Results 61 to 70 of about 100,185 (210)

Host‐associated beneficial gut microbiota boosts induced immunity and limits immune deployment costs in bumblebees

Journal of Animal Ecology, EarlyView.
Our work demonstrates a key role for host‐associated microbiota in the realization of induced immune defense, and contributes more broadly to our understanding of microbiota‐immune interactions in the context of ecological immunology. Abstract Ecological immunology posits that variation in host resistance to infection may be attributed partly to the ...
Austin C. Calhoun, Teni Shosanya, Brenna K. Long, Jade K. Rehberger, Ben M. Sadd   +4 more
wiley   +1 more source

Investigation on possible transmission of monkeys' Plasmodium to human in a populations living in the equatorial rainforest of the Democratic republic of Congo

International Journal for Parasitology: Parasites and Wildlife, 2016
Plasmodiums are protozoa that may infect various hosts. Only five species are now recognized as naturally parasitizing humans: Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae, Plasmodium ovale and Plasmodium knowlesi.
Dieudonné Makaba Mvumbi, Thierry Lengu Bobanga, Solange Efundu Umesumbu, Billy Shako Kunyu, Jean-Marie Ntumba Kayembe, Nani-Tuma H. Situakibanza, Georges Lelo Mvumbi, Pierrette Melin, Patrick De Mol, Marie-Pierre Hayette   +9 more
doaj   +1 more source

Population pharmacokinetics of lumefantrine in pregnant and non‐pregnant women with uncomplicated Plasmodium falciparum malaria in Western Kenya

British Journal of Clinical Pharmacology, EarlyView.
Aim This study intends to assess the pharmacokinetic properties and treatment response of lumefantrine in pregnant and non‐pregnant women with uncomplicated Plasmodium falciparum malaria infection in Western Kenya. Methods Seventy‐five women with uncomplicated P.
Elizabeth Juma, Junjie Ding, Martin Ongas, Nelly Koskei, Kevin Onyango, Florence Oloo, Rashid Aman, Gilbert Kokwaro, Joel Tarning, Bernhards Ogutu   +9 more
wiley   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

Detection of high frequency of MAD20 allelic variants of Plasmodium falciparum merozoite surface protein 1 gene from Adama and its surroundings, Oromia, Ethiopia [PDF]

, 2021
Temesgen File, Tsegaye Chekol, Gezahegn Solomon, Hunduma Dinka, Lemu Golassa   +4 more
openalex   +1 more source

Evolutionary divergence and functional insights into the heteromeric cis‐prenyltransferase of Paramecium tetraurelia

The FEBS Journal, EarlyView.
Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk, Kamil Steczkiewicz, Mariusz Radkiewicz, Paweł Link‐Lenczowski, Przemysław Surowiecki, Karolina Sztompka, Kariona A. Grabińska, Jacek K. Nowak, Liliana Surmacz   +8 more
wiley   +1 more source

Highly divergent apicomplexan cytoskeletons provide additional models for actin biology

The FEBS Journal, EarlyView.
Actin is a highly conserved, abundant and central molecule in eukaryotes. Apicomplexans contain some of the most sequence‐divergent actin cytoskeletons known. This divergence results in overlapping yet different biochemical properties. Here, we highlight the remarkable divergence of the actin cytoskeleton by comparing apicomplexan to classical systems,
Yukino Kobayashi, Ross G. Douglas
wiley   +1 more source

Plasmodium falciparum rosetting is associated with malaria severity in Kenya [PDF]

, 1995
J. Alexandra Rowe, J Obeiro, Chris Newbold, Kevin Marsh   +3 more
openalex   +1 more source

Protein tandem repeats that produce frameshifts can generate new structural states and functions

The FEBS Journal, EarlyView.
We explored an alternative protein structure landscape by analyzing amino acid sequences from frameshifted tandem repeats—regions prone to frameshifts. These frameshifts, especially in short repeats, lead to more drastic changes than in non‐repetitive regions, often altering structure, function, localization, and potentially contributing to disease ...
Zarifa Osmanli, Gudrun Aldrian, Jeremy Leclercq, Theo Falgarone, Santiago M. Gómez Bergna, Denis N. Prada Gori, Andrew V. Oleinikov, Ilham Shahmuradov, Andrey V. Kajava   +8 more
wiley   +1 more source

Assessing the burden of submicroscopic Plasmodium infections in a pre-elimination malaria setting in sub-Saharan Africa, Guinea-Bissau

Malaria Journal
Background Submicroscopic Plasmodium infections can be a source of persistent malaria transmission. The aim of this study was to assess their frequency, distribution, morbidity and associated factors in a pre-elimination malaria setting in sub-Saharan ...
Ronise Silva, Luis Filipe Lopes, Amabelia Rodrigues, Ana Paula Arez, Márcia M. Medeiros   +4 more
doaj   +1 more source