Results 81 to 90 of about 67,974 (216)

Plasmodium life cycle stage classification based quantification of malaria parasitaemia in thin blood smears [PDF]

Microscopy Research and Technique, 2018
AbstractVisual inspection for the quantification of malaria parasitaemiain (MP) and classification of life cycle stage are hard and time taking. Even though, automated techniques for the quantification of MP and their classification are reported in the literature. However, either reported techniques are imperfect or cannot deal with special issues such
Naveed Abbas, Tanzila Saba, Amjad Rehman, Zahid Mehmood, Hoshang kolivand, Mueen Uddin, Adeel Anjum   +6 more
openaire   +2 more sources

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

Genome-Wide Identification of the Target Genes of AP2-O, a Plasmodium AP2-Family Transcription Factor. [PDF]

PLoS Pathogens, 2015
Stage-specific transcription is a fundamental biological process in the life cycle of the Plasmodium parasite. Proteins containing the AP2 DNA-binding domain are responsible for stage-specific transcriptional regulation and belong to the only known ...
Izumi Kaneko, Shiroh Iwanaga, Tomomi Kato, Issei Kobayashi, Masao Yuda   +4 more
doaj   +1 more source

DNA-encoded nucleosome occupancy is associated with transcription levels in the human malaria parasite Plasmodium falciparum. [PDF]

, 2014
BackgroundIn eukaryotic organisms, packaging of DNA into nucleosomes controls gene expression by regulating access of the promoter to transcription factors.
Bunnik, Evelien M, Gill, Sarjeet S, Le Roch, Karine G, Lonardi, Stefano, Polishko, Anton, Ponts, Nadia, Prudhomme, Jacques   +6 more
core   +3 more sources

Solar Geoengineering Effects on Malaria Transmission Risk in South Asia Under G6sulfur Scenario

International Journal of Climatology, EarlyView.
Comparison of EIR (unit: No of infected bites per person per day) for each considered country in South Asia, under the considered scenarios, averaged over the period 2020–2090. A regression equation is shown for each country (for Bhutan EIRG = 0.1690 × 10−10 EIRS + 0.5968 × 10−12) to illustrate the projected trend.
Athar Hussain, Muhammad Ali Khan, Muhammad Shoaib   +2 more
wiley   +1 more source

Identification and characterization of a liver stage-specific promoter region of the malaria parasite Plasmodium. [PDF]

PLoS ONE, 2010
During the blood meal of a Plasmodium-infected mosquito, 10 to 100 parasites are inoculated into the skin and a proportion of these migrate via the bloodstream to the liver where they infect hepatocytes.
Susanne Helm, Christine Lehmann, Andreas Nagel, Rebecca R Stanway, Sebastian Horstmann, Manuel Llinas, Volker T Heussler   +6 more
doaj   +1 more source

Unveiling the Sugary Secrets of Plasmodium Parasites

Frontiers in Microbiology, 2021
Plasmodium parasites cause malaria disease, one of the leading global health burdens for humanity, infecting hundreds of millions of people each year.
Felix Goerdeler, Felix Goerdeler, Peter H. Seeberger, Peter H. Seeberger, Oren Moscovitz   +4 more
doaj   +1 more source

Characterization and gene expression analysis of the cir multi-gene family of plasmodium chabaudi chabaudi (AS) [PDF]

, 2012
Background: The pir genes comprise the largest multi-gene family in Plasmodium, with members found in P. vivax, P. knowlesi and the rodent malaria species.
Berriman, Matthew, Brugat, Thibaut, Böhme, Ulrike, Cunningham, Deirdre, Jackson, Andrew, Langhorne, Jean, Lawton, Jennifer, Otto, Thomas Dan, Pain, Arnab, Preiser, Peter, Reid, Adam James, Yan, Yam Xue   +11 more
core   +3 more sources

Long‐term impact of exposure to Royal Guard, a pyriproxyfen‐based bed net, on pyrethroid‐resistant malaria vectors from Cameroon using DNA‐based metabolic resistance markers

Pest Management Science, Volume 81, Issue 4, Page 2165-2180, April 2025.
We used recently detected P450 DNA‐based markers of pyrethroid resistance in both Anopheles funestus and Anopheles gambiae to demonstrate that although pyrethroid‐resistant mosquitoes have higher ability to survive and live longer after exposure to Royal Guard, this net significantly affects their lifespan, blood feeding ability and interestingly ...
Emilie S Ngongang‐Yipmo, Magellan Tchouakui, Benjamin D Menze, Riccado F Tiomela, Derrick Fofie, Vanessa B Ngannang‐Fezeu, Jean L Mugenzi, Flobert Njiokou, Charles S Wondji   +8 more
wiley   +1 more source

Design of Potential Antimalarial Agents Based on a Homology Model of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase

Proceedings, 2017
There currently exists a dire need for safe and inexpensive new antimalarial drugs, which are effective against multiple life cycle stages of Plasmodium falciparum, and act through mechanisms that differ from those of the available drugs to prevent drug ...
Caterina Pont, Nelson Alencar, Irene Sola, María Linares, Luca Di Palma, Carla Barbaraci, Cristina Sampedro, Jordi Juárez-Jiménez, Paloma Abad, Susana Pérez-Benavente, Jerónimo Lameira, José M. Bautista, F. Javier Luque, Diego Muñoz-Torrero   +13 more
doaj   +1 more source