Results 71 to 80 of about 62,495 (267)

Targeted disruption of py235ebp-1: Invasion of erythrocytes by Plasmodium yoelii using an alternative Py235 erythrocyte binding protein [PDF]

open access: yes, 2011
Plasmodium yoelii YM asexual blood stage parasites express multiple members of the py235 gene family, part of the super-family of genes including those coding for Plasmodium vivax reticulocyte binding proteins and Plasmodium falciparum RH proteins.
Cunningham, Deirdre A.   +9 more
core   +4 more sources

The disappearance of malaria from Denmark, 1862–1900

open access: yesThe Economic History Review, EarlyView.
Abstract The reason for malaria's disappearance from northwestern Europe in the early twentieth century has long been discussed but remains an unresolved conundrum. This is partially due to a previous focus on the early modern era, and partially because various theories have never been tested against each other.
Mathias Mølbak Ingholt   +3 more
wiley   +1 more source

New Evidence of TLR4 and TLR9 Variants Influencing Parasitaemia and Symptoms of Plasmodium vivax Infection

open access: yesInternational Journal of Immunogenetics, EarlyView.
ABSTRACT Toll‐like receptors (TLRs) induce the production of pro‐inflammatory cytokines and regulate the immune response to Plasmodium vivax infection. Genetic variants of TLRs are associated with susceptibility and severity of malaria in different populations. This study aimed to evaluate the association between polymorphisms in TLR1, TLR4, TLR7, TLR8,
Mikaele Monik Rodrigues Inácio Silva   +8 more
wiley   +1 more source

Artificial intelligence‐powered microscopy: Transforming the landscape of parasitology

open access: yesJournal of Microscopy, EarlyView.
Abstract Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their complex life cycles. Despite major advancements in imaging and analysis, several challenges remain. These include the integration of interdisciplinary data; information derived from various model
Mariana De Niz   +4 more
wiley   +1 more source

Comparative Evaluation of Available Immune-Chromatographic Tests Used for Detection of Plasmodium Species, A Tertiary Care Hospital Experience

open access: yesPakistan Armed Forces Medical Journal
Objective: To test the sensitivity of locally available strips for the detection of Plasmodium Vivax and Plasmodium Falciparum species at a tertiary care hospital. Study Design: Cross-sectional study.
Nabila Rafique   +5 more
doaj   +1 more source

Towards Malaria Elimination: A Nationwide Case–Control Study to Assess Risk Factors for Severe Malaria‐Related Deaths in Brazil

open access: yesTropical Medicine &International Health, EarlyView.
ABSTRACT Objective The objective of this study is to describe malaria‐related deaths and assess their risk factors. Methods This is a case–control study using data from Brazil's Ministry of Health (2011–2020) on malaria‐related deaths (ICD‐10: B50‐B54). A probabilistic record linkage was performed to match epidemiological data (Sivep‐Malaria and Sinan)
Klauss K. S. Garcia   +10 more
wiley   +1 more source

Impact of NLRP1 Met1154Val and IL1B variants on gestational malaria: an unexplored role of NLRP1 in inflammasome activation by Plasmodium spp.

open access: yesThe Journal of Pathology, Volume 267, Issue 3, Page 304-314, November 2025.
Abstract We hypothesized that variants in inflammasome‐related genes could influence susceptibility to gestational malaria (GM). To test this, we conducted an association study in a cohort of pregnant women from a malaria‐endemic region in northern Brazil, assessing whether specific functional single nucleotide variants (SNVs) in inflammasome genes ...
Vinicius NC Leal   +8 more
wiley   +1 more source

Measuring ex vivo drug susceptibility in Plasmodium vivax isolates from Cambodia

open access: yesMalaria Journal, 2017
Background While intensive Plasmodium falciparum multidrug resistance surveillance continues in Cambodia, relatively little is known about Plasmodium vivax drug resistance in Cambodia or elsewhere. To investigate P.
Suwanna Chaorattanakawee   +19 more
doaj   +1 more source

An improved Plasmodium cynomolgi genome assembly reveals an unexpected methyltransferase gene expansion. [PDF]

open access: yes, 2017
Background: Plasmodium cynomolgi, a non-human primate malaria parasite species, has been an important model parasite since its discovery in 1907. Similarities in the biology of P.
Berriman, Matt   +7 more
core   +2 more sources

Reimagining Social Value to Consider the Environment: How Should We Judge the Magnitude of Benefits in Health Research?

open access: yesBioethics, Volume 39, Issue 9, Page 821-833, November 2025.
ABSTRACT Growing recognition of intersections between our health and the environment, healthcare systems and the environment, and health research and the environment has led bioethics scholars to advocate that the field readopt a broader perspective that considers nature.
Bridget Pratt, Rieke van der Graaf
wiley   +1 more source

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