Results 111 to 120 of about 18,594 (231)

The liver stage of Plasmodium berghei inhibits host cell apoptosis.

, 2005
Plasmodium berghei is the causative agent of rodent malaria and is widely used as a model system to study the liver stage of Plasmodium parasites. The entry of P.
Stefanie Bolte, HORSTMANN, S, Andreas Krueger, BOLTE, S, KRUEGER, A, Sturm, Angelika, Bolte, Stefanie, HEUSSLER, VT, Lütgehetmann, Marc, Claudia van de Sand, Anja Schmidt, Marc Lütgehetmann, Krueger, Andreas, POLLOK, JM, STURM, A, van de Sand, Claudia, Horstmann, Sebastian, Libert, Claude, Sebastian Horstmann, Heussler, Volker, SCHMIDT, A, Jörg‐Matthias Pollok, Claude Libert, Volker T. Heussler, Schmidt, Anja, LUTGEHETMANN, M, Pollok, Jörg-Matthias, Angelika Sturm, VAN DE SAND, C   +28 more
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Neuroprotective and antimalarial effects of Juglans regia leaf extracts in a murine model of cerebral malaria

Frontiers in Veterinary Science
BackgroundMalaria is a major public health problem caused by the apicomplexan Plasmodium parasite. Cerebral malaria (CM) is the most critical outcome of Plasmodium infection.
Afra Alharbi, Shurug Albasyouni, Esam Al-Shaebi, Saleh Al Quraishy, Rewaida Abdel-Gaber   +4 more
doaj   +1 more source

Signatures of malaria vaccine efficacy in ageing murine immune memory.

, 2014
Malaria transmission occurs by mosquito bite. Thereafter, Plasmodium sporozoites specifically invade the liver, where they develop into thousands of merozoites that initiate blood-stage infection and clinical malaria.
Kooij, TWA, Hafalla, J.C., Kooij, T., Hafalla, JCR, Matuschewski, K, Burgold, J, Matuschewski, K., Haussig, J.M., Hafalla, J., Kooij, T.W.A., Burgold, J., Haussig, JM, Haussig, J.   +12 more
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Natural immunization against malaria: causal prophylaxis with antibiotics.

, 2010
Malaria remains the most prevalent vector-borne infectious disease and has the highest rates of fatality. Current antimalarial drug strategies cure malaria or prevent infections but lack a sustained public health impact because they fail to expedite the ...
Hafalla, Julius C. R., Friesen, J., Kai Matuschewski, Hafalla, Julius CR, Borrmann, S., Friesen, Johannes, Julius C. R. Hafalla, Elyzana Dewi Putrianti, Matuschewski, K., Hafalla, J., Matuschewski, Kai, Putrianti, E., Silvie, Olivier, Putrianti, Elyzana Dewi, Borrmann, Steffen, Johannes Friesen, Olivier Silvie, Steffen Borrmann, Silvie, O.   +18 more
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Multi-system dysregulation in placental malaria contributes to adverse perinatal outcomes in mice

Infection and Immunity
Sequestration of Plasmodium parasites in the placental vasculature contributes to increased morbidity and mortality in pregnant compared to non-pregnant patients in malaria-endemic regions.
Phebe Ekregbesi, Brittany Seibert, Maclaine A. Parish, Yevel Flores-Garcia, Patrick S. Creisher, Joseph P. Hoffmann, Jennifer A. Liu, Cory Brayton, Fidel Zavala, Sabra L. Klein   +9 more
doaj   +1 more source

Improved synchronous production of Plasmodium falciparum gametocytes in vitro.

, 2007
The sexual stages of the Plasmodium falciparum life cycle are attractive targets for vaccines and transmission blocking drugs. Difficulties in culturing and obtaining large amounts of sexual stage P.
Sutherland, Colin J, Baker, David A, Sharp, Sarah, Taylor, Cathy J, McRobert, Louisa, Fivelman, Quinton L, Swales, Claire A, Saeed, Maha   +7 more
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Ajuvant effect of a Synthetic Aluminium - Magnesium Silicate on chloroquine phosphate, against Plasmodium berghei.

, 2012
effect of a synthetic Aluminium - Magnesium Silicate (AMS) on antiplasmodial activity of chloroquine was tested. Plasmodium berghei-infected mice were treated with 7 mg/kg, 5 mg/kg and 3 mg/kg chloroquine, respectively.
obianuju obianuju Okoroafor, nnenna elendu-eleke, Augustine Ngene, madike ezeibe   +3 more
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Efficient development of plasmodium liver stage-specific memory CD8+ T cells during the course of blood-stage malarial infection.

, 2007
Immunity to Plasmodium liver stages in individuals in malaria-endemic areas is inextricably linked to concomitant blood-stage parasitemia. Although Plasmodium sporozoite infection induces measurable CD8+ T cell responses, the development of memory T ...
Dabeiba Bernal‐Rubio, Rai, Urvashi, Julius C. R. Hafalla, Fidel Zavala, Hafalla, Julius CR, Rodriguez, Ana, Ana Rodriguez, Zavala, Fidel, Urvashi Rai, Bernal-Rubio, Dabeiba   +9 more
core   +1 more source

Migration through host cells activates Plasmodium sporozoites for infection.

, 2002
Plasmodium sporozoites, the infective stage of the malaria parasite transmitted by mosquitoes, migrate through several hepatocytes before infecting a final one. Migration through hepatocytes occurs by breaching their plasma membranes, and final infection
Hafalla, Julius CR, Rodriguez, Ana, Ana Rodriguez, Mota, Maria M, Julius C.R. Hafalla, Maria M. Mota   +5 more
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The effect of quinoline anti-malarial drugs on the endolysosomal and secretory pathways of plasmodium falciparum strain 3D7, dictyostelium discoideum and mammalian A549 cells

, 2007
Includes bibliographical references (leaves 92-109).The precise mechanisms of action of the quinoline anti-malarial drugs are uncertain, although they have been found to influence endocytosis, vesicular processing and secretion in malarial parasites and ...
Roberts, Lindi
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