Results 71 to 80 of about 28,686 (237)
Retinal Hemorrhages in Severe Non-cerebral Plasmodium vivax Malaria in an Adult [PDF]
Journal of Clinical and Diagnostic Research, 2015 Malaria is the most important parasitic diseases of humans and one of the leading causes of morbidity and mortality in tropical countries. Earlier Plasmodium vivax was considered as a benign infection, but now it is recognized as a cause of severe ...
Manoj Lakhotia +4 more
doaj +1 more source
Exploring Aspartate Transcarbamoylase: A Promising Broad‐Spectrum Target for Drug Development
ChemBioChem, Volume 26, Issue 7, April 1, 2025.Pyrimidine biosynthesis is a pivotal process shared by both eukaryotes and prokaryotes. This review examines the applications and advantages of a series of inhibitors specifically designed to target aspartate transcarbamylase within the de novo biosynthetic pathway of the malarial parasite.
Siyao Chen +8 more
wiley +1 more source
Insights into the invasion biology of Plasmodium vivax [PDF]
Frontiers in Cellular and Infection Microbiology, 2013 Plasmodium vivax is the most widely distributed human malaria parasite outside sub Sahara regions of Africa causing huge morbidity and occasionally being severe and fatal (Kochar et al., 2005; Tjitra et al., 2008). Invasion of host erythrocytes is essential for development of disease and the process varies greatly among different malaria parasites ...
Om P. Singh, Surendra K Prajapati
openaire +4 more sources
Epidemiology of Latency and Relapse in Plasmodium vivax Malaria [PDF]
arXiv, 2015 Malaria is a major contributor to health burdens throughout the regions where it is endemic. Historically, it was believed that there was limited morbidity and essentially no mortality associated with Plasmodium vivax; however, evidence from diverse settings now suggests that infections with P. vivax can be both severe and fatal.
arxiv
Circulating Growth Differentiation Factor 15 (GDF15) in Paediatric Disease: A Systematic Review
Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 2, April 2025.ABSTRACT Background Growth Differentiation Factor 15 (GDF15), a nonspecific inflammatory marker and member of the TGF‐β superfamily, has a well‐established role in both inflammation and metabolic modulation, but lacks a comprehensive paediatric literature review.
David W. Kronenberger +3 more
wiley +1 more source
PLoS Pathogens, 2019 Eukaryotes of the genus Plasmodium cause malaria, a parasitic disease responsible for substantial morbidity and mortality in humans. Yet, the nature and abundance of any viruses carried by these divergent eukaryotic parasites is unknown.
Justine Charon +9 more
doaj +1 more source
Molecular Plant Pathology, Volume 26, Issue 4, April 2025.The Sclerotinia sclerotiorum GPI‐anchored protein SsGP1 is recognised by plants as a PAMP in a BAK1‐dependent manner, thereby activating immune responses and enhancing disease resistance. ABSTRACT GPI‐anchored proteins are widely distributed in eukaryotic cells. However, their functions are still poorly understood in necrotrophic pathogenic fungi. Here,
Guangxing Miao +9 more
wiley +1 more source
ChemMedChem, Volume 20, Issue 6, March 15, 2025.The present study describes the synthesis and thorough investigation of 1,2,3‐triazole‐methyl‐menadione derivatives with particular emphasis on their electrochemical and physicochemical properties and their antiparasitic activities against Plasmodium falciparum and Schistosoma mansoni. Although less effective against P.
Baptiste Dupouy +8 more
wiley +1 more source
Severe Plasmodium vivax infection in Korea [PDF]
Malaria Journal, 2017 Although severe malaria by Plasmodium vivax has been increasingly reported, there are marked variations in the type and rate of the complications by geographic area. This is possibly because of the presence of concurrent falciparum malaria or bacteraemia, and of differences in underlying immune status among the infected subjects. Furthermore, published
Areum Durey +7 more
openaire +3 more sources
Brazilian Journal of Infectious Diseases, 2010 This report describes the development of hemolysis in eighteen glucose-6-phosphate dehydrogenase deficient patients treated for Plasmodium vivax malaria with chloroquine and primaquine.
Wilson M. Ramos Júnior +5 more
doaj