Results 41 to 50 of about 18,594 (231)

Generation of transgenic rodent malaria parasites by transfection of cell culture-derived merozoites

Malaria Journal, 2017
Background Malaria research is greatly dependent on and has drastically advanced with the possibility of genetically modifying Plasmodium parasites. The commonly used transfection protocol by Janse and colleagues utilizes blood stage-derived Plasmodium ...
Gesine Kaiser, Mariana De Niz, Paul-Christian Burda, Livia Niklaus, Rebecca Limenitakis Stanway, Volker Heussler   +5 more
doaj   +1 more source

Phosphoinositide metabolism links cGMP-dependent protein kinase G to essential Ca²⁺ signals at key decision points in the life cycle of malaria parasites [PDF]

, 2014
This work was funded by grants from the Wellcome Trust (WT098051 and 079643/Z/06/Z) and the Medical Research Council (G0501670) to OB, a Wellcome Trust project grant to DB (WT094752), a Wellcome Trust Grant (WT093228) to TKS, a Marie Curie Fellowship ...
Katrin Volkmann, Chappell, Lia, Brochet, M., Oliver Billker, Eloise Thompson, Billker, Oliver,, Mathieu Brochet, Berriman, Matthew, Jyoti Choudhary (261900), Frank Schwach, Rayner, Julian C., Rayner, Julian C, Jyoti Choudhary, Lia Chappell (530631), Sebastian, Sarah, Lia Chappell, Chappell, L., Terry K. Smith (112550), Gomes, Ana Rita, Frank Schwach (530630), Ana Rita Gomes, Oliver Billker (92636), Smith, T.K., Thompson, E., Schwach, F., Sebastian, S., Baker, David A, Volkmann, K., Sarah Sebastian (530629), Volkmann, Katrin, David A Baker, Terry K Smith, Ana Rita Gomes (220735), Collins, Mark O., Smith, Terry K., Mark O Collins, Gomes, A.R., Collins, M.O., David A. Baker (122252), Choudhary, J., Julian C Rayner, Brochet, Mathieu, Mathieu Brochet (149272), Billker, Oliver, Collins, Mark O, Mark O. Collins (131229), Billker, O., Schwach, Frank, Berriman, M., Sarah Sebastian, Rayner, J.C., Matthew Berriman (5353), Baker, David A., Thompson, Eloise, Smith, Terry K, Matthew Berriman, Choudhary, Jyoti, Eloise Thompson (376344), Baker, D.A., Julian C. Rayner (121198), Katrin Volkmann (149256)   +60 more
core   +1 more source

Behaviour of Plasmodium berghei in some Rodents [PDF]

Nature, 1950
Plasmodium berghei Vincke and Lips 1948 is the first plasmodium found infective for rats and mice1. Vincke and Lips isolated this parasite from a wild tree-rat Thamnonys and found that it produced a fatal infection in mice and rats.
S, ADLER, M, YOELI, A, ZUCKERMAN
openaire   +2 more sources

Plasmodium berghei-infection induces volume-regulated anion channel-like activity in human hepatoma cells

, 2009
Parasite infection can lead to alterations in the permeability of host plasma membranes. Presented here is the first demonstration that this phenomenon occurs in Plasmodium‐infected liver cells.
Staines, Henry M., Marques, Catarina A., Krishna, Sanjeev, Mota, Maria M., Derbyshire, Elvira T., Marques, CA, Prudêncio, M, Mota, MM, Staines, HM, Prudêncio, Miguel, Krishna, S, Derbyshire, ET   +11 more
core   +1 more source

Malaria ookinetes exhibit multiple markers for apoptosis-like programmed cell death in vitro. [PDF]

, 2009
Background: A wide range of unicellular eukaryotes have now been shown to undergo a form of programmed cell death (PCD) that resembles apoptosis; exhibiting morphological and, in some cases, biochemical markers typical of metazoans. However, reports that
Arambage, S.C., Karen M Grant, Grant, Karen M., Pardo, Ian, Hilary Hurd, Grant, K.M., Hurd, Hilary, Ranford-Cartwright, Lisa, Ian Pardo, Lisa Ranford-Cartwright, Hurd, H., Pardo, I., Shashini C Arambage, Arambage, Shashini C., Ranford-Cartwright, L.C.   +14 more
core   +1 more source

Prophylactic effects of Kaempferia Galanga against Plasmodium berghei: in vivo study

Jurnal Teknologi Laboratorium, 2022
Recently, medicinal plants have been the main source in treating malaria. Kaempferia galanga was investigated as an antioxidant, and anti-inflammation. In vivo study of K. galanga had been verified as antimalarial for severe malaria.
Novyan Lusiyana
doaj   +1 more source

Fractions 14 and 36K of Metabolite Extract Streptomyces hygroscopicus subsp. Hygroscopicus Have Antimalarial Activities Against Plasmodium berghei in vitro

Infection and Drug Resistance, 2023
Loeki Enggar Fitri,1,2,* Agustina Tri Endharti,1 Hafshah Yasmina Abidah,3,4,* Alif Raudhah Husnul Khotimah,3,4,* Heni Endrawati1 1Department of Parasitology, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia; 2Malaria Research ...
Fitri LE, Endharti AT, Abidah HY, Khotimah ARH, Endrawati H   +4 more
doaj  

KEMAMPUAN MALARISIDAL NANOPARTIKEL EKSTRAK DAUN JUWET (Syzygium cumini) SEBAGAI TERAPI AJUVAN PADA HISTOPATOLOGI HATI MENCIT (Mus musculus) PENDERITA MALARIA

Journal of Basic Medical Veterinary, 2020
The aimed of this study is to know malaricidal ability of nanoparticle juwet (Syzygium cumini) leaf extract as adjuvant therapy on liver histopathological of mice (Mus musculus) which infected by Plasmodium berghei.
Mahendra Pujiyanto, Lilik Maslachah, Nusdianto Triakoso, Mochamad Lazuardi, Chairul Anwar, Djoko Legowo   +5 more
doaj   +1 more source

Proteomic analysis of the Plasmodium male gamete reveals the key role for glycolysis in flagellar motility. [PDF]

, 2014
BACKGROUND: Gametogenesis and fertilization play crucial roles in malaria transmission. While male gametes are thought to be amongst the simplest eukaryotic cells and are proven targets of transmission blocking immunity, little is known about their ...
Mara Lawniczak, Wass, Mark N., Arthur M Talman, Sinden, Robert E., Prieto, Judith H, Yates, JR, Talman, Arthur M, Sinden, Robert, Michael JE Sternberg, Sinden, Robert E, Stanway, RS, Graham, David R, Marques, S, Ubaida-Mohien, Ceereena, Tao Xu, Marques, Sara, Ecker, A, Sternberg, MJ, Sternberg, Michael J E, Yates, John R., III, Prieto, JH, Talman, AM, Rhoel R Dinglasan, Xu, T, Ubaida-Mohien, C, Sanjeev Krishna, Lawniczak, Mara, Wass, MN, Wass, Mark N, Dinglasan, Rhoel R, Robert E Sinden, Talman, Arthur M., Christophides, Georges K., Christophides, Georges K, Andrea Ecker, Sara Marques, Ceereena Ubaida-Mohien, Sternberg, Michael JE, Limenitakis Stanway, Rebecca, Dinglasan, Rhoel R., Georges K Christophides, Sternberg, MJE, Yates, John R, Roland Frank, Stanway, Rebecca S., Graham, David R., Xu, Tao, Frank, Roland, Prieto, Judith H., Rebecca S Stanway, Dinglasan, RR, John R Yates, Sternberg, Michael J. E., Stanway, Rebecca S, Graham, DR, Krishna, S, Mark N Wass, Christophides, GK, Lawniczak, M, Sinden, RE, Frank, R, Krishna, Sanjeev, Ecker, Andrea, David R Graham, Judith H Prieto   +64 more
core   +1 more source

Plasmodium berghei circumvents immune responses induced by merozoite surface protein 1- and apical membrane antigen 1-based vaccines. [PDF]

PLoS ONE, 2010
BACKGROUND: Two current leading malaria blood-stage vaccine candidate antigens for Plasmodium falciparum, the C-terminal region of merozoite surface protein 1 (MSP1(19)) and apical membrane antigen 1 (AMA1), have been prioritized because of outstanding ...
Shigeto Yoshida, Hiroshi Nagumo, Takashi Yokomine, Hitomi Araki, Ayaka Suzuki, Hiroyuki Matsuoka   +5 more
doaj   +1 more source