Results 251 to 260 of about 530,210 (299)

Single-cell views of the Plasmodium life cycle.

Trends in Parasitology, 2022
Malaria-causing Plasmodium parasites undergo multiple phenotypic transitions as they cycle between diverse niches in the mammalian and mosquito hosts. Recent applications of single-cell technologies to Plasmodium have enabled the systematic investigation of the distinct stages across the life cycle.
Eliana Real, Liliana Mancio-Silva
semanticscholar   +4 more sources

A Comprehensive Survey of the Plasmodium Life Cycle by Genomic, Transcriptomic, and Proteomic Analyses

Science, 2005
Plasmodium berghei and Plasmodium chabaudi are widely used model malaria species. Comparison of their genomes, integrated with proteomic and microarray data, with the genomes of Plasmodium falciparum and Plasmodium yoelii revealed a conserved core of 4500
N. Hall, M. Karras, J. Raine, J. Carlton, Taco W. A. Kooij, M. Berriman, L. Florens, C. Janssen, A. Pain, G. Christophides, K. James, Kim M Rutherford, B. Harris, D. Harris, C. Churcher, M. Quail, D. Ormond, J. Doggett, H. Trueman, J. Mendoza, Shelby L. Bidwell, M. Rajandream, D. Carucci, J. Yates, F. Kafatos, C. Janse, B. Barrell, C. Turner, A. Waters, R. Sinden   +29 more
semanticscholar   +4 more sources

Plasmodium Life Cycle in Hepatocyte with Varying Population

Indian Journal of Public Health Research & Development, 2019
Nagadevi Bala Nagaram, Suresh Rasapan
semanticscholar   +2 more sources

Antimalarial Agents Derived from Metal-Amodiaquine Complexes with Activity in Multiple Stages of the Plasmodium Life Cycle†.

Chemistry, 2023
Quinolines are excellent ligands for metal coordination and are deployed as drugs for malaria treatment. There is a growing body of evidence indicating that metal complexes can be conjugated with antimalarial quinolines to be used as chemical tools to ...
L. Colina-Vegas, Mariana da Cruz B. Silva, Caroline de Souza Pereira, Ariane Isis Barros, Joaquim Araújo Nobrega, M. Navarro, M. Rottmann, S. D’Alessandro, N. Basilico, Alzir Azevedo Batista, D. Moreira   +10 more
semanticscholar   +1 more source

Plasmodium Life Cycle-Stage Classification on Thick Blood Smear Microscopy Images using Deep Learning: A Contribution to Malaria Diagnosis

Symposium on Medical Information Processing and Analysis, 2023
Malaria is a life-threatening disease spread to humans through the bites of female Anopheles mosquitoes infected with Plasmodium parasite species. Prompt malaria diagnosis is recommended by WHO for all patients with suspected malaria before they are ...
F. A. S. Araujo, N. D. Colares, U. P. Carvalho, C. F. F. C. Filho, M. Costa   +4 more
semanticscholar   +1 more source

Melatonin effects on Plasmodium life cycle: new avenues for therapeutic approach.

Recent Patents on Endocrine, Metabolic & Immune Drug Discovery, 2012
Malaria remains a global health problem affecting more than 515 million people all over the world including Malaysia. It is on the rise, even within unknown regions that previous to this were free of malaria. Although malaria eradication programs carried out by vector control programs are still effective, anti-malarial drugs are also used extensively ...
V. Srinivasan, A. H. Ahmad, M. Mohamed, R. Zakaria   +3 more
semanticscholar   +4 more sources

Advancements and Challenges in Developing Malaria Vaccines: Targeting Multiple Stages of the Parasite Life Cycle.

ACS Infectious Diseases, 2023
Malaria, caused by Plasmodium species, remains a major global health concern, causing millions of deaths annually. While the introduction of the RTS,S vaccine has shown promise, there is a pressing need for more effective vaccines due to the emergence of
Rajneesh, Rahul Tiwari, V. K. Singh, Awnish Kumar, Rohit P. Gupta, A. K. Singh, Vibhav Gautam, Rajiv Ranjan Kumar   +7 more
semanticscholar   +1 more source

Mitochondrial apurinic/apyrimidinic endonuclease Apn1 is not critical for the completion of the Plasmodium berghei life cycle

DNA Repair, 2021
Mitochondrion is an essential organelle in malaria parasite and its DNA must be maintained for optimal function during its complex life cycle. Base excision repair is one of the major pathways by which this is achieved. Apurinic/apyrimidinic (AP) endonucleases are important components of this pathway as they create a nick at the 5'-phosphodiester bond ...
Sunil Kumar Narwal, Satish Mishra, Satish Mishra, Pratik Narain Srivastava   +3 more
openaire   +3 more sources

Life-Cycle of Plasmodium Relictum Var. Matutinum

The American Journal of Tropical Medicine and Hygiene, 1940
Summary and Conclusions 1.  Exoerythrocytic schizogony has been looked for in 18 cases of infection with Plasmodium relictum var. matutinum, and demonstrated in 9. It has been found both in blood-induced infections and those resulting from the bites of infected mosquitoes. 2.
openaire   +2 more sources

A dataset and benchmark for malaria life-cycle classification in thin blood smear images

Neural computing & applications (Print), 2021
Malaria microscopy, microscopic examination of stained blood slides to detect parasite Plasmodium, is considered to be a gold standard for detecting life-threatening disease malaria.
Qazi Ammar Arshad, Mohsen Ali, Saeed-Ul Hassan, Chen Chen, A. Imran, G. Rasul, Waqas Sultani   +6 more
semanticscholar   +1 more source