated with subgingival instrumentation.
David Herrera, Arie Jan van Winkelhoff, Paula Matesanz, Katalina Lauwens, Wim Teughels   +4 more
wiley   +1 more source

Construction of a Plasmodium falciparum Rab-interactome identifies CK1 and PKA as Rab-effector kinases in malaria parasites [PDF]

, 2011
Background information The pathology causing stages of the human malaria parasite Plasmodium falciparum reside within red blood cells that are devoid of any regulated transport system.
Bourdoncle, P., Chandran, S., Dandavate, V., Langsley, G., Meissner, M., Ndjembo-Ezougou, C., Rached, F.B., Talabani, H., Tatu, U., Yera, H.   +9 more
core   +1 more source

Pyronaridine for treatment of Plasmodium ovale and Plasmodium malariae infections [PDF]

Antimicrobial Agents and Chemotherapy, 1997
The clinical efficacy of oral pyronaridine was assessed in 22 symptomatic Cameroonian patients infected with Plasmodium ovale or Plasmodium malariae. All patients were cured on or before day 4. In vitro drug assays confirmed the sensitivity of P. ovale and P. malariae isolates to chloroquine and pyronaridine.
Pascal Ringwald, A Same-Ekobo, Jean Bickii, Leonardo K. Basco   +3 more
openaire   +3 more sources

Cryopreservation of Plasmodium Sporozoites

Pathogens, 2022
Malaria is a deadly disease caused by the parasite, Plasmodium, and impacts the lives of millions of people around the world. Following inoculation into mammalian hosts by infected mosquitoes, the sporozoite stage of Plasmodium undergoes obligate development in the liver before infecting erythrocytes and causing clinical malaria.
Carson Bowers, Lisa Hancox, Kristen Peissig, Justine C. Shiau, Amélie Vantaux, Benoit Witkowski, Sivchheng Phal, Steven P. Maher, John T. Harty, Dennis E. Kyle, Samarchith P. Kurup   +10 more
openaire   +3 more sources

In Vitro Antiplasmodial Activity and Chemical Composition of Combretum aculeatum, a Medicinal Plant From Niger

Chemistry &Biodiversity, EarlyView.
Workflow of current study. ABSTRACT Malaria remains a significant public health challenge in Niger, accounting for 5.6% of global malaria‐related deaths. Local medicinal plants are frequently used as traditional treatments for malaria, although their efficacy and safety are often insufficiently investigated.
Souleymane Magagi Damé, Louis Leclercq, Catherine Vonthron‐Sénécheau, Amadou Tidjani Ilagouma, Sergio Ortiz   +4 more
wiley   +1 more source

Adaptation of translational machinery in malaria parasites to accommodate translation of poly-adenosine stretches throughout its life cycle [PDF]

, 2019
Malaria is caused by unicellular apicomplexan parasites of the ...
Djuranovic, Sergej, Djuranovic, Slavica Pavlovic, Erath, Jessey   +2 more
core   +1 more source

OMIP‐114: A 36‐Color Spectral Flow Cytometry Panel for Detailed Analysis of T Cell Activation and Regulation in Small Human Blood Volumes

Cytometry Part A, EarlyView.
ABSTRACT This 36‐color flow cytometry panel is designed to characterize multiple lymphocyte compartments, with a focus on T cells, their memory subpopulations, and immune checkpoints in human whole blood samples. In clinical settings, the amount of blood available from patients for scientific research is often limited.
Marie‐Theres Thieme‐Ehlert, Thomas Jacobs, Johannes Brandi, Maria Sophia Mackroth   +3 more
wiley   +1 more source