Critical Steps of Plasmodium falciparum Ookinete Maturation [PDF]
The egress and fertilization of Plasmodium gametes and development of a motile ookinete are the first crucial steps that mediate the successful transmission of the malaria parasites from humans to the Anopheles vector. However, limited information exists
Alano, P.+5 more
core +1 more source
Plasmodium falciparum glutamate dehydrogenase a is dispensable and not a drug target during erythrocytic development [PDF]
<p>Background: Plasmodium falciparum contains three genes encoding potential glutamate dehydrogenases. The protein encoded by gdha has previously been biochemically and structurally characterized.
Aparicio, I.+7 more
core +4 more sources
The ability to identify mixed-species infections and track the origin of Plasmodium parasites can further enhance the development of treatment and prevention recommendations as well as outbreak investigations.
Sarah E Schmedes+4 more
doaj +1 more source
PENGGUNAAN METODE ACTIVE CONTOUR UNTUK SEGMENTASI PARASIT MALARIA PLASMODIUM FALCIPARUM
ABSTRAK Plasmodium falciparum merupakan penyebab malaria tropika atau malaria falciparum. Spesies ini paling berbahaya dibandingkan keempat spesies lainnya karena dapat menyebabkan komplikasi malaria serebral.
Endi Permata
doaj +1 more source
A well-conserved Plasmodium falciparum var gene shows an unusual stage-specific transcript pattern [PDF]
The var multicopy gene family encodes Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) variant antigens, which, through their ability to adhere to a variety of host receptors, are thought to be important virulence factors.
Sue A. Kyes+51 more
core +1 more source
Anaemia of Plasmodium falciparum malaria
The pathophysiology of the anaemia of falciparum malaria is both complex and multifactorial, and results in a condition which is a major cause of mortality and morbidity in patients, especially children and pregnant women, living in malarial endemic areas.
Phillips, R, Pasvol, G
openaire +3 more sources
Bacteria- and IMD pathway-independent immune defenses against Plasmodium falciparum in Anopheles gambiae. [PDF]
The mosquito Anopheles gambiae uses its innate immune system to control bacterial and Plasmodium infection of its midgut tissue. The activation of potent IMD pathway-mediated anti-Plasmodium falciparum defenses is dependent on the presence of the midgut ...
Benjamin J Blumberg+3 more
doaj +1 more source
Declining Burden of Plasmodium vivax in a Population in Northwestern Thailand from 1995 to 2016 before Comprehensive Primaquine Prescription for Radical Cure. [PDF]
All Plasmodium cases have declined over the last decade in northwestern Thailand along the Myanmar border. During this time, Plasmodium vivax has replaced Plasmodium falciparum as the dominant species. The decline in P.
Carrara, Verena I+6 more
core
Genetic and genomic approaches for the discovery of parasite genes involved in antimalarial drug resistance [PDF]
The biggest threat to the war on malaria is the continued evolution of drug resistance by the parasite. Resistance to almost all currently available antimalarials now exists in Plasmodium falciparum which causes the most suffering among all human malaria
Mwangi, J.M., Ranford-Cartwright, L.C.
core +1 more source
Soft Nanocarriers as Antimicrobial Co‐Delivery Systems to Combat Resistant Infections
Soft nanocarrier‐based co‐delivery systems present a versatile and promising platform for combating antimicrobial resistance (AMR) by enabling spatiotemporally controlled, pathogen‐specific drug release. Their tunable physicochemical properties allow for the co‐encapsulation of synergistic antimicrobial agents, optimization of drug ratios, and surface ...
Anamarija Nikoletic+5 more
wiley +1 more source