PENGGUNAAN METODE ACTIVE CONTOUR UNTUK SEGMENTASI PARASIT MALARIA PLASMODIUM FALCIPARUM
Simetris: Jurnal Teknik Mesin, Elektro dan Ilmu Komputer, 2015 ABSTRAK Plasmodium falciparum merupakan penyebab malaria tropika atau malaria falciparum. Spesies ini paling berbahaya dibandingkan keempat spesies lainnya karena dapat menyebabkan komplikasi malaria serebral.
Endi Permata
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MEPicides: Potent antimalarial prodrugs targeting isoprenoid biosynthesis [PDF]
, 2017 The emergence of Plasmodium falciparum resistant to frontline therapeutics has prompted efforts to identify and validate agents with novel mechanisms of action. MEPicides represent a new class of antimalarials that inhibit enzymes of the methylerythritol
Brothers, Robert C +10 more
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Plasmodium falciparum Hop: Detailed analysis on complex formation with Hsp70 and Hsp90 [PDF]
Biochemical and Biophysical Research Communications 2015 vol 456
pp 440-445, 2013 The heat shock organizing protein (Hop) is important in modulating the activity and co-interaction of two chaperones: heat shock protein 70 and 90 (Hsp70 and Hsp90). Recent research suggested that Plasmodium falciparum Hop (PfHop), PfHsp70 and PfHsp90 form a complex in the trophozoite infective stage.
arxiv +1 more source
A model for malaria treatment evaluation in the presence of multiple species [PDF]
arXiv, 2022 Plasmodium (P.) falciparum and P. vivax are the two most common causes of malaria. While the majority of deaths and severe morbidity are due to P. falciparum, P. vivax poses a greater challenge to eliminating malaria outside of Africa due to its ability to form latent liver stage parasites (hypnozoites), which can cause relapsing episodes within an ...
arxiv
Разработка и регистрация лекарственных средств, 2022 Introduction. Malaria is the sixth leading cause of death worldwide. According to a WHO survey (2019-2020), the total number of malaria deaths is estimated to be 409000. Plasmodium falciparum and Plasmodium vivax are major malaria parasites, particularly
S. Sakpal +3 more
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Adaptation of translational machinery in malaria parasites to accommodate translation of poly-adenosine stretches throughout its life cycle [PDF]
, 2019 Malaria is caused by unicellular apicomplexan parasites of the ...
Djuranovic, Sergej +2 more
core +1 more source
Involvement of Plasmodium falciparum protein kinase CK2 in the chromatin assembly pathway [PDF]
, 2012 Background Protein kinase CK2 is a pleiotropic serine/threonine protein kinase with hundreds of reported substrates, and plays an important role in a number of cellular processes.
Chene, A. +11 more
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PLoS ONE, 2019 The ability to identify mixed-species infections and track the origin of Plasmodium parasites can further enhance the development of treatment and prevention recommendations as well as outbreak investigations.
Sarah E Schmedes +4 more
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Declining Burden of Plasmodium vivax in a Population in Northwestern Thailand from 1995 to 2016 before Comprehensive Primaquine Prescription for Radical Cure. [PDF]
, 2020 All Plasmodium cases have declined over the last decade in northwestern Thailand along the Myanmar border. During this time, Plasmodium vivax has replaced Plasmodium falciparum as the dominant species. The decline in P.
Carrara, Verena I +6 more
core
RNA-Seq analysis of splicing in Plasmodium falciparum uncovers new splice junctions, alternative splicing and splicing of antisense transcripts. [PDF]
, 2011 Over 50% of genes in Plasmodium falciparum, the deadliest human malaria parasite, contain predicted introns, yet experimental characterization of splicing in this organism remains incomplete.
DeRisi, Joseph L +2 more
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