Results 61 to 70 of about 71,751 (194)

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, Volume 13, Issue 13, 3 March 2026.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

Peroxisome Proliferator-Activator Receptor γ: A Link between Macrophage CD36 and Inflammation in Malaria Infection

PPAR Research, 2012
Severe malaria infection caused by Plasmodium falciparum is a global life-threatening disease and a leading cause of death worldwide. Intensive investigations have demonstrated that macrophages play crucial roles in control of inflammatory and immune ...
Yi Ren
doaj   +1 more source

Malaria in Bangladesh, 2000–2025: Navigating the Headwinds From Control to Elimination

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Bangladesh has dramatically reduced its malaria burden since 2000, confining the disease to specific geographic zones. However, the national 2030 elimination goal is now threatened by a complex interplay of biological, ecological, and social factors.
Abdullaha Al Mamun, Mustafa Sarwar A. Kayenat, K. A. M. Inzamul Islam   +2 more
wiley   +1 more source

Identification of conserved cross-species B-cell linear epitopes in human malaria: a subtractive proteomics and immuno-informatics approach targeting merozoite stage proteins

Frontiers in Immunology
Human malaria, caused by five Plasmodium species (P. falciparum, P. vivax, P. malariae, P. ovale, and P. knowlesi), remains a significant global health burden. While most interventions target P.
Sebastian D. Musundi, Jesse Gitaka, Bernard N. Kanoi   +2 more
doaj   +1 more source

Plasmodium Parasitemia and Its Relationship With Hematological, Liver, and Kidney Function of Patients With Falciparum Malaria in the Eastern Region, Ghana

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background Malaria remains a significant public health challenge in Sub‐Saharan Africa, including Ghana. Children and adults present with varying clinical and biochemical pictures in response to Plasmodium infection. Thus, the study aimed to explore the relationship between Plasmodium parasitemia and hematological, liver, and kidney function ...
Augustine Badu, Isaac Darban, Kofi Mensah, Maxwell Hubert Antwi, Mark Appeaning, Aaron Siaw Kwakye, Tonnies Abeku Buckman, Vidic Kwarteng Owusu, Daniel Takyi Mintah, Raymond Ansah Agyei, Comfort Yeboah, Daniel Acorlor   +11 more
wiley   +1 more source

Global distribution and contexts of interactions between humans and non‐human primates: A systematic review

People and Nature, Volume 8, Issue 3, Page 551-568, March 2026.
Abstract Understanding the frequency and socio‐ecological drivers of contacts between humans and non‐human primates (NHPs) is crucial for enhancing coexistence that favours NHP conservation, while limiting negative consequences such as aggressions and cross‐species disease transmission.
Cristina Caparrós‐Vallcorba, Filipe Vieira Santos de Abreu, Claudio Azat, Julio A. Benavides   +3 more
wiley   +1 more source

Epidemiological data of falciparum malaria in Ado-Odo/Ota, Southwest Ogun State, Nigeria

Data in Brief, 2018
In this data article, Blood and corresponding saliva samples from subjects presenting with fever and parasetaemia ≥2000 were obtained from selected hospitals in Ado-Odo/Ota, Ogun State over a period of two years and analyzed using Polymerase chain ...
I.Ruth Diji-geske, I.Grace Olasehinde, Irawo Fadinad, Damola Arogundade, Precious Darby   +4 more
doaj   +1 more source

Plasmodium falciparum virulence determinants unveiled.

Genome biology, 2002
The human malaria parasite Plasmodium falciparum, one of the world's most devastating pathogens, has an astonishing array of sequences and genes that play key roles in pathogenesis and immune evasion. We must understand the functions of these elements if the chronicity and unpredictable virulence of Plasmodium is to be explained.
Crabb, BS, Cowman, AF
openaire   +3 more sources

Population pharmacokinetics of lumefantrine in pregnant and non‐pregnant women with uncomplicated Plasmodium falciparum malaria in Western Kenya

British Journal of Clinical Pharmacology, Volume 92, Issue 3, Page 911-921, March 2026.
Aim This study intends to assess the pharmacokinetic properties and treatment response of lumefantrine in pregnant and non‐pregnant women with uncomplicated Plasmodium falciparum malaria infection in Western Kenya. Methods Seventy‐five women with uncomplicated P.
Elizabeth Juma, Junjie Ding, Martin Ongas, Nelly Koskei, Kevin Onyango, Florence Oloo, Rashid Aman, Gilbert Kokwaro, Joel Tarning, Bernhards Ogutu   +9 more
wiley   +1 more source

Genetic association between the Pfk13 gene mutation and artemisinin resistance phenotype in Plasmodium falciparum isolates from Yunnan Province, China

Malaria Journal, 2018
Background The problem of anti-malarial drug resistance is a long-term challenge faced by malaria control in Yunnan Province. Recently, the detection rates of chloroquine-resistant molecular markers (Plasmodium falciparum chloroquine resistant ...
Ying Dong, Jian Wang, Aiming Sun, Yan Deng, Mengni Chen, Yanchun Xu, Jingpo Xue   +6 more
doaj   +1 more source