Results 61 to 70 of about 172,513 (208)

The disappearance of malaria from Denmark, 1862–1900

open access: yesThe Economic History Review, EarlyView.
Abstract The reason for malaria's disappearance from northwestern Europe in the early twentieth century has long been discussed but remains an unresolved conundrum. This is partially due to a previous focus on the early modern era, and partially because various theories have never been tested against each other.
Mathias Mølbak Ingholt   +3 more
wiley   +1 more source

Antimalarial potential of Kerala Ayurvedic Water “Pathimugam”

open access: yesJournal of Vector Borne Diseases
Background & objectives: The persistent threat of drug resistant malaria demands new cures. Low prevalence of malaria in the Indian state of Kerala compared with other proximal states led us to explore if there is any traditional practice in Kerala which
Naveen Kumar Kaushik, Dinkar Sahal
doaj   +1 more source

Evaluation of the Anti-Malarial Activity of the Crude Root Extract and Solvent Fraction of Sesamum indicum (Fabaceae)

open access: yesJournal of Experimental Pharmacology, 2023
Fentaw Girmaw, Getachew Ashagrie Department of Pharmacy, College of Health Science, Woldia University, Woldia, EthiopiaCorrespondence: Fentaw Girmaw, Department of Pharmacy, College of Medicine and Health Science, Woldia University, P.O. Box 400, Woldia,
Girmaw F, Ashagrie G
doaj  

The Plasmodium selenoproteome

open access: yesNucleic Acids Research, 2006
The use of selenocysteine (Sec) as the 21st amino acid in the genetic code has been described in all three major domains of life. However, within eukaryotes, selenoproteins are only known in animals and algae. In this study, we characterized selenoproteomes and Sec insertion systems in protozoan Apicomplexa parasites.
Lobanov, Alexey V.   +8 more
openaire   +2 more sources

Evolutionary divergence and functional insights into the heteromeric cis‐prenyltransferase of Paramecium tetraurelia

open access: yesThe FEBS Journal, EarlyView.
Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk   +8 more
wiley   +1 more source

Leishmania donovani's protein tyrosine phosphatases interact with DUF21 and respond to environmental magnesium

open access: yesThe FEBS Journal, EarlyView.
The Leishmania phosphatase PTP1, and possibly the genetically similar PTP2, interacts with the Leishmania transmembrane protein DUF21. When both ptp1 and ptp2 are knocked out of Leishmania (LdΔPTP1/2), the parasite can no longer survive without magnesium in vitro and has reduced viability in the host macrophage. Conversely, in duf21 knockout (LdΔDUF21),
Kayla Paulini   +6 more
wiley   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

open access: yesImmunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude   +2 more
wiley   +1 more source

Potential herd protection against Plasmodium falciparum infections conferred by mass antimalarial drug administrations

open access: yeseLife, 2019
The global malaria burden has decreased over the last decade and many nations are attempting elimination. Asymptomatic malaria infections are not normally diagnosed or treated, posing a major hurdle for elimination efforts.
Daniel M Parker   +12 more
doaj   +1 more source

First Report of ‘Soft Flesh’ Induced by the Parasite Kudoa thyrsites (Myxosporea) in Commercial Codfish From Norway

open access: yesJournal of Fish Diseases, Volume 48, Issue 4, April 2025.
ABSTRACT Kudoa thyrsites is a myxosporean parasite that infects the skeletal muscle of various teleost fish species globally. Severe infections lead to ‘soft flesh’ in fish fillets, resulting in food spoilage and subsequent discard. While K. thyrsites has previously been identified in migratory Atlantic mackerel in the northern Northeast Atlantic Ocean,
Lucilla Giulietti   +6 more
wiley   +1 more source

The Sporozoite's Journey Through the Mosquito: A Critical Examination of Host and Parasite Factors Required for Salivary Gland Invasion

open access: yesFrontiers in Ecology and Evolution, 2019
Although much progress has been made in the fight against malaria, the number of people that contract this disease due to the bite of an Anopheline mosquito remains unacceptably high.
Bianca B. Kojin, Zach N. Adelman
doaj   +1 more source

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