Results 111 to 120 of about 36,588 (218)

Disruption of the Plasmodium falciparum Life Cycle through Transcriptional Reprogramming by Inhibitors of Jumonji Demethylases [PDF]

, 2020
Krista A. Matthews, Kossi M. Senagbe, Christopher Nötzel, Christopher A. Gonzales, Xinran Tong, Filipa Rijo‐Ferreira, Natarajan V. Bhanu, Celia Miguel-Blanco, María José Lafuente-Monasterio, Benjamin A. García, Björn F.C. Kafsack, Elisabeth D. Martínez   +11 more
openalex   +1 more source

Activity of Plasmodium vivax promoter elements in Plasmodium knowlesi , and a centromere-containing plasmid that expresses NanoLuc throughout the parasite life cycle [PDF]

, 2021
Roberto R. Moraes Barros, Kittisak Thawnashom, Tyler J. Gibson, Jennifer S. Armistead, Ramoncito L. Caleon, Miho Kaneko, Whitney A. Kite, J. Patrick Mershon, Jacqueline Brockhurst, Theresa Engels, Lynn Lambert, Sachy Orr-Gonzalez, John H. Adams, Juliana M. Sá, Osamu Kaneko, Thomas E. Wellems   +15 more
openalex   +1 more source

Host–parasite oxidative arms race: who will win?

Journal of Avian Biology, Volume 2026, Issue 1, January 2026.
Avian haemosporidian parasites are globally widespread with a broad repertoire of hosts. When infected, the host can either reduce (resistance) and/or limit the severity of parasitaemia (tolerance). Oxidative stress plays a pivotal role in the host's resistance and tolerance, as well as its detrimental endpoints.
Caroline Isaksson, Vaidas Palinauskas, Amparo Herrera Duenas, Olof Hellgren   +3 more
wiley   +1 more source

Novel Inhibitors of Plasmodium Phosphatidylinositol 4-kinase IIIβ with Low Propensity for Resistance: Life Cycle Stage Activity and In Vivo Efficacy in a Humanized Mouse Malaria Infection Model [PDF]

Godwin Akpeko Dziwornu, Mmakwena M. Mmonwa, Dina Coertzen, Liezl Krugmann, Nicolaas Salomane, Meta Leshabane, J. Thomas, Shanté da Rocha, Janette Reader, Keabetswe Masike, Mathew Njoroge, Nicole Sevilleno, Rachael Coyle, Nonlawat Boonyalai, Emily Mayville, Lee M, David A. Fidock, Lauren B. Coulson, John G. Woodland, Kathryn J. Wicht, Sandeep R. Ghorpade, Lyn‐Marié Birkholtz, Kelly Chibale   +22 more
openalex   +1 more source

Therapeutic Perspectives of SIRT6 Regulation: Computational Analysis of Activation and Inhibition by Bioactive Molecules

Journal of Molecular Recognition, Volume 39, Issue 1, January 2026.
ABSTRACT Sirtuin 6 (SIRT6) is an enzyme belonging to the class of nicotinamide adenine dinucleotide (NAD+) dependent histone deacetylases. It has been of interest due to its multivariate biological role and association with aging‐related diseases and metabolic dysfunctions.
Érika Geicianny de Carvalho Matias, Katyanna Sales Bezerra, Washington Sales Clemente Junior, Jonas Ivan Nobre Oliveira, Douglas Soares Galvão, Umberto Laino Fulco   +5 more
wiley   +1 more source

A Knockout Screen of ApiAP2 Genes Reveals Networks of Interacting Transcriptional Regulators Controlling the Plasmodium Life Cycle. [PDF]

Cell Host Microbe, 2017
Modrzynska K, Pfander C, Chappell L, Yu L, Suarez C, Dundas K, Gomes AR, Goulding D, Rayner JC, Choudhary J, Billker O.   +10 more
europepmc   +1 more source

Is Toxoplasma gondii‐secreted Protein With an Altered Thrombospondin Repeat (TgSPATR) a Potential Candidate for Immunisation? An Immunoinformatics‐Based Analysis

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
Toxoplasma gondii‐secreted protein with an altered thrombospondin repeat was computationally characterised as an immunogenic, non‐allergenic protein carrying multiple B‐ and T‐cell epitopes. Structural validation and immune simulation suggest its strong potential as a vaccine candidate against toxoplasmosis.
Masoud Foroutan, Elaheh Karimzadeh‐Soureshjani, Fatemeh Ghaffarifar   +2 more
wiley   +1 more source

The salivary glands and saliva of Anopheles gambiae as an essential step in the Plasmodium life cycle: A global proteomic study

, 2007
Valérie Choumet, Annick Carmi–Leroy, Christine Laurent, Pascal Lenormand, Jean‐Claude Rousselle, Abdelkader Namane, Charles W. Roth, Paul T. Brey   +7 more
openalex   +2 more sources

Additional file 1 of Analysis of pir gene expression across the Plasmodium life cycle

, 2021
Timothy S. Little, Deirdre Cunningham, Audrey Vandomme, Carlos Talavera‐López, Sarah Amis, Christopher Alder, John Addy, Sarah McLaughlin, Caroline Hosking, George K. Christophides, Adam J. Reid, Jean Langhorne   +11 more
openalex   +1 more source

Energetic and oxidative costs of microfilarial infection: evidence for fitness trade‐offs in male village weavers of the Amurum Forest Reserve

Wildlife Biology, Volume 2026, Issue 1, January 2026.
Microfilariae contribute to a higher energetic demand that could lead to oxidative damage and reduce hosts' fitness. Yet reports about the energy status and oxidative stress‐defense mechanisms of infected wild birds are rarely documented. We investigated the relationship between microfilariae and the energy status and oxidative damage‐defense ...
Felix A. Andong, Olufemi Olasoji, Ezekiel S. Mayowa, Praise O. Nwanozie, Emmanuel E. Osayi, Vincent C. Ejere, Abdifatah Ahmed A. Afyare   +6 more
wiley   +1 more source