Results 31 to 40 of about 18,594 (231)

Suppression of experimental cerebral malaria by disruption of malate:quinone oxidoreductase

Malaria Journal, 2017
Background Aspartate, which is converted from oxaloacetate (OAA) by aspartate aminotransferase, is considered an important precursor for purine salvage and pyrimidine de novo biosynthesis, and is thus indispensable for the growth of Plasmodium parasites ...
Mamoru Niikura, Keisuke Komatsuya, Shin-Ichi Inoue, Risa Matsuda, Hiroko Asahi, Daniel Ken Inaoka, Kiyoshi Kita, Fumie Kobayashi   +7 more
doaj   +1 more source

A member of the tryptophan-rich protein family is required for efficient sequestration of Plasmodium berghei schizonts.

PLoS Pathogens, 2022
Protein export and host membrane remodeling are crucial for multiple Plasmodium species to establish a niche in infected hosts. To better understand the contribution of these processes to successful parasite infection in vivo, we sought to find and ...
Julie-Anne Gabelich, Josephine Grützke, Florian Kirscht, Oliver Popp, Joachim M Matz, Gunnar Dittmar, Melanie Rug, Alyssa Ingmundson   +7 more
doaj   +1 more source

Uji Aktivitas Antimalaria dari Spons Xestospongia sp. Asal Pulau Yapen secara In Vivo

Jurnal Kelautan Tropis, 2021
It is generally admitted that marine sponge has rich of secondary metabolite as alkaloids, peptides and terpene. Those various compounds can be used for antimalarial drug.  This study aims to evaluate the in vivo antimalarial activity and to characterize
Murtihapsari Murtihapsari, Mathelda K. Roreng, Apriani Parubak, Alif Rahman   +3 more
doaj   +1 more source

Genome wide analysis of inbred mouse lines identifies a locus containing Ppar-γ as contributing to enhanced malaria surviva [PDF]

, 2010
The genetic background of a patient determines in part if a person develops a mild form of malaria and recovers, or develops a severe form and dies. We have used a mouse model to detect genes involved in the resistance or susceptibility to Plasmodium ...
Winzeler, E.A., Wiltshire, T., Selina E R Bopp, Waters Andrew P., Andrew P. Waters, Luzader, A., Bopp, S.E.R., Waters, A.P., Steffy Brian M., Henson Kerstin, Winzeler Elizabeth A., Ramachandran, V., Suzuki Oscar, Lindstrom, M., Merle Lindstrom, Lindstrom Merle, Oscar Suzuki, Henson, K., Tim Wiltshire, Suzuki, O., Yingyao Zhou, Janse, C., Selina E. R. Bopp, Elizabeth A Winzeler, Spooner, M., Bopp Selina E. R., Zhou Yingyao, Brian M. Steffy, Kerstin Henson, Zhou, Y.Y., Chris Janse, Steffy, B.M., Janse Chris, Wiltshire Tim, Vandana Ramachandran, Muriel Spooner, Luzader Angelina, Angelina Luzader, Ramachandran Vandana, Spooner Muriel, Elizabeth A. Winzeler, Zhou, Y., Brian M Steffy, Andrew P Waters   +43 more
core   +1 more source

Three Members of the 6-cys Protein Family of Plasmodium Play a Role in Gamete Fertility [PDF]

, 2010
The process of fertilization is critically dependent on the mutual recognition of gametes and in Plasmodium, the male gamete surface protein P48/45 is vital to this process.
Hans, Kroeze, Andrew P., Waters, Hendrik G., Stunnenberg, Ben C. L, van Schaijk, Jai, Ramesar, Wijnand M., Eling, Robert W., Sauerwein, Maaike W., van Dooren, Melissa, von Dijk, Geert-Jan, van Gemert, Shahid SM, Khan, Janse, Chris J., Kaczanowski, Szymon   +12 more
core   +3 more sources

Extract of Morinda lucida leaf rescues hypoglycaemic and dyslipidaemic conditions in Plasmodium berghei-infected mice [PDF]

Bulletin of Natural Sciences Research, 2022
Increasing drug resistance is a great threat to malaria control. Therefore, a continuous investigation into alternative therapy to mitigate malaria-associated damages is important.
Abdulkareem Adam Olaitan, Babamale Abdulkareem Olarewaju, Anifowoshe Abass Toba, Opeyemi Olufunke Adenike Opeyemi Olufunke Adenike, Oloriegbe Nusirat, Adamolekun Comfort, Adetula Samson, Ala Adeola Adefoluke   +7 more
doaj   +1 more source

Transition of plasmodium sporozoites into liver stage-like forms is regulated by the RNA binding protein pumilio [PDF]

, 2011
Many eukaryotic developmental and cell fate decisions that are effected post-transcriptionally involve RNA binding proteins as regulators of translation of key mRNAs.
Gunnar R Mair, Waters, Andrew, Waters, A.P., Prudêncio, M., Joanna Braks, Braks, Joanna, Mair Gunnar R., Braks, J., Theresa Feltwell, Prudêncio, Miguel, Mair, Gunnar R., Gomes-Santos, Carina S. S., Feltwell Theresa, Pain, A., Janse, C., Mota, Maria M., Mota, M.M., Céline Carret, Carret, Céline, Shahid Khan, Gomes, Ana Rita, Khan, S., Miguel Prudêncio, Ana Rita Gomes, Carina S S Gomes-Santos, Mota Maria M., Khan Shahid, Carina S. S. Gomes-Santos, Prudêncio Miguel, Maria M. Mota, Waters Andrew, Gomes-Santos Carina S. S., Gomes-Santos, C.S.S., Gomes, A.R., Mair, G.R., Andrew Waters, Gunnar R. Mair, Gomes Ana Rita, Feltwell, T., Carret Céline, Pain, Arnab, Khan, Shahid, Janse, Chris, Chris Janse, Maria M Mota, Carret, C., Janse Chris, Waters, A., Arnab Pain, Pain Arnab, Feltwell, Theresa, Braks Joanna   +51 more
core   +1 more source

Rapid and Specific Action of Methylene Blue against Plasmodium Transmission Stages

Pharmaceutics, 2022
Methylene blue (MB) is the oldest synthetic anti-infective. Its high potency against asexual and sexual stages of malaria parasites is well documented.
Nathanaël Saison, Jean-François Franetich, Yudi T. Pinilla, Anton Hoffmann, Stravensky T. Boussougou-Sambe, Barclaye Ngossanga, Maurel Tefit, Kutub Ashraf, Nadia Amanzougaghene, Shahin Tajeri, Ayola A. Adegnika, Dominique Mazier, Steffen Borrmann   +12 more
doaj   +1 more source

Sex ratios in the rodent malaria parasite, Plasmodium chabaudi [PDF]

, 2003
The sex ratios of malaria and related Apicomplexan parasites play a major role in transmission success. Here, we address 2 fundamental issues in the sex ratios of the rodent malaria parasite, Plasmodium chabaudi.
West, SA, West, S A, Read, A F, REECE, S. E., West, S. A., Read, A. F., Duncan, A B, West, Stuart A, Reece, S E, Duncan, A., Reece, SE, Duncan, AB, Read, AF, Duncan, Alison B, Read, Andrew F   +14 more
core   +1 more source

Proteomic profiling of Plasmodium sporozoite maturation identifies new proteins essential for parasite development and infectivity [PDF]

, 2008
<i>Plasmodium falciparum</i> sporozoites that develop and mature inside an <i>Anopheles</i> mosquito initiate a malaria infection in humans.
Lasonder Edwin, Edwin Lasonder, Khan, Shahid M., Geert-Jan van Gemert, Mair, G. R., Gunnar R Mair, Stunnenberg Hendrik G., Waters, A.P., Mann, Matthias, van Gemert, G. J., Vermunt Adriaan M. W., Mair Gunnar R., Huynen, Martijn A., Shahid M Khan, Kroeze Hans, Stunnenberg, Hendrik G, Mair, Gunnar R., van Gemert, Geert-Jan, Janse, C., van Gemert Geert-Jan, Sauerwein, R., Stunnenberg, H. G., Janse, C.J., Mann, M., Kroeze, H., Vermunt, Adriaan M. W., Bruno G Douradinha, Luty, A., Vermunt, A.M.W., Khan, S. M., Khan, S., Vermunt, Adriaan M W, Khan, Shahid M, Chris J Janse, Sauerwein Robert W., van Gemert, G.J., Douradinha, Bruno G., Hans Kroeze, Adriaan M W Vermunt, Sauerwein, R. W., Robert W Sauerwein, Sauerwein, Robert W., Adrian J F Luty, Andrew P Waters, Kroeze, Hans, Sauerwein, Robert W, Douradinha, B.G., Luty, Adrian J F, Mann Matthias, Waters Andrew P., Lasonder, Edwin, van Noort, V., Luty, A.J.F., Sauerwein, R.W., Luty, A. J., Huynen Martijn A., Gemert, G.J.A. van, Douradinha, B. G., Mair, G.R., Douradinha, B., Khan, S.M., van Noort Vera, Huynen, Martijn A, Noort, V. van, Vera van Noort, Mair, Gunnar R, Janse, Chris J., Khan Shahid M., Stunnenberg, H., van Noort, Vera, Hendrik G Stunnenberg, Douradinha Bruno G., Lasonder, E., Janse, Chris J, Mair, G., Huynen, M., Matthias Mann, Vermunt, A. M., Waters, A. P., Janse, C. J., Waters, Andrew P, Luty Adrian J. F., van Gemert, G., Waters, A., Waters, Andrew P., Stunnenberg, H.G., Douradinha, Bruno G, Janse Chris J., Stunnenberg, Hendrik G., Luty, Adrian J. F., Huynen, M.A., Martijn A Huynen, Vermunt, A., Huynen, M. A.   +93 more
core   +1 more source