Results 71 to 80 of about 1,960,468 (279)
The effect of temperature distribution on a stress–strain state tube made of disperse-hardened aluminum alloy subjected to internal pressure was investigated.
Oleg Matvienko +2 more
doaj +1 more source
Limits to behavioural plasticity
Larissa T. Beumer, Thomas Mueller
openaire +2 more sources
Effect of various temperatures to liquid limit, plastic limit, and plasticity index of clays
This research aims to study the liquid limit, plastic limit, and plasticity index of soil samples treated with elevated temperatures. Liquid limit and plastic limit are physical properties of soils. Bentonite, kaolin, and Pasir Panjang samples were heated in an oven from room temperature up to 100 °C before the test.
Budijanto Widjaja +1 more
openaire +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Experience Formula of Shear Strength of the Weak Layer
The weak layers are the most important boundaries controlling rock mass stability.The engineering properties of the weak layer are controlled by the basic substance and environment conditions.The study shows that a good correlativity exists among shear ...
LIU Hong-li, SHI Yu-chuan, LIU Han-chao
doaj
Effect of pH value on boundary water content of red clay in Guilin and its mechanism
The liquid and plastic limits are the important factors to reflect the penetration resistance, anti-erosion and anti-shear of soils. The liquid ad plastic limits of the red clay in Guilin soaked in the acid and alkali solutions are tested to study its ...
LI Shan-mei 1,2, LIU Zhi-kui 1,2, MENG Jian-ping 1,2
doaj +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Influence of Inorganic Salts on Soils Liquid and Plastic Limits
This study focused on the influence of inorganic salts on soil liquid limit (LL) and plastic limit (PL). Sodium chloride, NaCl, potassium nitrate KNO3 and calcium sulphate, CaSO4 of various concentrations were added to two subsoils.
Ayininuola, G.M., Agbede, O.A.
doaj

