Results 11 to 20 of about 18,594 (231)

Erythrocyte Membrane Protein 3 (EMAP3) Is Exposed on the Surface of the Plasmodium berghei Infected Red Blood Cell. [PDF]

Mol Microbiol
Erythrocyte membrane protein 3 (EMAP3) is a novel Plasmodium berghei protein that is trafficked to the outer membrane surface of the infected red blood cell (iRBC). EMAP3 is not critical for parasite growth or sequestration but offers a new scaffold for displaying Plasmodium falciparum proteins on iRBCs.
Hernandez SRC, Rashpa R, Jonsdottir TK, Paoletta MS, Ter Beek J, Díaz MR, Krol JMM, Chevalley-Maurel S, Ishizaki T, Berntsson RP, Janse CJ, Franke-Fayard B, Brochet M, Bushell ESC.   +13 more
europepmc   +2 more sources

Anopheles gambiae immune responses to human and rodent Plasmodium parasite species. [PDF]

PLoS Pathogens, 2006
Transmission of malaria is dependent on the successful completion of the Plasmodium lifecycle in the Anopheles vector. Major obstacles are encountered in the midgut tissue, where most parasites are killed by the mosquito's immune system.
Yuemei Dong, Ruth Aguilar, Zhiyong Xi, Emma Warr, Emmanuel Mongin, George Dimopoulos   +5 more
doaj   +1 more source

Reproductive indices in malaria infested mice treated with antimalarials, Phyllanthus amarus combined with vitamins

Bulletin of Faculty of Pharmacy Cairo University, 2018
Malaria disease is caused by the plasmodium organism transmitted into humans by the female anopheles mosquito. The effect of chloroquine, artesunate or Phyllantus amarus alone or combined with vitamins A, B, C or K on male fertility indices has received ...
Matthew Obaineh Ojezele, Ighodaro Igbe, Agbonlahor Okhuarobo   +2 more
doaj   +1 more source

Salivary gland-specific P. berghei reporter lines enable rapid evaluation of tissue-specific sporozoite loads in mosquitoes [PDF]

, 2012
Malaria is a life-threatening human infectious disease transmitted by mosquitoes. Levels of the salivary gland sporozoites (sgs), the only mosquito stage infectious to a mammalian host, represent an important cumulative index of <i>Plasmodium</i&
Levashina Elena A., Soichot, J., Blandine M Franke-Fayard, Annika Rademacher, Waters Andrew P., Chris J. Janse (12383), Elena A Levashina, Waters, A.P., Jai Ramesar (49002), Chandra Ramakrishnan, Ramakrishnan, C., Andrew P. Waters (15293), Soichot Julien, Costa, G., Costa Giulia, Ramakrishnan Chandra, Levashina, E.A., Giulia Costa (166412), Julien Soichot, Rademacher, A., Janse, C.J., Franke-Fayard Blandine M., Ramesar, J., Annika Rademacher (166404), Elena A. Levashina (160880), Franke-Fayard, B.M., Janse Chris J., Chris J Janse, Jai Ramesar, Rademacher Annika, Ramesar Jai, Blandine M. Franke-Fayard (166421), Giulia Costa, Julien Soichot (166407), Andrew P Waters, Chandra Ramakrishnan (134246)   +35 more
core   +1 more source

Using green fluorescent malaria parasites to screen for permissive vector mosquitoes

Malaria Journal, 2006
Background The Plasmodium species that infect rodents, particularly Plasmodium berghei and Plasmodium yoelii, are useful to investigate host-parasite interactions. The mosquito species that act as vectors of human plasmodia in South East Asia, Africa and
Martin Beatrice, Frischknecht Friedrich, Thiery Isabelle, Bourgouin Catherine, Menard Robert   +4 more
doaj   +1 more source

Ecology of asynchronous asexual replication: the intraerythrocytic development cycle of Plasmodium berghei is resistant to host rhythms

Malaria Journal, 2021
Background Daily periodicity in the diverse activities of parasites occurs across a broad taxonomic range. The rhythms exhibited by parasites are thought to be adaptations that allow parasites to cope with, or exploit, the consequences of host activities
Aidan J. O’Donnell, Sarah E. Reece
doaj   +1 more source

Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection. [PDF]

, 2011
IFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection ...
Couper, Kevin N, de, Souza JB, Riley, Eleanor M, Hafalla, Julius CR, Murungi, Linda, Greig, R, Julius C. R. Hafalla, de Souza, J Brian, Hafalla, Julius C R, Linda Murungi, Villegas-Mendez, Ana, Villegas-Mendez, A, Rachel Greig, Greig, Rachel, J. Brian de Souza, Shaw, TN, Tovah N. Shaw, De Souza, J. Brian, Kevin N. Couper, Shaw, Tovah N, Eleanor M. Riley, Riley, Eleanor M., Hafalla, JC, Ana Villegas-Mendez, Shaw, Tovah N., Couper, KN., Couper, Kevin N., Riley, EM, Murungi, L   +28 more
core   +1 more source

Amodiaquine resistance in Plasmodium berghei is associated with PbCRT His95Pro mutation, loss of chloroquine, artemisinin and primaquine sensitivity, and high transcript levels of key transporters [version 2; referees: 2 approved, 1 approved with reservations]

Wellcome Open Research, 2018
Background: The human malaria parasite Plasmodium falciparum has evolved drug evasion mechanisms to all available antimalarials. The combination of amodiaquine-artesunate is among the drug of choice for treatment of uncomplicated malaria.
Loise Ndung'u, Benard Langat, Esther Magiri, Joseph Ng'ang'a, Beatrice Irungu, Alexis Nzila, Daniel Kiboi   +6 more
doaj   +1 more source

The glutathione biosynthetic pathway of Plasmodium is essential for mosquito transmission [PDF]

, 2009
1Infection of red blood cells (RBC) subjects the malaria parasite to oxidative stress. Therefore, efficient antioxidant and redox systems are required to prevent damage by reactive oxygen species. Plasmodium spp.
Vega-Rodríguez Joel, Franke-Fayard Blandine, Coppens Isabelle, Waters Andrew P., Dinglasan, R.R., Andrew P. Waters, Joel Vega-Rodríguez, Rhoel R. Dinglasan, Jacobs-Lorena Marcelo, José F Rodríguez-Orengo, Jacobs-Lorena, M., Rodríguez-Orengo José F., Blandine Franke-Fayard, Chris J. Janse, Vega-Rodriguez, J., Isabelle Coppens, José F. Rodríguez-Orengo, Serrano Adelfa E., Adelfa E. Serrano, Janse, C.J., Serrano, A.E., Rhoel R Dinglasan, Prakash Srinivasan, Waters, A., Adelfa E Serrano, Marcelo Jacobs-Lorena, Pastrana-Mena Rebecca, Janse Chris J., Chris J Janse, Dinglasan Rhoel R., Rodriguez-Orengo, J.F., Srinivasan, P., Pastrana-Mena, R., Rebecca Pastrana-Mena, Franke-Fayard, B., Andrew P Waters   +35 more
core   +1 more source

Continuous exposure to Plasmodium results in decreased susceptibility and transcriptomic divergence of the Anopheles gambiae immune system

BMC Genomics, 2007
Background Plasmodium infection has been shown to compromise the fitness of the mosquito vector, reducing its fecundity and longevity. However, from an evolutionary perspective, the impact of Plasmodium infection as a selective pressure on the mosquito ...
Dimopoulos George, Dong Yuemei, Das Suchismita, Aguilar Ruth   +3 more
doaj   +1 more source