Results 91 to 100 of about 90,646 (224)

Fluorescent Plasmodium berghei sporozoites and pre-erythrocytic stages: a new tool to study mosquito and mammalian host interactions with malaria parasites.

, 2001
To track malaria parasites for biological studies within the mosquito and mammalian hosts, we constructed a stably transformed clonal line of Plasmodium berghei, PbFluspo, in which sporogonic and pre-erythrocytic liver-stage parasites are autonomously ...
Ménard, R, Thathy, V, Mota, MM, Natarajan, R, Vernick, KD, Hafalla, JC   +5 more
core   +1 more source

Genetic recombination in Plasmodium berghei

Parasitology, 1973
Crosses have been made between two lines of Plasmodium berghei yoelii differing in drug-sensitivity and enzyme-type. The two lines used were line A, which is pyrimethamine-resistant and contains an electrophoretic form of glucose phosphate isomerase termed GPI-1, and line C, which is pyrimethamine-sensitive and contains enzyme-form GPI-2. Equal numbers
D, Walliker, R, Carter, S, Morgan
openaire   +2 more sources

Robust Bioconjugated Antigens Induce Immune Responses Preventing Malaria Infection and its Transmission

Small, Volume 22, Issue 28, 18 May 2026.
Engineered malaria antigens enable in vivo bioconjugation to submicron biopolymer particles in E. coli. Two antigens are co‐tethered at high density and defined stoichiometry. The resulting thermostable particles elicit strong, durable antibody and T‐cell responses, conferring robust protection and blocking mosquito transmission.
Nivethika Sivakumaran, Yevel Flores‐Garcia, Chanel M. Naar, Shuxiong Chen, Mili Mehta, Fijs W. B. van Leeuwen, Abhai Tripathi, Rajagopal Murugan, Meta Roestenberg, Fidel Zavala, Bernd H. A. Rehm   +10 more
wiley   +1 more source

Treadted Plasmodium berghei infected pregnant mice by – Andrographis paniculata tablet (AS201 – 01) decreasing the TLR -4 expression and apoptosis index of placental tissue [PDF]

Objective: This study aimed to evaluate the effect of Andrographis paniculata tablet (AS201-01) in decreasing expression of Toll-Like Receptor-4 (TLR-4) and apoptosis index of placental tissue of Plasmodium berghei infected pregnant mice.
Budi Prasetyo, Budi, Hilkatul Ilmi, -, Diantri Nari Ratih, -, Lidya Tumewu, -, Yustinasari, -, Aty Widyawaruyanti, -   +5 more
core   +1 more source

Antiplasmodial Effect of Anthocleista vogelii on Albino Mice Experimentally Infected with Plasmodium berghei berghei (NK 65)

Journal of Parasitology Research, 2014
The objective of the present study was to investigate the antiplasmodial effect of the ethanolic stem bark extract of Anthocleista vogelii at different doses in albino mice infected with Plasmodium berghei berghei (NK 65).
Lebari Barine Gboeloh, Okpok Eta Okon, Samuel Effiong Udoh   +2 more
doaj   +1 more source

Extracellular ATP triggers proteolysis and cytosolic Ca²⁺ rise in Plasmodium berghei and Plasmodium yoelii malaria parasites

Malaria Journal, 2012
Background Plasmodium has a complex cell biology and it is essential to dissect the cell-signalling pathways underlying its survival within the host. Methods Using the fluorescence resonance energy transfer (FRET) peptide substrate Abz-AIKFFARQ-EDDnp and
Cruz Laura, Juliano Maria, Budu Alexandre, Juliano Luiz, Holder Anthony A, Blackman Michael J, Garcia Célia RS   +6 more
doaj   +1 more source

New synchronization method for Plasmodium falciparum [PDF]

, 2010
<b>Background</b>: Plasmodium falciparum is usually asynchronous during in vitro culture. Although various synchronization methods are available, they are not able to narrow the range of ages of parasites.
Lisa C Ranford-Cartwright, Mwangi Jonathan M, Sinha Abhinav, Ranford-Cartwright Lisa C, Humphreys Georgina S, Georgina S Humphreys, Abhinav Sinha, Mwangi, J.M., Jonathan M Mwangi, Ranford-Cartwright, L.C., Sinha, A., Humphreys, G.S.   +11 more
core   +1 more source

In Vitro and In Vivo Antimalarial Activity of LZ1, a Peptide Derived from Snake Cathelicidin

Toxins, 2019
Antimalarial drug resistance is an enormous global threat. Recently, antimicrobial peptides (AMPs) are emerging as a new source of antimalarials. In this study, an AMP LZ1 derived from snake cathelicidin was identified with antimalarial activity.
Yaqun Fang, Xiaoqin He, Pengcheng Zhang, Chuanbin Shen, James Mwangi, Cheng Xu, Guoxiang Mo, Ren Lai, Zhiye Zhang   +8 more
doaj   +1 more source

IL35 modulation altered survival, cytokine environment and histopathological consequences during malaria infection in mice

Malaria Journal, 2019
Background The immune modulating potential of IL-35 in multiple human disorders has been reported. Consequent upon the recognition of inflammatory cytokine activation and its preponderance for mediating pathology during malaria infection, the study aimed
Ramatu Omenesa Bello, Maizaton Atmadini Abdullah, Roslaini Abd Majid, Voon Kin Chin, Mohammed Faruq Abd Rachman Isnadi, Zaid Osama Ibraheem, Mohd Khairi Hussain, Mohammed Garba Magaji, Rusliza Basir   +8 more
doaj   +1 more source

Suppression of adaptive immunity to heterologous antigens during Plasmodium infection through hemozoin-induced failure of dendritic cell function [PDF]

, 2005
Background: Dendritic cells (DCs) are central to the initiation and regulation of the adaptive immune response during infection. Modulation of DC function may therefore allow evasion of the immune system by pathogens. Significant depression of the host'
Owain R Millington, R Phillips, Di Lorenzo, Caterina, Phillips, R. Stephen, Millington, Owain R., Paul Garside, Brewer, James M., Caterina Di Lorenzo, Garside, Paul, James M Brewer, Brewer James M, Phillips R, Millington Owain R, Garside Paul, Di Lorenzo Caterina   +14 more
core   +1 more source