Results 81 to 90 of about 1,960,468 (279)
A robust prediction model for evaluation of plastic limit based on sieve # 200 passing material using gene expression programming. [PDF]
PLoS One, 2022 Nawaz MN +5 more
europepmc +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
A fully implicit multi-axial solution strategy for direct ratchet boundary evaluation : implementation and comparison [PDF]
, 2012 Ensuring sufficient safety against ratcheting is a fundamental requirement in pressure vessel design. However, determining the ratchet boundary using a full elastic plastic finite element analysis can be problematic and a number of direct methods have ...
Jappy, Alan +2 more
core +3 more sources
Plastic hepatocyte states limit liver cancer development
Nature CommunicationsThe liver has remarkable regenerative capacity owing to the boundless proliferative potential of hepatocytes. During liver injury, sustained regeneration must be balanced by mechanisms limiting overgrowth and tumorigenesis.
Lauren S. Strathearn +15 more
doaj +1 more source
Prediction of Consolidation Characteristics from Index Properties
E3S Web of Conferences, 2018 Compression index and coefficient of consolidation are two most important parameters in obtaining the consolidation characteristics of cohesive soil. Considerable time and effort are required to obtain these parameters from the oedometer test. Therefore,
Ng Kok Shien +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Collapse Scenarios of High-Rise Buildings Using Plastic Limit Analysis
Advances in Civil Engineering, 2009 The Twin Towers of the World Trade Center (WTC) in New York, USA collapsed on 11 September, 2001. The incident is regarded as the most severe disaster for high-rise buildings in history.
G. Liu, D. K. Liu, W. K. Chow
doaj +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
The limit states of polymetallic plates with piecewise elliptic contours
MATEC Web of Conferences, 2018 A unified approach to the study of plastic deformation of polymetallic isotropic plates with smooth and piecewise smooth support contours under the influence of static loads is developed.
Nemirovskii Yuri
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source