Results 141 to 150 of about 530,210 (299)

mosGILT antibodies interfere with Plasmodium sporogony in Anopheles gambiae

Nature Communications
Plasmodium, the causative agents of malaria, are obtained by mosquitoes from an infected human. Following Plasmodium acquisition by Anopheles gambiae, mosquito gamma-interferon-inducible lysosomal thiol reductase (mosGILT) plays a critical role in its ...
Brady Dolan, Tomás Correa Gaviria, Yuemei Dong, Peter Cresswell, George Dimopoulos, Yu-Min Chuang, Erol Fikrig   +6 more
doaj   +1 more source

Experimental Evidence That Blood Parasite Infection Affects Incubation Patterns in a Cavity‐Nesting Songbird

Integrative Zoology, EarlyView.
Chronic blood parasite infections in wild birds can affect their incubation behavior. In pied flycatchers, females with reduced parasite infections incubated for longer than control females. Despite behavioral changes, no immediate effects on fitness were observed.
Marina García‐del Río, Santiago Merino, Julia Chércoles‐Nieto, Davide Baldan, Manuel Fuertes‐Recuero, Alejandro Cantarero   +5 more
wiley   +1 more source

Expanding the fluorescent toolkit: Blue fluorescent protein-expressing Plasmodium berghei for enhanced multiplex microscopy.

PLoS ONE
Fluorescent proteins are widely used as markers to differentiate genetically modified cells from their wild-type counterparts. In malaria research, the prevalent fluorescent markers include red fluorescent proteins (RFPs) and their derivatives, such as ...
Kodzo Atchou, Reto Caldelari, Magali Roques, Jacqueline Schmuckli-Maurer, Raphael Beyeler, Volker Heussler   +5 more
doaj   +1 more source

Humanized HLA-DR4.RagKO.IL2RγcKO.NOD (DRAG) mice sustain the complex vertebrate life cycle of Plasmodium falciparum malaria

Malaria Journal, 2014
BackgroundMalaria is a deadly infectious disease affecting millions of people in tropical and sub-tropical countries. Among the five species of Plasmodium parasites that infect humans, Plasmodium falciparum accounts for the highest morbidity and ...
Wathsala Wijayalath, S. Majji, E. Villasante, T. Brumeanu, T. Richie, S. Casares   +5 more
semanticscholar   +1 more source

A New Species of Plasmodium of the Subgenus Novyella Infecting White‐Shouldered Fire‐Eyes (Pyriglena leucoptera) (Aves: Thamnophilidae) in Brazil

Integrative Zoology, EarlyView.
South America has a remarkable genetic diversity of avian haemosporidians, yet only a few species have been described combining molecular and morphological data. This study introduces Plasmodium (Novyella) pyriglenae sp. nov., a new species infecting the white‐shouldered fire‐eye (Pyriglena leucoptera) in Brazil.
Luiz Gustavo Magalhães Alves, Pedro Henrique Oliveira Pereira, Vitória Loiola Batista, Leonardo Esteves Lopes, Érika Martins Braga   +4 more
wiley   +1 more source

Enrichment of Helminth Mitochondrial Genomes From Faecal Samples Using Hybridisation Capture

Molecular Ecology Resources, EarlyView.
ABSTRACT New approaches are urgently needed to enrich rare or low‐abundant DNA in complex samples. Soil‐transmitted helminths (STHs) inhabit heterogeneous environments, including the gastrointestinal tract of their host as adults and are excreted as eggs and larvae in faeces, complicating our understanding of their biology and the use of genetic tools ...
Marina Papaiakovou, Andrea Waeschenbach, Roy M. Anderson, Piet Cools, Zeleke Mekonnen, D. Timothy J. Littlewood, Cinzia Cantacessi, Stephen R. Doyle   +7 more
wiley   +1 more source

Dynamic Epigenetic Regulation of Gene Expression during the Life Cycle of Malaria Parasite Plasmodium falciparum

PLoS Pathogens, 2013
Epigenetic mechanisms are emerging as one of the major factors of the dynamics of gene expression in the human malaria parasite, Plasmodium falciparum. To elucidate the role of chromatin remodeling in transcriptional regulation associated with the progression of the P. falciparum intraerythrocytic development cycle (IDC), we mapped the temporal pattern
Gupta A.P., Chin W.H., Zhu L., Mok S., Luah Y.-H., Lim E.-H., Bozdech Z.   +6 more
openaire   +5 more sources

Evolutionary divergence and functional insights into the heteromeric cis‐prenyltransferase of Paramecium tetraurelia

The FEBS Journal, EarlyView.
Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk, Kamil Steczkiewicz, Mariusz Radkiewicz, Paweł Link‐Lenczowski, Przemysław Surowiecki, Karolina Sztompka, Kariona A. Grabińska, Jacek K. Nowak, Liliana Surmacz   +8 more
wiley   +1 more source

New insight into avian malaria vectors in New Zealand

Parasites & Vectors
Background Mosquitoes (Culicidae) are vectors for most malaria parasites of the Plasmodium species and are required for Plasmodium spp. to complete their life cycle.
E. R. Schoener, D. M. Tompkins, L. Howe, I. C. Castro   +3 more
doaj   +1 more source

Highly divergent apicomplexan cytoskeletons provide additional models for actin biology

The FEBS Journal, EarlyView.
Actin is a highly conserved, abundant and central molecule in eukaryotes. Apicomplexans contain some of the most sequence‐divergent actin cytoskeletons known. This divergence results in overlapping yet different biochemical properties. Here, we highlight the remarkable divergence of the actin cytoskeleton by comparing apicomplexan to classical systems,
Yukino Kobayashi, Ross G. Douglas
wiley   +1 more source