Malaria adalah penyakit kronis dan akut yang disebabkan oleh protozoa dari jenis Plasmodium. Ada 4 spesies yang utama dari jenis plasmodium yang menyebabkan penyakit malaria pada manusia, yaitu: Plasmodium falciparum, Plasmodium vivax, Plasmodium ...
Nur Ain Banyal+2 more
doaj +1 more source
A Plasmodium falciparum host-targeting motif functions in export during blood stage infection of the rodent malarial parasite Plasmodium berghei. [PDF]
Plasmodium falciparum (P. falciparum) secretes hundreds of proteins--including major virulence proteins--into the host erythrocyte. In order to reach the host cytoplasm, most P. falciparum proteins contain an N terminal host-targeting (HT) motif composed
Julia J MacKenzie+4 more
doaj +1 more source
GAMETOCYTEMIA IN PLASMODIUM VIVAX AND PLASMODIUM FALCIPARUM INFECTIONS [PDF]
Two expert research microscopists, each blinded to the other's reports, diagnosed single-species malaria infections in 2,141 adults presenting at outpatient malaria clinics in Tak Province, Thailand, and Iquitos, Peru, in May-August 1998, May-July 1999, and May-June 2001.
Jeeraphat Sirichaisinthop+15 more
openaire +3 more sources
Construction of a Plasmodium falciparum Rab-interactome identifies CK1 and PKA as Rab-effector kinases in malaria parasites [PDF]
Background information The pathology causing stages of the human malaria parasite Plasmodium falciparum reside within red blood cells that are devoid of any regulated transport system.
Bourdoncle, P.+9 more
core +1 more source
Background Malaria and helminths share the same geographical distribution in tropical Africa. Studies of the interaction of helminth and malaria co-infection in humans have been few and are mainly epidemiological, with little information on cellular ...
Richard Bwanika+3 more
doaj +1 more source
Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine. [PDF]
Adequate clinical and parasitologic cure by artemisinin combination therapies relies on the artemisinin component and the partner drug. Polymorphisms in the Plasmodium falciparum chloroquine resistance transporter (pfcrt) and P.
Adam, Ishag+62 more
core +3 more sources
Structure and Drug Resistance of the Plasmodium falciparum Transporter PfCRT
The emergence and spread of drug-resistant Plasmodium falciparum impedes global efforts to control and eliminate malaria. For decades, treatment of malaria has relied on chloroquine (CQ), a safe and affordable 4-aminoquinoline that was highly effective ...
Jonathan Kim+17 more
semanticscholar +1 more source
Ecological immunology of mosquito-malaria interactions: Of non-natural versus natural model systems and their inferences [PDF]
There has been a recent shift in the literature on mosquito/Plasmodium interactions with an increasingly large number of theoretical and experimental studies focusing on their population biology and evolutionary processes.
Tripet, F
core +1 more source
cAMP-Signalling Regulates Gametocyte-Infected Erythrocyte Deformability Required for Malaria Parasite Transmission. [PDF]
Blocking Plasmodium falciparum transmission to mosquitoes has been designated a strategic objective in the global agenda of malaria elimination. Transmission is ensured by gametocyte-infected erythrocytes (GIE) that sequester in the bone marrow and at ...
A Dawn+74 more
core +16 more sources
Background Worldwide, the highest malaria mortality is due to Plasmodium falciparum infection. However, other species of Plasmodium (Plasmodium vivax, Plasmodium ovale, Plasmodium malariae, and Plasmodium knowlesi) can also cause malaria.
Hugo Kavunga-Membo+9 more
doaj +1 more source