Results 51 to 60 of about 1,516,482 (310)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Testing phenol formaldehyde composite insulation material for conservation purposes

open access: yesCeROArt : Conservation, Exposition, Restauration d'Objets d'Art, 2018
This investigation related to the degradation of phenol formaldehyde based electrical insulation materials in close mechanical contact with CZ108 brass in a Post Office Type 36 time transmitter, an electromechanical clock.
Tabea Rude
doaj   +1 more source

Constraining the atmospheric limb of the plastic cycle

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2021
Significance Microplastic particles and fibers generated from the breakdown of mismanaged waste are now so prevalent that they cycle through the earth in a manner akin to global biogeochemical cycles. In modeling the atmospheric limb of the plastic cycle,
J. Brahney   +6 more
semanticscholar   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Canaux anciens et puits récents : usages de l’eau d’irrigation, identité et territoire dans le Haouz (Maroc)

open access: yesDéveloppement Durable et Territoires, 2019
By associating an ethnography of contemporary practices and a diachronic approach, this article tries to show the co-construction over time of an irrigated soil and of a social group, in a locality in Marrakesh’s plain (Haouz).
Violaine Héritier-Salama
doaj   +1 more source

Plastic Memories of the Anthropocene

open access: yesMetacritic Journal for Comparative Studies and Theory, 2021
Plastic has become a ubiquitous material on planet Earth. I use Bennett’s term, thing-power, to analyse various aspects of plastic’s onto-materiality.
Daniel Clinci
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Safety assessment of the process Green Loop System, used to recycle polycyclohexylene dimethylene terephthalate glycol‐modified (PCTG) plates for use as food contact materials

open access: yesEFSA Journal, 2022
The EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP) assessed the safety of the recycling process Green Loop System (EU register number RECYC174), a closed and controlled product loop.
EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP)   +22 more
doaj   +1 more source

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