Results 61 to 70 of about 287,184 (330)

The role of Plasmodium falciparum var genes in malaria in pregnancy [PDF]

, 2004
Sequestration of Plasmodium falciparum-infected erythrocytes in the placenta is responsible for many of the harmful effects of malaria during pregnancy. Sequestration occurs as a result of parasite adhesion molecules expressed on the surface of infected ...
Andrews, Baruch, Beeson, Beeson, Beeson, Brabin, Buffet, Chen, Costa, Creasey, Dorman, Duffy, Duffy, Flick, Freitas-Junior, Fried, Fried, Fried, Fried, Gardner, Jensen, Kyes, Kyes, Lekana Douki, McCormick, McGregor, Menendez, Menendez, Nosten, O'Neil-Dunne, Reeder, Reeder, Ricke, Rowe, Rowe, Salanti, Salanti, Shulman, Smith, Smith, Smith, Smith, Staalsoe, Staalsoe, Steketee, Su, Suguitan, Taylor, Taylor, Walter, Ward, Winter   +51 more
core   +1 more source

Comparative transcriptomic analysis of the malaria parasites Plasmodium falciparum and Plasmodium vivax sensitive and resistant strains

Разработка и регистрация лекарственных средств, 2022
Introduction. Malaria is the sixth leading cause of death worldwide. According to a WHO survey (2019-2020), the total number of malaria deaths is estimated to be 409000. Plasmodium falciparum and Plasmodium vivax are major malaria parasites, particularly
S. Sakpal, S. Z. Abdeen, Sh. L. Kothari, V. Bastikar   +3 more
doaj   +1 more source

Detecting signatures of balancing selection to identify targets of anti-parasite immunity.

, 2010
Parasite antigen genes might evolve under frequency-dependent immune selection. The distinctive patterns of polymorphism that result can be detected using population genetic methods that test for signatures of balancing selection, allowing genes encoding
Conway, David J, Weedall, Gareth D
core   +1 more source

Artemether resistance in vitro is linked to mutations in PfATP6 that also interact with mutations in PfMDR1 in travellers returning with Plasmodium falciparum infections. [PDF]

, 2012
BACKGROUND: Monitoring resistance phenotypes for Plasmodium falciparum, using in vitro growth assays, and relating findings to parasite genotype has proved particularly challenging for the study of resistance to artemisinins.
Khairnar, K, Krishna, S, Lau, R, Lepore, R, Pillai, DR, Staines, HM, Via, A   +6 more
core   +1 more source

Evidence of Artemisinin-Resistant Plasmodium falciparum Malaria in Eastern India.

New England Journal of Medicine, 2018
Artemisinin Resistance in India In this study, possible resistance mutations and parasite survival among Plasmodium falciparum isolates obtained from patients in West Bengal, India, were investigat...
Sabyasachi Das, B. Saha, A. K. Hati, Somenath Roy   +3 more
semanticscholar   +1 more source

New synchronization method for Plasmodium falciparum [PDF]

, 2010
<b>Background</b>: Plasmodium falciparum is usually asynchronous during in vitro culture. Although various synchronization methods are available, they are not able to narrow the range of ages of parasites.
Abhinav Sinha, C Lambros, EA Nillni, G Pasvol, Georgina S Humphreys, HC Hoppe, J Inselburg, J Lelievre, JA Naughton, JB Jensen, JD Haynes, JD Haynes, JE Mrema, Jonathan M Mwangi, Lisa C Ranford-Cartwright, SB Aley, SY Ahn, W Trager   +17 more
core   +4 more sources

Using the Plasmodium mitochondrial genome for classifying mixed-species infections and inferring the geographical origin of P. falciparum parasites imported to the U.S.

PLoS ONE, 2019
The ability to identify mixed-species infections and track the origin of Plasmodium parasites can further enhance the development of treatment and prevention recommendations as well as outbreak investigations.
Sarah E Schmedes, Dhruviben Patel, Julia Kelley, Venkatachalam Udhayakumar, Eldin Talundzic   +4 more
doaj   +1 more source

PENGGUNAAN METODE ACTIVE CONTOUR UNTUK SEGMENTASI PARASIT MALARIA PLASMODIUM FALCIPARUM

Simetris: Jurnal Teknik Mesin, Elektro dan Ilmu Komputer, 2015
ABSTRAK Plasmodium falciparum merupakan penyebab malaria tropika atau malaria falciparum. Spesies ini paling berbahaya dibandingkan keempat spesies lainnya karena dapat menyebabkan komplikasi malaria serebral.
Endi Permata
doaj   +1 more source

Bacteria- and IMD pathway-independent immune defenses against Plasmodium falciparum in Anopheles gambiae. [PDF]

PLoS ONE, 2013
The mosquito Anopheles gambiae uses its innate immune system to control bacterial and Plasmodium infection of its midgut tissue. The activation of potent IMD pathway-mediated anti-Plasmodium falciparum defenses is dependent on the presence of the midgut ...
Benjamin J Blumberg, Stefanie Trop, Suchismita Das, George Dimopoulos   +3 more
doaj   +1 more source

Antimalarial pantothenamide metabolites target acetyl–coenzyme A biosynthesis in Plasmodium falciparum

Science Translational Medicine, 2019
Pantothenamides form antimetabolites that interfere with acetyl-CoA metabolism in the human malaria parasite Plasmodium falciparum. Development of a new antimalarial drug Pantothenenic acid, or vitamin B5, is an essential nutrient for the deadly malaria ...
J. Schalkwijk, Erik L. Allman, P. Jansen, Laura E. de Vries, Julie M. J. Verhoef, S. Jackowski, Peter N. M. Botman, Christien A. Beuckens-Schortinghuis, Karin M. J. Koolen, J. Bolscher, Martijn W. Vos, K. Miller, Stacy A. Reeves, Helmi E Pett, G. Trevitt, S. Wittlin, C. Scheurer, Sibylle Sax, Christoph Fischli, Iñigo Angulo-Barturen, M. Jiménez-Díaz, G. Josling, T. Kooij, Roger Bonnert, B. Campo, R. Blaauw, F. Rutjes, R. Sauerwein, M. Llinás, P. Hermkens, K. Dechering   +30 more
semanticscholar   +1 more source