Results 131 to 140 of about 124,584 (310)

Activation of human NK cells by Plasmodium-infected red blood cells.

, 2012
This chapter describes a protocol to assess activation of human NK cells following in vitro stimulation with malaria-infected red blood cells. Activation is assessed by flow cytometry, staining for cell surface expression of CD69 and accumulation of ...
Horowitz, Amir, Riley, Eleanor M
core   +1 more source

MEPicides: Potent antimalarial prodrugs targeting isoprenoid biosynthesis [PDF]

, 2017
The emergence of Plasmodium falciparum resistant to frontline therapeutics has prompted efforts to identify and validate agents with novel mechanisms of action. MEPicides represent a new class of antimalarials that inhibit enzymes of the methylerythritol
Brothers, Robert C, Dowd, Cynthia S, Edwards, Rachel L, Hruz, Paul W, Kraft, Thomas E, Maron, Maxim I, Odom John, Audrey R, Tsang, Patricia S, Wang, Xu, Williamson, Kim C, Ziniel, Peter D   +10 more
core   +2 more sources

Efficacy of a Plasmodium vivax Malaria Vaccine Using ChAd63 and Modified Vaccinia Ankara Expressing Thrombospondin-Related Anonymous Protein as Assessed with Transgenic Plasmodium berghei Parasites

Infection and Immunity, 2013
Plasmodium vivax is the world's most widely distributed malaria parasite and a potential cause of morbidity and mortality for approximately 2.85 billion people living mainly in Southeast Asia and Latin America.
Karolis Bauza, T. Malinauskas, Claudia Pfander, B. Anar, E. Jones, O. Billker, A. Hill, A. Reyes‐Sandoval   +7 more
semanticscholar   +1 more source

Functional profiles of orphan membrane transporters in the life cycle of the malaria parasite [PDF]

, 2016
Assigning function to orphan membrane transport proteins and prioritizing candidates for detailed biochemical characterization remain fundamental challenges and are particularly important for medically relevant pathogens, such as malaria parasites.
Kenthirapalan, Sanketha, Kooij, Taco W. A., Matuschewski, Kai, Waters, Andrew P.   +3 more
core   +4 more sources

THE ACTION OF ANTIMALARIAL DRUGS IN MICE INFECTED WITH PLASMODIUM BERGHEI [PDF]

, 1950
June P. Thurston
openalex   +1 more source

Natural killer cells as an initial defense against pathogens. [PDF]

, 2006
Natural killer (NK) cells serve as a crucial first line of defense against tumors and a diverse range of pathogens. Recognition of infection by NK cells is accomplished by the activation of receptors on the NK cell surface, which initiate NK cell ...
Lanier, Lewis L, Lodoen, Melissa B
core  

In vitro activity and in vivo efficacy of omadacycline against Plasmodium species

Malaria Journal
Background Doxycycline is currently the only tetracycline-class antibiotic recommended for malaria prophylaxis. Omadacycline, a semisynthetic aminomethylcycline approved for treatment of adults with community-acquired bacterial pneumonia and acute ...
Michael S. Madejczyk, Susan E. Leed, Karl Kudyba, Alison Roth, Monica L. Martin, Patricia Lee, Diane Anastasiou, Jessica V. Pierce, Alisa W. Serio, Diana Caridha   +9 more
doaj   +1 more source

The metabolism of Plasmodium berghei, the malaria parasite of rodents. 2. An effect of mepacrine on the metabolism of glucose by the parasite separated from its host cell [PDF]

, 1961
I.B.R. Bowman, P. T. Grant, W. O. Kermack, D. Ogston   +3 more
openalex   +1 more source

Infections en série par le Plasmodium berghei de Souris blanches traitées [PDF]

, 1966
J. Sautet, R Dupoux, J Fondarai, J Aldighieri, A. Blancard, N Boizis   +5 more
openalex   +1 more source

Estudo preliminar sôbre a localização renal de complexos antígeno-anticorpo em ratos infectados com plasmodium berghei [PDF]

, 1969
Carlos Eduardo Tosta
openalex   +1 more source