Results 61 to 70 of about 302,576 (367)
Probing Plasmodium falciparum sexual commitment at the single-cell level [PDF]
, 2018 Background: Malaria parasites go through major transitions during their complex life cycle, yet the underlying differentiation pathways remain obscure.
Birren, Bruce W. +8 more
core +4 more sources
Plasmodium falciparum biosynthesizes sulfoglycosphingolipids
Molecular and Biochemical Parasitology, 2007 Sulfated glycosphingolipids are present on the surface of a variety of cells. They are active participants in adhesion processes in many systems and appear to be involved in the regulation of cell proliferation, differentiation and other developmental cellular events.
Landoni, Malena +6 more
openaire +3 more sources
Protein Sorting in Plasmodium Falciparum [PDF]
Life, 2021 Plasmodium falciparum is a unicellular eukaryote with a very polarized secretory system composed of micronemes rhoptries and dense granules that are required for host cell invasion. P. falciparum, like its relative T. gondii, uses the endolysosomal system to produce the secretory organelles and to ingest host cell proteins.
openaire +3 more sources
Разработка и регистрация лекарственных средств, 2022 Introduction. Malaria is the sixth leading cause of death worldwide. According to a WHO survey (2019-2020), the total number of malaria deaths is estimated to be 409000. Plasmodium falciparum and Plasmodium vivax are major malaria parasites, particularly
S. Sakpal +3 more
doaj +1 more source
Rocaglates as dual-targeting agents for experimental cerebral malaria [PDF]
, 2018 Cerebral malaria (CM) is a severe and rapidly progressing complication of infection by Plasmodium parasites that is associated with high rates of mortality and morbidity.
Ayi, Kodjo +12 more
core +1 more source
Plasmodium falciparum Containment Strategy [PDF]
Medical Journal Armed Forces India, 2008 World Health Organization (WHO) estimates 1.7-2.5 million deaths and 300-500 million cases of malaria each year globally. As an initiative WHO has announced Roll Back Malaria (RBM) programme aimed at 50% reduction in deaths due to malaria by 2010. The RBM strategy recommends combination approach with prevention, care, creating sustainable demand for ...
openaire +2 more sources
Structure and Drug Resistance of the Plasmodium falciparum Transporter PfCRT
Nature, 2019 The emergence and spread of drug-resistant Plasmodium falciparum impedes global efforts to control and eliminate malaria. For decades, treatment of malaria has relied on chloroquine (CQ), a safe and affordable 4-aminoquinoline that was highly effective ...
Jonathan Kim +17 more
semanticscholar +1 more source
Major subpopulations of Plasmodium falciparum in sub-Saharan Africa
Science, 2019 Ebb and flow of parasite populations The population genetics of the malaria parasite Plasmodium falciparum across Africa is poorly understood but important to know for grasping the risks and dynamics of the spread of drug resistance. Harnessing the power
A. Amambua-Ngwa +20 more
semanticscholar +1 more source
Revista de la Facultad de Medicina, 2015 Antecedentes. En Colombia existen pocos estudios que buscan encontrar diferencias clínicas y parasitológicas en la malaria causada por Plasmodium falciparum y Plasmodium vivax. Objetivo.
Angélica Knudson Ospina +5 more
doaj +1 more source
Recent advances in malaria genomics and epigenomics [PDF]
, 2016 Malaria continues to impose a significant disease burden on low- and middle-income countries in the tropics. However, revolutionary progress over the last 3 years in nucleic acid sequencing, reverse genetics, and post-genome analyses has generated step ...
Kirchner, Sebastian +2 more
core +1 more source