Results 61 to 70 of about 12,801 (184)

Methanol Extract of Ficus trigonata Stem Bark Demonstrated Antiplasmodial Activity in Mice

Baghdad Journal of Biochemistry and Applied Biological Sciences
Malaria, caused by Plasmodium parasites, remains a global health concern, with drug resistance complicating control efforts. Plant-derived compounds have emerged as potential antimalarial agents.
Suleiman mahmoud Jada, Yusuf Umar, Abdullahi Usman Wurochekke   +2 more
doaj   +1 more source

A Narrative Review of Antioxidant, Anti‐Inflammatory, Anti‐Apoptotic, Immunomodulatory, and Anticancer Properties of Rosa damascena Mill.

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Rosa damascena Mill. exhibits a broad spectrum of pharmacological activities mediated by its rich phytochemical profile. The plant enhances antioxidant defenses by increasing endogenous enzymes (CAT, SOD, GSH, GST, GPx, FRAP) and reducing oxidative stress markers (MDA, MPO).
Mahboobeh Ghasemzadeh Rahbardar, Nikta Soltani, Mohammad Hossein Boskabady   +2 more
wiley   +1 more source

The phosphatase inhibitor BVT-948 can be used to efficiently screen functional sexual development proteins in the malaria parasite Plasmodium berghei

International Journal for Parasitology: Drugs and Drug Resistance
Background: Studying and discovering the molecular mechanism of Plasmodium sexual development is crucial for the development of transmission blocking drugs and malaria eradication.
Xitong Jia, Yong Wang, Meilian Wang, Hui Min, Zehou Fang, Haifeng Lu, Jiao Li, Yaming Cao, Lunhao Bai, Jinghan Lu   +9 more
doaj   +1 more source

Helminths as architects of trained tolerance: implications for human health

Clinical &Translational Immunology, Volume 15, Issue 3, 2026.
Abstract Helminths infect nearly 2 billion people worldwide and are a major cause of chronic morbidity in low‐resource regions. Unlike bacterial and viral pathogens that elicit protective memory, helminths actively remodel host immunity to enable their years‐long persistence and reinfection.
Quinn Moroz, Jorge Lucas Nascimento Souza, Neima Briggs   +2 more
wiley   +1 more source

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, Volume 36, Issue 11, 5 February 2026.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

Antiplasmodial Effect of Anthocleista vogelii on Albino Mice Experimentally Infected with Plasmodium berghei berghei (NK 65)

Journal of Parasitology Research, 2014
The objective of the present study was to investigate the antiplasmodial effect of the ethanolic stem bark extract of Anthocleista vogelii at different doses in albino mice infected with Plasmodium berghei berghei (NK 65).
Lebari Barine Gboeloh, Okpok Eta Okon, Samuel Effiong Udoh   +2 more
doaj   +1 more source

Protists show high resilience and thrive under multiple chemical stressors

mLife, Volume 5, Issue 3, Page 388-392, June 2026.
Jijuan Ding, Fei Liu, Yuanchen Zhao, Zhili He, Yijing Shi, Longfei Shu   +5 more
wiley   +1 more source

Extracellular ATP triggers proteolysis and cytosolic Ca²⁺ rise in Plasmodium berghei and Plasmodium yoelii malaria parasites

Malaria Journal, 2012
Background Plasmodium has a complex cell biology and it is essential to dissect the cell-signalling pathways underlying its survival within the host. Methods Using the fluorescence resonance energy transfer (FRET) peptide substrate Abz-AIKFFARQ-EDDnp and
Cruz Laura, Juliano Maria, Budu Alexandre, Juliano Luiz, Holder Anthony A, Blackman Michael J, Garcia Célia RS   +6 more
doaj   +1 more source

IL35 modulation altered survival, cytokine environment and histopathological consequences during malaria infection in mice

Malaria Journal, 2019
Background The immune modulating potential of IL-35 in multiple human disorders has been reported. Consequent upon the recognition of inflammatory cytokine activation and its preponderance for mediating pathology during malaria infection, the study aimed
Ramatu Omenesa Bello, Maizaton Atmadini Abdullah, Roslaini Abd Majid, Voon Kin Chin, Mohammed Faruq Abd Rachman Isnadi, Zaid Osama Ibraheem, Mohd Khairi Hussain, Mohammed Garba Magaji, Rusliza Basir   +8 more
doaj   +1 more source

In Vitro and In Vivo Antimalarial Activity of LZ1, a Peptide Derived from Snake Cathelicidin

Toxins, 2019
Antimalarial drug resistance is an enormous global threat. Recently, antimicrobial peptides (AMPs) are emerging as a new source of antimalarials. In this study, an AMP LZ1 derived from snake cathelicidin was identified with antimalarial activity.
Yaqun Fang, Xiaoqin He, Pengcheng Zhang, Chuanbin Shen, James Mwangi, Cheng Xu, Guoxiang Mo, Ren Lai, Zhiye Zhang   +8 more
doaj   +1 more source