Results 41 to 50 of about 12,801 (184)

Plasmodium berghei calcium dependent protein kinase 1 is not required for host cell invasion. [PDF]

PLoS ONE, 2013
Plasmodium Calcium Dependent Protein Kinase (CDPK1) is required for the development of sexual stages in the mosquito. In addition, it is proposed to play an essential role in the parasite's invasive stages possibly through the regulation of the ...
Sylvia Jebiwott, Kavitha Govindaswamy, Amos Mbugua, Purnima Bhanot   +3 more
doaj   +1 more source

Quantitative electroencephalographic measures during postmalarial epileptogenesis

Epilepsia, Volume 67, Issue 7, Page 3602-3611, July 2026.
Abstract Objective Severe malaria with neurologic involvement contributes significantly to the global burden of acquired pediatric epilepsy. We studied quantitative electroencephalographic (EEG) measures in postmalarial epileptogenesis. Methods A total of 186 patients, aged 6 months to 11 years, with confirmed central nervous system malaria were ...
Rasesh B. Joshi, Suzanna Mwanza, Hitten P. Zaveri, Joseph Kasolo, Angela Masempela, Thelma Musakanya, Tina Mwale, Violet Nambeye, Rosemary Nyriongo, Ruth A. Tembo, Christopher Cortina, Bo Zhang, Gretchen L. Birbeck, Alexander Rotenberg, Archana A. Patel   +14 more
wiley   +1 more source

Gambaran Histopatologi Hepar Mencit (Mus musculus Balb/C) yang Diinfeksi dengan Plasmodium berghei

Jurnal Ilmu Kesehatan Indonesia, 2022
Background: The most common cause of death by malaria in Indonesia is Plasmodium falciparum, which is analogous to Plasmodium berghei, which lives as a parasite in the liver of mice.
Hanifah Putri Dwiridal, Adrial Adrial, Eryati Darwin   +2 more
doaj   +1 more source

Genetic recombination in Plasmodium berghei

Parasitology, 1973
Crosses have been made between two lines of Plasmodium berghei yoelii differing in drug-sensitivity and enzyme-type. The two lines used were line A, which is pyrimethamine-resistant and contains an electrophoretic form of glucose phosphate isomerase termed GPI-1, and line C, which is pyrimethamine-sensitive and contains enzyme-form GPI-2. Equal numbers
D, Walliker, R, Carter, S, Morgan
openaire   +2 more sources

Curcumin‐Loaded Nanocapsules: Population Pharmacokinetic and Time‐to Event Modeling in Healthy Rats and LPS‐Induced Inflammation Flies

Nano Select, Volume 7, Issue 7, July 2026.
ABSTRACT Curcumin (CUR) is a bioactive compound with antioxidant, anti‐inflammatory, and anticancer properties, though its clinical use is limited by low bioavailability, rapid metabolism, and poor solubility. To address these challenges, our study investigates nanoencapsulated curcumin (NC‐CUR) to enhance its pharmacokinetics and therapeutic efficacy,
Ana Pozzato Funghetto‐Ribeiro, Camila Pacheco, Flávia Teixeira, Joane Ferreira, Vitória Gallarreta, Clémence Boivin‐Champeaux, Eliana Fernandes, Gustavo Guerra, Francine Azeredo, Sandra Elisa Haas   +9 more
wiley   +1 more source

Immunological Interactions Between Gammadelta T Cells and West Nile Virus in the Infected Host

Reviews in Medical Virology, Volume 36, Issue 4, July 2026.
ABSTRACT Between mosquitoes and birds, West Nile virus (WNV) is a neurotropic flavivirus, an arthropod‐borne pathogen involved in an enzootic cycle. Additionally, it can infect both people and horses, leading to severe illness. Since 1999, WNV has spread across North and South America, including Mexico and the Caribbean.
E. Cimini, E. Tartaglia, F. Cristofanelli, S. Gili, F. Maggi   +4 more
wiley   +1 more source

Chromosome translocation inPlasmodium berghei

Nucleic Acids Research, 1992
We describe a chromosome translocation in a karyotype mutant of the rodent malarial parasite Plasmodium berghei. In this mutant (named EP) a small chromosome (chromosome 7), which has exhibited a size range between 0.9 and 1.4 Mb in other clones of P. berghei, is translocated to chromosome 13 or 14 with a size of about 3 Mb.
C J, Janse, J, Ramesar, B, Mons
openaire   +3 more sources

Single‐Cell Transcriptomics and Development of Gametocyte‐Specific Molecular Markers for Avian Malaria Parasites

Molecular Ecology Resources, Volume 26, Issue 5, July 2026.
ABSTRACT Avian malaria, caused by Plasmodium parasites, poses a significant threat to bird populations worldwide, particularly in vulnerable island ecosystems. Yet, progress in understanding avian malaria transmission dynamics has been hampered by the lack of molecular tools to quantify and sex the transmissible stages of the parasite: the male and ...
A. Berthomieu, I. Rizos, J. W. Bagnoli, S. Gandon, A. M. Talman, A. Rivero   +5 more
wiley   +1 more source

HaloPROTAC3 does not trigger the degradation of the halotagged parasitophorous vacuole membrane protein UIS4 during Plasmodium liver stage development

Scientific Reports
Targeted protein degradation (TPD) is a novel strategy for developing therapeutics against pathogens. Prior to causing malaria, Plasmodium parasites replicate within hepatocytes as liver stages, surrounded by a parasitophorous vacuole membrane (PVM).
Melanie Lam, Alexandra Probst, Laura Torres, Ashley A. Lantigua, Matthew E. Fishbaugher, Jyothsna R. Kumar, Manuel Saldivia, Allison Torres, Shreeya Hegde, Maya Aleshnick, Charlie Jennison, Sarah G. H. Roberson, Chester J. Joyner, Ashley M. Vaughan, Brandon K. Wilder, Carole Manneville, Erika L. Flannery, David Marcellin, Beat Nyfeler, Zacharias Thiel, Sebastian A. Mikolajczak, Anke Harupa, Gabriel Mitchell   +22 more
doaj   +1 more source

Erythroferrone contributes to hepcidin repression in a mouse model of malarial anemia

Haematologica, 2017
Malaria, a major global health challenge worldwide, is accompanied by a severe anemia secondary to hemolysis and increased erythrophagocytosis. Iron is an essential functional component of erythrocyte hemoglobin and its availability is controlled by the ...
Chloé Latour, Myriam F. Wlodarczyk, Grace Jung, Aurélie Gineste, Nicolas Blanchard, Tomas Ganz, Marie-Paule Roth, Hélène Coppin, Léon Kautz   +8 more
doaj   +1 more source