Results 71 to 80 of about 90,646 (224)

Spatiotemporal and functional characterisation of the Plasmodium falciparum cGMP-dependent protein kinase. [PDF]

, 2012
Signalling by 3'-5'-cyclic guanosine monophosphate (cGMP) exists in virtually all eukaryotes. In the apicomplexan parasite Plasmodium, the cGMP-dependent protein kinase (PKG) has previously been reported to play a critical role in four key stages of the ...
Baker, David A, Lev Solyakov (122244), Solyakov, Lev, David A Baker, Flueck, Christian, Lev Solyakov, L. Solyakov (7638338), Hopp Christine S., Flueck Christian, Andrew Tobin (122248), David A. Baker (122252), Christine S Hopp, David A. Baker, D. A. Baker (7638335), A. B. Tobin (7638326), Solyakov Lev, C. Flueck (7638332), Andrew Tobin, Christine S. Hopp (122239), Baker David A., Tobin Andrew, Christian Flueck, C. S. Hopp (7638329), Tobin, Andrew, Christian Flueck (122240), Hopp, Christine S   +25 more
core   +1 more source

Erythroferrone contributes to hepcidin repression in a mouse model of malarial anemia

Haematologica, 2017
Malaria, a major global health challenge worldwide, is accompanied by a severe anemia secondary to hemolysis and increased erythrophagocytosis. Iron is an essential functional component of erythrocyte hemoglobin and its availability is controlled by the ...
Chloé Latour, Myriam F. Wlodarczyk, Grace Jung, Aurélie Gineste, Nicolas Blanchard, Tomas Ganz, Marie-Paule Roth, Hélène Coppin, Léon Kautz   +8 more
doaj   +1 more source

Quantitative electroencephalographic measures during postmalarial epileptogenesis

Epilepsia, Volume 67, Issue 7, Page 3602-3611, July 2026.
Abstract Objective Severe malaria with neurologic involvement contributes significantly to the global burden of acquired pediatric epilepsy. We studied quantitative electroencephalographic (EEG) measures in postmalarial epileptogenesis. Methods A total of 186 patients, aged 6 months to 11 years, with confirmed central nervous system malaria were ...
Rasesh B. Joshi, Suzanna Mwanza, Hitten P. Zaveri, Joseph Kasolo, Angela Masempela, Thelma Musakanya, Tina Mwale, Violet Nambeye, Rosemary Nyriongo, Ruth A. Tembo, Christopher Cortina, Bo Zhang, Gretchen L. Birbeck, Alexander Rotenberg, Archana A. Patel   +14 more
wiley   +1 more source

Chromosome translocation inPlasmodium berghei

Nucleic Acids Research, 1992
We describe a chromosome translocation in a karyotype mutant of the rodent malarial parasite Plasmodium berghei. In this mutant (named EP) a small chromosome (chromosome 7), which has exhibited a size range between 0.9 and 1.4 Mb in other clones of P. berghei, is translocated to chromosome 13 or 14 with a size of about 3 Mb.
C J, Janse, J, Ramesar, B, Mons
openaire   +3 more sources

Curcumin‐Loaded Nanocapsules: Population Pharmacokinetic and Time‐to Event Modeling in Healthy Rats and LPS‐Induced Inflammation Flies

Nano Select, Volume 7, Issue 7, July 2026.
ABSTRACT Curcumin (CUR) is a bioactive compound with antioxidant, anti‐inflammatory, and anticancer properties, though its clinical use is limited by low bioavailability, rapid metabolism, and poor solubility. To address these challenges, our study investigates nanoencapsulated curcumin (NC‐CUR) to enhance its pharmacokinetics and therapeutic efficacy,
Ana Pozzato Funghetto‐Ribeiro, Camila Pacheco, Flávia Teixeira, Joane Ferreira, Vitória Gallarreta, Clémence Boivin‐Champeaux, Eliana Fernandes, Gustavo Guerra, Francine Azeredo, Sandra Elisa Haas   +9 more
wiley   +1 more source

Plasmodium falciparum liver stage antigen-1 is cross-linked by tissue transglutaminase [PDF]

, 2011
Background Plasmodium falciparum sporozoites injected by mosquitoes into the blood rapidly enter liver hepatocytes and undergo pre-erythrocytic developmental schizogony forming tens of thousands of merozoites per hepatocyte.
Piacentini Mauro, Rodolfo, Carlo, Giuseppina Di Giacomo, Doerig Christian, Di Giacomo, Giuseppina, Piacentini, Mauro, Lanar David E, William S Nicoll, Di Giacomo, G, Nicoll, W.S., Doerig, C., Hollingdale, M.R., David E Lanar, Sacci, JB, Sacci, John, John B Sacci, Piacentini, M, Zoe JM Holland, Michael R Hollingdale, Rodolfo, C., Lanar, D.E., Nicoll William S, Mauro Piacentini, Sacci John B, Doerig, Christian, Lanar, DE, Sacci, J.B., Hollingdale Michael R, Rodolfo Carlo, Hollingdale, MR, Rodolfo, C, Holland, Zoe, Lanar, David, Christian Doerig, Holland Zoe JM, Holland, Z.J.M., Carlo Rodolfo, Di Giacomo Giuseppina, Holland, ZJ, Nicoll, William, Nicoll, WS, Doerig, C, Hollingdale, Michael   +42 more
core   +1 more source

VAMP3 vesicles support host protein recruitment and Plasmodium liver stage development

mBio
Plasmodium remodels the host liver cell as an obligatory step in malaria infection. Although several host proteins are recruited to the parasitophorous vacuole membrane (PVM) after invasion, the mechanisms underlying this acquisition remain unknown. Here,
Michael E. Chirgwin, Chelsea Gan, Karla P. Godinez-Macias, Kaitlyn Choe, Justine C. Shiau, Jaeson Calla, Dennis E. Kyle, Elizabeth A. Winzeler, Emily R. Derbyshire   +8 more
doaj   +1 more source

MOLECULAR ANALYSIS OF PBMSP-1 GENE IN ERYTHROCYTE OF MICE INFECTED WITH Plasmodium berghei

Jurnal Kedokteran Hewan, 2018
This study aimed to analyze MSP-1 gene in mice erythrocyte infected with Plasmodium berghei using polymerase chain reaction (PCR). The result showed the existence of 462 bp DNA band which was assumed to encode MSP-1 protein with molecular weight of 19 ...
Rosnizar Rosnizar, Kartini Eriani
doaj   +1 more source

Immunological Interactions Between Gammadelta T Cells and West Nile Virus in the Infected Host

Reviews in Medical Virology, Volume 36, Issue 4, July 2026.
ABSTRACT Between mosquitoes and birds, West Nile virus (WNV) is a neurotropic flavivirus, an arthropod‐borne pathogen involved in an enzootic cycle. Additionally, it can infect both people and horses, leading to severe illness. Since 1999, WNV has spread across North and South America, including Mexico and the Caribbean.
E. Cimini, E. Tartaglia, F. Cristofanelli, S. Gili, F. Maggi   +4 more
wiley   +1 more source

Gene disruption of Plasmodium falciparum p52 results in attenuation of malaria liver stage development in cultured primary human hepatocytes [PDF]

, 2008
Difficulties with inducing sterile and long lasting protective immunity against malaria with subunit vaccines has renewed interest in vaccinations with attenuated <i>Plasmodium</i> parasites.
Melissa R van Dijk, Ben C L van Schaijk, Geert-Jan van Gemert, Yalaoui Samir, Schaijk, B.C.L. van, Waters, A.P., van Gemert, G. J., Franetich Jean-Francois, Samir Yalaoui, Shahid M Khan, van de Vegte-Bolmera, M., Silvie, O., Hoffman, S. L., Franetich, J.F., van Gemert Geert-Jan, Janse, C.J., Vegte-Bolmer, M.G. van de, Yalaouic, S., Khan, S. M., Chris J Janse, Stephen L Hoffman, Sauerwein Robert W., Silvie Olivier, Sauerwein, R. W., Robert W Sauerwein, Andrew P Waters, Hoffman, S.L., van Dijk, M. R., Waters Andrew P., Sauerwein, R.W., Jean-Francois Franetich, Gemert, G.J.A. van, van de Vegte-Bolmer Marga, Khan, S.M., Olivier Silvie, Mazier, D., Gegoc, A., Gego, A., Khan Shahid M., Franetich, J. F., Dijk, M.R. van, Dominique Mazier, Audrey Gego, Yalaoui, S., Waters, A. P., Janse, C. J., van Schaijk Ben C. L., van Dijk Melissa R., van Schaijk, B. C. L., Janse Chris J., Gego Audrey, Mazier Dominique, Marga van de Vegte-Bolmer, Hoffman Stephen L.   +53 more
core   +3 more sources