Antecedentes. En Colombia existen pocos estudios que buscan encontrar diferencias clínicas y parasitológicas en la malaria causada por Plasmodium falciparum y Plasmodium vivax. Objetivo.
Angélica Knudson Ospina+5 more
doaj +1 more source
Background Rapid diagnostic tests (RDT) are widely used for malaria diagnosis in Madagascar, where Plasmodium falciparum is the predominant species. Molecular diagnosis is essential for malaria surveillance, but requires additional blood samples for DNA ...
Voahangy Hanitriniaina I. Andrianaranjaka+7 more
doaj +1 more source
Case-control approach to identify Plasmodium falciparum polymorphisms associated with severe malaria. [PDF]
BACKGROUND: Studies to identify phenotypically-associated polymorphisms in the Plasmodium falciparum 23 Mb genome will require a dense array of marker loci.
Chokejindachai, Watcharee+1 more
core +7 more sources
Gametocytes: insights gained during a decade of molecular monitoring [PDF]
In vertebrate hosts, malaria parasites produce specialized male and female sexual stages (gametocytes). Soon after being taken up by a mosquito, gametocytes rapidly produce gametes and, once mated, they infect their vector and can be transmitted to new ...
Abdel-Wahab+81 more
core +2 more sources
Background A simple real-time PCR assay using one set of primer and probe for rapid, sensitive and quantitative detection of Plasmodium species, with simultaneous differentiation of Plasmodium falciparum from the three other Plasmodium species ...
Pistone Thierry+10 more
doaj +1 more source
Malaria in children of Tshimbulu (Western Kasai, Democratic Republic of the Congo): epidemiological data and accuracy of diagnostic assays applied in a limited resource setting [PDF]
BACKGROUND: The literature data on malaria in Western Kasai, DRC, are limited and inadequate. A recent molecular survey there has detected Plasmodium ovale and Plasmodium malariae as mixed infections with Plasmodium falciparum.
Bellina, Livia+6 more
core +2 more sources
Glycerol Inhibits Water Permeation through Plasmodium Falciparum Aquaglyceroporin [PDF]
Plasmodium falciparum aquaglyceroporin (PfAQP) is a multifunctional membrane protein in the plasma membrane of P. falciparum, the parasite that causes the most severe form of malaria. The current literature has established the science of PfAQP's structure, functions, and hydrogen-bonding interactions but left unanswered the following fundamental ...
arxiv +1 more source
Background: Malaria in Pakistan is a serious public health problem and thrombocytopenia can serve as diagnostic predictive marker. Objective: The objective of present study was to find out the frequency of plasmodium vivax and falciparum in malaria ...
Maliha Ajmal+5 more
doaj +2 more sources
Bacteria- and IMD pathway-independent immune defenses against Plasmodium falciparum in Anopheles gambiae. [PDF]
The mosquito Anopheles gambiae uses its innate immune system to control bacterial and Plasmodium infection of its midgut tissue. The activation of potent IMD pathway-mediated anti-Plasmodium falciparum defenses is dependent on the presence of the midgut ...
Benjamin J Blumberg+3 more
doaj +1 more source
Uptake of purines in Plasmodium falciparum-infected human erythrocytes is mostly mediated by the human Equilibrative Nucleoside Transporter and the human Facilitative Nucleobase Transporter [PDF]
<b>Background</b>: Plasmodium parasites are unable to synthesize purines de novo and have to salvage them from the host. Due to this limitation in the parasite, purine transporters have been an area of focus in the search for anti-malarial ...
De Koning, H.P.+2 more
core +4 more sources