Results 81 to 90 of about 90,646 (224)

A conserved protein of Babesia microti elicits partial protection against Babesia and Plasmodium infection

Parasites & Vectors, 2023
Background The protozoan parasite Babesia microti that causes the zoonotic disease babesiosis resides in the erythrocytes of its mammalian host during its life-cycle.
Yao Wang, Qianqian Zhang, Wanruo Zhang, Junhu Chen, Jianfeng Dai, Xia Zhou   +5 more
doaj   +1 more source

Single‐Cell Transcriptomics and Development of Gametocyte‐Specific Molecular Markers for Avian Malaria Parasites

Molecular Ecology Resources, Volume 26, Issue 5, July 2026.
ABSTRACT Avian malaria, caused by Plasmodium parasites, poses a significant threat to bird populations worldwide, particularly in vulnerable island ecosystems. Yet, progress in understanding avian malaria transmission dynamics has been hampered by the lack of molecular tools to quantify and sex the transmissible stages of the parasite: the male and ...
A. Berthomieu, I. Rizos, J. W. Bagnoli, S. Gandon, A. M. Talman, A. Rivero   +5 more
wiley   +1 more source

Hemoglobin Digestion Genes Are Conserved in Lizard‐Infective Plasmodium Species With Different Host Cellular Niches

Ecology and Evolution, Volume 16, Issue 6, June 2026.
Despite their evolutionary relatedness to malaria parasites that infect humans, wildlife Plasmodium—particularly those that infect birds and lizards—are understudied, leaving their vast genetic diversity to be explored. By assembling parasite transcriptomes from Plasmodium‐infected lizard blood, we provide the first evidence that lizard‐infective ...
Sarah J. Pangburn, Janus Borner, Sidhanth Misra, Jessica Zavalunova, Susan L. Perkins   +4 more
wiley   +1 more source

Investigation of Ethylene Oxide Genotoxicity Dose–Response to Inform Cancer Risk Assessment

Environmental and Molecular Mutagenesis, Volume 67, Issue 5-7, June‐August 2026.
ABSTRACT Ethylene oxide (EtO) is primarily used as an intermediate in the manufacture of chemicals, with a minor use as a sterilant for medical equipment and food products. It is a direct‐acting alkylating agent that reacts with cellular macromolecules, including proteins and DNA. EtO has been shown to induce tumors in rodents and humans.
B. Bhaskar Gollapudi, James E. Bus, Phillip Cassidy, Jeffrey T. Weinberg, Jeffrey C. Bemis, Dorothea K. Torous, Stephen D. Dertinger, Kun Lu, Richard Reiss, Abby A. Li   +9 more
wiley   +1 more source

The CTLA-4 and PD-1/PD-L1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology. [PDF]

, 2012
The balance between pro-inflammatory and regulatory immune responses in determining optimal T cell activation is vital for the successful resolution of microbial infections.
Couper, Kevin N, Claser, C, Riley, Eleanor M, Julius Clemence R Hafalla, Eleanor M Riley, Kevin N Couper, de Souza, J Brian, de Souza, J. Brian, Claser Carla, Renia L., Kevin N. Couper (25399), Grau, GE, Hafalla Julius Clemence R., Laurent Renia (63769), Couper, KN, Hafalla, Julius Clemence R, Grau G.E., Couper Kevin N., Grau, Georges Emile, de Souza, JB, Riley Eleanor M., J. Brian de Souza (25406), Claser C., Renia Laurent, Riley E.M., Hafalla J.C.R., Julius Clemence R. Hafalla (185909), de Souza J.B., de Souza J. Brian, Hafalla, JC, Riley, Eleanor M., Couper K.N., Renia, Laurent, Carla Claser, Georges Emile Grau, Carla Claser (185910), Couper, Kevin N., Georges Emile Grau (185911), Renia, L, Riley, EM, J Brian de Souza, Eleanor M. Riley (25407), Grau Georges Emile, Laurent Renia, Claser, Carla   +44 more
core   +1 more source

Methanol Extract of Ficus trigonata Stem Bark Demonstrated Antiplasmodial Activity in Mice

Baghdad Journal of Biochemistry and Applied Biological Sciences
Malaria, caused by Plasmodium parasites, remains a global health concern, with drug resistance complicating control efforts. Plant-derived compounds have emerged as potential antimalarial agents.
Suleiman mahmoud Jada, Yusuf Umar, Abdullahi Usman Wurochekke   +2 more
doaj   +1 more source

Crystal structure of Plasmodium vivax macrophage migration inhibitory factor

Acta Crystallographica Section F, Volume 82, Issue 6, Page 194-200, June 2026.
The production, crystallization and 1.8 Å resolution crystal structure of macrophage migratory inhibitory factor from P. vivax are reported.Plasmodium vivax is a major cause of malaria globally and has recently been transmitted locally in the USA. P. vivax produces homologs of host proteins, including cytokines such as macrophage migration inhibitory ...
Aryana Nair, Matthew Lin, Arav Srivastava, Lijun Liu, Anne Cooper, Kevin Battaile, Elizabeth Harmon, Peter J. Myler, Bart L. Staker, Scott Lovell, Graham Chakafana, Oluwatoyin A. Asojo   +11 more
wiley   +1 more source

Improved negative selection protocol for Plasmodium berghei in the rodent malarial model [PDF]

, 2012
An improved methodology is presented here for transgenic Plasmodium berghei lines that express the negative selectable marker yFCU (a bifunctional protein that combines yeast cytosine deaminase and uridyl phosphoribosyl transferase (UPRT)) and ...
Nisha Philip, Philip Nisha, Waters Andrew P, Orr Rachael Y, Rachael Y Orr, Orr, R.Y., Waters, A.P., Orr, Rachael Y, Waters, Andrew P, Philip, N., Philip, Nisha, Andrew P Waters   +11 more
core   +1 more source

The phosphatase inhibitor BVT-948 can be used to efficiently screen functional sexual development proteins in the malaria parasite Plasmodium berghei

International Journal for Parasitology: Drugs and Drug Resistance
Background: Studying and discovering the molecular mechanism of Plasmodium sexual development is crucial for the development of transmission blocking drugs and malaria eradication.
Xitong Jia, Yong Wang, Meilian Wang, Hui Min, Zehou Fang, Haifeng Lu, Jiao Li, Yaming Cao, Lunhao Bai, Jinghan Lu   +9 more
doaj   +1 more source

Unravelling the biochemical aspects of the interaction between ticks and Leishmania using a tick cell line

Medical and Veterinary Entomology, Volume 40, Issue 2, Page 350-359, June 2026.
Leishmania infantum propagated in IDE8 tick cell line in vitro. L. infantum reduces tick cell viability and induces reactive oxygen species production. Lipidic profile of IDE8 tick cell line is altered during Leishmania infection. Abstract Leishmaniasis comprises a group of vector‐borne neglected tropical diseases caused by species of the obligatory ...
Beatriz Filgueiras Silvestre, Karoline dos Anjos Lima, Fernanda de Paula Pepino, Daniela Cosentino‐Gomes, Adivaldo Fonseca, Lesley Bell‐Sakyi, Georgia Correa Atella, Lucia H. Pinto‐da‐Silva   +7 more
wiley   +1 more source