Results 101 to 110 of about 90,646 (224)

Protists show high resilience and thrive under multiple chemical stressors

mLife, Volume 5, Issue 3, Page 388-392, June 2026.
Jijuan Ding, Fei Liu, Yuanchen Zhao, Zhili He, Yijing Shi, Longfei Shu   +5 more
wiley   +1 more source

Malarone treatment failure and in vitro confirmation of resistance of Plasmodium falciparum isolate from Lagos, Nigeria. [PDF]

, 2002
We report the first in vitro and genetic confirmation of Malarone (GlaxoSmithKline; atovaquone and proguanil hydrochloride) resistance in Plasmodium falciparum acquired in Africa.
Fivelman, Quinton L, Pasvol Geoffrey, Adagu Ipemida S, Butcher, Geoffrey A, Adagu, Ipemida S, Warhurst David C, Butcher Geoffrey A, David C Warhurst, Geoffrey Pasvol, Quinton L Fivelman, Warhurst, David C, Fivelman Quinton L, Pasvol, Geoffrey, Ipemida S Adagu, Beier, John, Geoffrey A Butcher   +15 more
core   +1 more source

Prospective identification of malaria parasite genes under balancing selection. [PDF]

, 2009
BACKGROUND: Endemic human pathogens are subject to strong immune selection, and interrogation of pathogen genome variation for signatures of balancing selection can identify important target antigens.
Conway, David J, Lynette Isabella Ochola, Amambua-Ngwa, A, Ochola, LI, Tetteh, Kevin KA, Stewart Lindsay B., Kevin Marsh, Thomas Alan W., Lindsay B Stewart, Alfred Amambua-Ngwa, David J Conway, Gareth D Weedall, Tetteh, KK, Kevin K A Tetteh, Weedall, Gareth D, Conway David J., Marsh Kevin, Weedall Gareth D., Marsh, K, Conway, DJ, Ochola Lynette Isabella, Tetteh Kevin K. A., Stewart, LB, Amambua-Ngwa, Alfred, Weedall, GD, Thomas, AW, Ochola, Lynette Isabella, Stewart, Lindsay B, Thomas, Alan W, Alan W Thomas, Amambua-Ngwa Alfred, Marsh, Kevin   +31 more
core   +1 more source

Construction of a Plasmodium falciparum Rab-interactome identifies CK1 and PKA as Rab-effector kinases in malaria parasites [PDF]

, 2011
Background information The pathology causing stages of the human malaria parasite Plasmodium falciparum reside within red blood cells that are devoid of any regulated transport system.
Tatu, Utpal, Yera, H., Yera, Helene, Talabani, Hana, Talabani, H., Dandavate, V., Dandavate, Vrushali, Langsley, Gordon, Tatu, U., Langsley, G., Bourdoncle, P., Meissner, M., Ben Rached, Fathia, Ndjembo-Ezougou, Carinne, Rached, F.B., Chandran, S., Chandran, Syama, Ndjembo-Ezougou, C., Bourdoncle, Pierre, Meissner, Markus   +19 more
core   +1 more source

In vitro activity and in vivo efficacy of omadacycline against Plasmodium species

Malaria Journal
Background Doxycycline is currently the only tetracycline-class antibiotic recommended for malaria prophylaxis. Omadacycline, a semisynthetic aminomethylcycline approved for treatment of adults with community-acquired bacterial pneumonia and acute ...
Michael S. Madejczyk, Susan E. Leed, Karl Kudyba, Alison Roth, Monica L. Martin, Patricia Lee, Diane Anastasiou, Jessica V. Pierce, Alisa W. Serio, Diana Caridha   +9 more
doaj   +1 more source

Ajuvant effect of a Synthetic Aluminium - Magnesium Silicate on chloroquine phosphate, against Plasmodium berghei. [PDF]

, 2012
effect of a synthetic Aluminium - Magnesium Silicate (AMS) on antiplasmodial activity of chloroquine was tested. Plasmodium berghei-infected mice were treated with 7 mg/kg, 5 mg/kg and 3 mg/kg chloroquine, respectively.
obianuju obianuju Okoroafor, nnenna elendu-eleke, Augustine Ngene, madike ezeibe   +3 more
core  

The effect of quinoline anti-malarial drugs on the endolysosomal and secretory pathways of plasmodium falciparum strain 3D7, dictyostelium discoideum and mammalian A549 cells [PDF]

, 2007
Includes bibliographical references (leaves 92-109).The precise mechanisms of action of the quinoline anti-malarial drugs are uncertain, although they have been found to influence endocytosis, vesicular processing and secretion in malarial parasites and ...
Roberts, Lindi
core   +1 more source

Neuroprotective and antimalarial effects of Juglans regia leaf extracts in a murine model of cerebral malaria

Frontiers in Veterinary Science
BackgroundMalaria is a major public health problem caused by the apicomplexan Plasmodium parasite. Cerebral malaria (CM) is the most critical outcome of Plasmodium infection.
Afra Alharbi, Shurug Albasyouni, Esam Al-Shaebi, Saleh Al Quraishy, Rewaida Abdel-Gaber   +4 more
doaj   +1 more source

Multi-system dysregulation in placental malaria contributes to adverse perinatal outcomes in mice

Infection and Immunity
Sequestration of Plasmodium parasites in the placental vasculature contributes to increased morbidity and mortality in pregnant compared to non-pregnant patients in malaria-endemic regions.
Phebe Ekregbesi, Brittany Seibert, Maclaine A. Parish, Yevel Flores-Garcia, Patrick S. Creisher, Joseph P. Hoffmann, Jennifer A. Liu, Cory Brayton, Fidel Zavala, Sabra L. Klein   +9 more
doaj   +1 more source

Signatures of malaria vaccine efficacy in ageing murine immune memory.

, 2014
Malaria transmission occurs by mosquito bite. Thereafter, Plasmodium sporozoites specifically invade the liver, where they develop into thousands of merozoites that initiate blood-stage infection and clinical malaria.
Kooij, TWA, Hafalla, J.C., Kooij, T., Hafalla, JCR, Matuschewski, K, Burgold, J, Matuschewski, K., Haussig, J.M., Hafalla, J., Kooij, T.W.A., Burgold, J., Haussig, JM, Haussig, J.   +12 more
core   +1 more source