Results 71 to 80 of about 12,801 (184)

In vitro activity and in vivo efficacy of omadacycline against Plasmodium species

Malaria Journal
Background Doxycycline is currently the only tetracycline-class antibiotic recommended for malaria prophylaxis. Omadacycline, a semisynthetic aminomethylcycline approved for treatment of adults with community-acquired bacterial pneumonia and acute ...
Michael S. Madejczyk, Susan E. Leed, Karl Kudyba, Alison Roth, Monica L. Martin, Patricia Lee, Diane Anastasiou, Jessica V. Pierce, Alisa W. Serio, Diana Caridha   +9 more
doaj   +1 more source

Neuroprotective and antimalarial effects of Juglans regia leaf extracts in a murine model of cerebral malaria

Frontiers in Veterinary Science
BackgroundMalaria is a major public health problem caused by the apicomplexan Plasmodium parasite. Cerebral malaria (CM) is the most critical outcome of Plasmodium infection.
Afra Alharbi, Shurug Albasyouni, Esam Al-Shaebi, Saleh Al Quraishy, Rewaida Abdel-Gaber   +4 more
doaj   +1 more source

Multi-system dysregulation in placental malaria contributes to adverse perinatal outcomes in mice

Infection and Immunity
Sequestration of Plasmodium parasites in the placental vasculature contributes to increased morbidity and mortality in pregnant compared to non-pregnant patients in malaria-endemic regions.
Phebe Ekregbesi, Brittany Seibert, Maclaine A. Parish, Yevel Flores-Garcia, Patrick S. Creisher, Joseph P. Hoffmann, Jennifer A. Liu, Cory Brayton, Fidel Zavala, Sabra L. Klein   +9 more
doaj   +1 more source

Taurine potentiates artemisinin efficacy against malaria by modulating the immune response in Plasmodium berghei-infected mice

Parasites & Vectors
Background Artemisinin (ART) is a frontline drug for the treatment of malaria; however, the emergence of ART-resistant Plasmodium strains necessitates increasing ART sensitivity.
Xin Li, Ning Jiang, Qilong Li, Kexin Zheng, Yiwei Zhang, Xiaoyu Sang, Ying Feng, Ran Chen, Qijun Chen   +8 more
doaj   +1 more source

Plasmodium berghei High-Throughput (PbHiT): a CRISPR-Cas9 System to Study Genes at Scale. [PDF]

Bio Protoc
Jonsdottir TK, Paoletta MS, Henriksson J, Bushell ESC.   +3 more
europepmc   +1 more source

Identification of serine/arginine-rich splicing factor 1-interacting proteins in Plasmodium berghei. [PDF]

Malar J
Niikura M, Koyama Y, Fukuda Y, Kato K, Fukutomi T.   +4 more
europepmc   +1 more source

<i>Plasmodium berghei</i> serine repeat antigen 3 (PbSERA3) is required for hepatic merozoite egress. [PDF]

mBio
Singh D, Patri S, Veeda N, Verma CK, Kavati A, Segireddy RR, Kolli SK, Arun Kumar K.   +7 more
europepmc   +1 more source

Antimalarial Potency of <i>Tinospora crispa</i> Stem Extract and Artesunate Against <i>Plasmodium berghei</i>: A Study on Combination Therapy. [PDF]

J Trop Med
Ounjaijean S, Somsak V.
europepmc   +1 more source

Humanization of Drug Metabolism in the <i>Plasmodium berghei</i> Mouse Model for Antimalarial Drug Discovery. [PDF]

ACS Infect Dis
MacLeod AK, Merino C, Viera-Morilla S, Frame L, Tavendale A, Duncan C, Ferguson L, Pinto EG, Simeons FRC, Gomez-Jimenez V, García AB, Riley J, Shishikura Y, Martínez-Martínez MS, Wolf CR, Read KD.   +15 more
europepmc   +1 more source

The Plasmodium berghei merozoite protein PbGAC is critically involved in erythrocyte binding during invasion. [PDF]

Parasit Vectors
Gao J, Jiang N, Zhang Y, Chen R, Feng Y, Sang X, Chen Q.   +6 more
europepmc   +1 more source