Results 101 to 110 of about 18,594 (231)

Extracellular ATP triggers proteolysis and cytosolic Ca²⁺ rise in Plasmodium berghei and Plasmodium yoelii malaria parasites

Malaria Journal, 2012
Background Plasmodium has a complex cell biology and it is essential to dissect the cell-signalling pathways underlying its survival within the host. Methods Using the fluorescence resonance energy transfer (FRET) peptide substrate Abz-AIKFFARQ-EDDnp and
Cruz Laura, Juliano Maria, Budu Alexandre, Juliano Luiz, Holder Anthony A, Blackman Michael J, Garcia Célia RS   +6 more
doaj   +1 more source

Antiplasmodial Effect of Anthocleista vogelii on Albino Mice Experimentally Infected with Plasmodium berghei berghei (NK 65)

Journal of Parasitology Research, 2014
The objective of the present study was to investigate the antiplasmodial effect of the ethanolic stem bark extract of Anthocleista vogelii at different doses in albino mice infected with Plasmodium berghei berghei (NK 65).
Lebari Barine Gboeloh, Okpok Eta Okon, Samuel Effiong Udoh   +2 more
doaj   +1 more source

Resisting infection by Plasmodium berghei increases the sensitivity of the malaria vector Anopheles gambiae to DDT [PDF]

, 2015
BACKGROUND The evolution of insecticide resistance threatens current malaria control methods, which rely heavily on chemical insecticides. The magnitude of the threat will be determined by the phenotypic expression of resistance in those mosquitoes ...
Paul-Christian Burda, Adam Saddler, Koella, Jacob C, Jacob C Koella, Saddler, Adam, Burda, Paul-Christian   +5 more
core   +1 more source

In Vitro and In Vivo Antimalarial Activity of LZ1, a Peptide Derived from Snake Cathelicidin

Toxins, 2019
Antimalarial drug resistance is an enormous global threat. Recently, antimicrobial peptides (AMPs) are emerging as a new source of antimalarials. In this study, an AMP LZ1 derived from snake cathelicidin was identified with antimalarial activity.
Yaqun Fang, Xiaoqin He, Pengcheng Zhang, Chuanbin Shen, James Mwangi, Cheng Xu, Guoxiang Mo, Ren Lai, Zhiye Zhang   +8 more
doaj   +1 more source

Screening of Traditionally Used Plants for in Vivo Antimalarial Activity in Mice. [PDF]

, 2009
Aqueous ethanol (80%) extracts of six plants used traditionally for treatment of malaria, Vepris glomerata (F.Hoffm.) Engl (Rutaceae), Maranthus floribunda (Bak.) F.White (Chrysobalanaceae), Strophanthus eminii Asch.
Mbwambo, Zakaria H., Kapingu, Modest C., P Masimba, Masimba, Pax J., Mbwambo, Zakaria H, Moshi, M.J., Moshi, M, Kamuhabwa, A, M Moshi, E Innocent, Innocent, E., Innocent, E, Masimba, P, Kapingu, M, Kamuhabwa, A., Kapingu, M.C., Moshi, Mainen J., Masimba, Pax J, Moshi, Mainen J, Kamuhabwa, Appolinary, Mbwambo, Z, A Kamuhabwa, M Kapingu, Innocent, Esther, Mbwambo, Z.H., Kapingu, Modest C, Masimba, P.J., Z Mbwambo   +27 more
core   +1 more source

IL35 modulation altered survival, cytokine environment and histopathological consequences during malaria infection in mice

Malaria Journal, 2019
Background The immune modulating potential of IL-35 in multiple human disorders has been reported. Consequent upon the recognition of inflammatory cytokine activation and its preponderance for mediating pathology during malaria infection, the study aimed
Ramatu Omenesa Bello, Maizaton Atmadini Abdullah, Roslaini Abd Majid, Voon Kin Chin, Mohammed Faruq Abd Rachman Isnadi, Zaid Osama Ibraheem, Mohd Khairi Hussain, Mohammed Garba Magaji, Rusliza Basir   +8 more
doaj   +1 more source

In vitro activity and in vivo efficacy of omadacycline against Plasmodium species

Malaria Journal
Background Doxycycline is currently the only tetracycline-class antibiotic recommended for malaria prophylaxis. Omadacycline, a semisynthetic aminomethylcycline approved for treatment of adults with community-acquired bacterial pneumonia and acute ...
Michael S. Madejczyk, Susan E. Leed, Karl Kudyba, Alison Roth, Monica L. Martin, Patricia Lee, Diane Anastasiou, Jessica V. Pierce, Alisa W. Serio, Diana Caridha   +9 more
doaj   +1 more source

Expression and processing of Plasmodium berghei SERA3 during liver stages.

, 2008
Cysteine proteases mediate liberation of Plasmodium berghei merozoites from infected hepatocytes. In an attempt to identify the responsible parasite proteases, we screened the genome of P. berghei for cysteine protease-encoding genes.
Horstmann, Sebastian, Schmidt-Christensen, Anja, Heussler, Volker, Sturm, Angelika   +3 more
core   +1 more source

Plasmodium alveolins possess distinct but structurally and functionally related multi-repeat domains. [PDF]

, 2014
The invasive and motile life stages of malaria parasites (merozoite, ookinete and sporozoite) possess a distinctive cortical structure termed the pellicle.
Tremp, Annie Z, Al-Khattaf, Fatimah S, Dessens, Johannes T, Fatimah S. Al-Khattaf, Annie Z. Tremp, Johannes T. Dessens   +5 more
core   +1 more source

In vitro cellular studies on the human immune response to plasmodium falciparum malaria [PDF]

, 1983
This thesis was submitted for the degree of Doctor of Philosophy and was awarded by Brunel University.This thesis reports the results of a large number of experiments which were designed to elucidate the mechanisms whereby Gambian children, suffering ...
Brown, James
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