Results 11 to 20 of about 90,646 (224)

Malaria ookinetes exhibit multiple markers for apoptosis-like programmed cell death in vitro. [PDF]

, 2009
Background: A wide range of unicellular eukaryotes have now been shown to undergo a form of programmed cell death (PCD) that resembles apoptosis; exhibiting morphological and, in some cases, biochemical markers typical of metazoans. However, reports that
Arambage, S.C., Karen M Grant, Grant, Karen M., Pardo, Ian, Hilary Hurd, Grant, K.M., Hurd, Hilary, Ranford-Cartwright, Lisa, Ian Pardo, Lisa Ranford-Cartwright, Hurd, H., Pardo, I., Shashini C Arambage, Arambage, Shashini C., Ranford-Cartwright, L.C., Arambage Shashini C, Ranford-Cartwright Lisa, Pardo Ian, Grant Karen M, Hurd Hilary   +19 more
core   +5 more sources

Reproductive indices in malaria infested mice treated with antimalarials, Phyllanthus amarus combined with vitamins

Bulletin of Faculty of Pharmacy Cairo University, 2018
Malaria disease is caused by the plasmodium organism transmitted into humans by the female anopheles mosquito. The effect of chloroquine, artesunate or Phyllantus amarus alone or combined with vitamins A, B, C or K on male fertility indices has received ...
Matthew Obaineh Ojezele, Ighodaro Igbe, Agbonlahor Okhuarobo   +2 more
doaj   +1 more source

Salivary gland-specific P. berghei reporter lines enable rapid evaluation of tissue-specific sporozoite loads in mosquitoes [PDF]

, 2012
Malaria is a life-threatening human infectious disease transmitted by mosquitoes. Levels of the salivary gland sporozoites (sgs), the only mosquito stage infectious to a mammalian host, represent an important cumulative index of <i>Plasmodium</i&
Levashina Elena A., Soichot, J., Blandine M Franke-Fayard, Annika Rademacher, Waters Andrew P., Chris J. Janse (12383), Elena A Levashina, Waters, A.P., Jai Ramesar (49002), Chandra Ramakrishnan, Ramakrishnan, C., Andrew P. Waters (15293), Soichot Julien, Costa, G., Costa Giulia, Ramakrishnan Chandra, Levashina, E.A., Giulia Costa (166412), Julien Soichot, Rademacher, A., Janse, C.J., Franke-Fayard Blandine M., Ramesar, J., Annika Rademacher (166404), Elena A. Levashina (160880), Franke-Fayard, B.M., Janse Chris J., Chris J Janse, Jai Ramesar, Rademacher Annika, Ramesar Jai, Blandine M. Franke-Fayard (166421), Giulia Costa, Julien Soichot (166407), Andrew P Waters, Chandra Ramakrishnan (134246)   +35 more
core   +2 more sources

Using green fluorescent malaria parasites to screen for permissive vector mosquitoes

Malaria Journal, 2006
Background The Plasmodium species that infect rodents, particularly Plasmodium berghei and Plasmodium yoelii, are useful to investigate host-parasite interactions. The mosquito species that act as vectors of human plasmodia in South East Asia, Africa and
Martin Beatrice, Frischknecht Friedrich, Thiery Isabelle, Bourgouin Catherine, Menard Robert   +4 more
doaj   +1 more source

Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection. [PDF]

, 2011
IFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection ...
Couper, Kevin N, de, Souza JB, Riley, Eleanor M, Hafalla, Julius CR, Murungi, Linda, Greig, R, Julius C. R. Hafalla, de Souza, J Brian, Hafalla, Julius C R, Linda Murungi, Villegas-Mendez, Ana, Villegas-Mendez, A, Rachel Greig, Greig, Rachel, J. Brian de Souza, Shaw, TN, Tovah N. Shaw, De Souza, J. Brian, Kevin N. Couper, Shaw, Tovah N, Eleanor M. Riley, Riley, Eleanor M., Hafalla, JC, Ana Villegas-Mendez, Shaw, Tovah N., Couper, KN., Couper, Kevin N., Riley, EM, Murungi, L   +28 more
core   +1 more source

Plasmodium berghei-infection induces volume-regulated anion channel-like activity in human hepatoma cells [PDF]

, 2009
Parasite infection can lead to alterations in the permeability of host plasma membranes. Presented here is the first demonstration that this phenomenon occurs in Plasmodium‐infected liver cells.
Staines, Henry M., Marques, Catarina A., Krishna, Sanjeev, Mota, Maria M., Derbyshire, Elvira T., Marques, CA, Prudêncio, M, Mota, MM, Staines, HM, Prudêncio, Miguel, Krishna, S, Derbyshire, ET   +11 more
core   +1 more source

Amodiaquine resistance in Plasmodium berghei is associated with PbCRT His95Pro mutation, loss of chloroquine, artemisinin and primaquine sensitivity, and high transcript levels of key transporters [version 2; referees: 2 approved, 1 approved with reservations]

Wellcome Open Research, 2018
Background: The human malaria parasite Plasmodium falciparum has evolved drug evasion mechanisms to all available antimalarials. The combination of amodiaquine-artesunate is among the drug of choice for treatment of uncomplicated malaria.
Loise Ndung'u, Benard Langat, Esther Magiri, Joseph Ng'ang'a, Beatrice Irungu, Alexis Nzila, Daniel Kiboi   +6 more
doaj   +1 more source

Ecology of asynchronous asexual replication: the intraerythrocytic development cycle of Plasmodium berghei is resistant to host rhythms

Malaria Journal, 2021
Background Daily periodicity in the diverse activities of parasites occurs across a broad taxonomic range. The rhythms exhibited by parasites are thought to be adaptations that allow parasites to cope with, or exploit, the consequences of host activities
Aidan J. O’Donnell, Sarah E. Reece
doaj   +1 more source

The glutathione biosynthetic pathway of Plasmodium is essential for mosquito transmission [PDF]

, 2009
1Infection of red blood cells (RBC) subjects the malaria parasite to oxidative stress. Therefore, efficient antioxidant and redox systems are required to prevent damage by reactive oxygen species. Plasmodium spp.
Vega-Rodríguez Joel, Franke-Fayard Blandine, Coppens Isabelle, Waters Andrew P., Dinglasan, R.R., Andrew P. Waters, Joel Vega-Rodríguez, Rhoel R. Dinglasan, Jacobs-Lorena Marcelo, José F Rodríguez-Orengo, Jacobs-Lorena, M., Rodríguez-Orengo José F., Blandine Franke-Fayard, Chris J. Janse, Vega-Rodriguez, J., Isabelle Coppens, José F. Rodríguez-Orengo, Serrano Adelfa E., Adelfa E. Serrano, Janse, C.J., Serrano, A.E., Rhoel R Dinglasan, Prakash Srinivasan, Waters, A., Adelfa E Serrano, Marcelo Jacobs-Lorena, Pastrana-Mena Rebecca, Janse Chris J., Chris J Janse, Dinglasan Rhoel R., Rodriguez-Orengo, J.F., Srinivasan, P., Pastrana-Mena, R., Rebecca Pastrana-Mena, Franke-Fayard, B., Andrew P Waters   +35 more
core   +2 more sources

Continuous exposure to Plasmodium results in decreased susceptibility and transcriptomic divergence of the Anopheles gambiae immune system

BMC Genomics, 2007
Background Plasmodium infection has been shown to compromise the fitness of the mosquito vector, reducing its fecundity and longevity. However, from an evolutionary perspective, the impact of Plasmodium infection as a selective pressure on the mosquito ...
Dimopoulos George, Dong Yuemei, Das Suchismita, Aguilar Ruth   +3 more
doaj   +1 more source