Results 41 to 50 of about 1,191,103 (227)

Gravin orchestrates protein kinase A and 2-adrenergic receptor signaling critical for synaptic plasticity and memory [PDF]

, 2012
A kinase-anchoring proteins (AKAPs) organize compartmentalized pools of protein kinase A (PKA) to enable localized signaling events within neurons. However, it is unclear which of the many expressed AKAPs in neurons target PKA to signaling complexes ...
Abel, T., Baillie, G.S., Canton, D.A., Day, J.P., Gelman, I.H., Grimes, Q., Guercio, L.A., Havekes, R., Huang, T., Luczak, V., Nie, T., Park, A.J., Scott, J.D.   +12 more
core   +2 more sources

Clusters of synaptic inputs on dendrites of layer 5 pyramidal cells in mouse visual cortex

eLife, 2016
The spatial organization of synaptic inputs on the dendritic tree of cortical neurons plays a major role for dendritic integration and neural computations, yet, remarkably little is known about it.
Onur Gökçe, Tobias Bonhoeffer, Volker Scheuss   +2 more
doaj   +1 more source

Plasticity

, 2020
Although the expression πλαστική τέχνη [plastic art] has Greek origins, the derivative term “plasticity” enters the European languages only in the Modern Age. The term has a double meaning: it indicates, at the same time, the art of manipulating a ductile substance and the ability to transform oneself to recreate formal qualities in response to ...
openaire   +3 more sources

Plasticity and Anxiety [PDF]

Neural Plasticity, 2007
Anxiety is a very broad behavioural trait, helping animals to cope with dangerous environmental situations. As anxiety is linked to other emotional processes and to cognitive functions such as learning and memory, it involves a number of cerebral structures and brain transmitter systems, thereby giving rise to a high degree of plasticity.
Georges Chapouthier, Patrice Venault
openaire   +3 more sources

IgSF21 promotes differentiation of inhibitory synapses via binding to neurexin2α

Nature Communications, 2017
Molecular mechanisms regulating the development of inhibitory synapses are poorly understood. Here the authors show that IgSF21 interacts with neurexin2α to induce presynaptic differentiation of inhibitory synapses, and that mice lacking IgSF21 exhibit ...
Yuko Tanabe, Yusuke Naito, Cristina Vasuta, Alfred Kihoon Lee, Youssouf Soumounou, Michael W. Linhoff, Hideto Takahashi   +6 more
doaj   +1 more source

Social maintenance masks induced aggression in zebrafish

Scientific Reports
Animal behavior is dynamically shaped by internal states and external social contexts. This study examines how internal states and social buffering influence aggression and social behavior.
Ashil Arroth Kuniyil, Muhammed Sinan Malik, Rahul Kizhakke Vellattu, Dhanusha Sivarajan, Gokul Krishna Thozhukkara Mannarapurayil, Fasna Pokkakillath Faisal, Nimisha Chathooth, Binu Ramachandran   +7 more
doaj   +1 more source

LRP4 is required for the olfactory association task in the piriform cortex

Cell & Bioscience, 2022
Background Low-density lipoprotein receptor-related protein 4 (LRP4) plays a critical role in the central nervous system (CNS), including hippocampal synaptic plasticity, maintenance of excitatory synaptic transmission, fear regulation, as well as long ...
Min Yan, Mingtao Xiong, Yongqiang Wu, Dong Lin, Peng Chen, Jiang Chen, Ziyang Liu, Hang Zhang, Dongyan Ren, Erkang Fei, Xinsheng Lai, Suqi Zou, Shunqi Wang   +12 more
doaj   +1 more source

Targeting CNS Neural Mechanisms of Gait in Stroke Neurorehabilitation

Brain Sciences, 2022
The central nervous system (CNS) control of human gait is complex, including descending cortical control, affective ascending neural pathways, interhemispheric communication, whole brain networks of functional connectivity, and neural interactions ...
Jessica P. McCabe, Svetlana Pundik, Janis J. Daly   +2 more
doaj   +1 more source

Control over stress induces plasticity of individual prefrontal cortical neurons: A conductance-based neural simulation [PDF]

, 2011
Behavioral control over stressful stimuli induces resilience to future conditions when control is lacking. The medial prefrontal cortex(mPFC) is a critically important brain region required for plasticity of stress resilience.
Andrew L. Varnell, Donald C. Cooper, Juan A. Varela, Jungang Wang   +3 more
core   +4 more sources

Long-term follow-up of the Bergen 4-day treatment for panic disorder during the COVID-19 pandemic

Cogent Psychology
The COVID-19 pandemic has necessitated essential modifications to the administration of psychotherapy for patients with panic disorder (PD) through the increased use of videoconferencing.
Kay Morten Hjelle, Thorstein Olsen Eide, Anders Lillevik Thorsen, Gerd Kvale, Kristen Hagen, Michael G. Wheaton, Thröstur Björgvinsson, Bjarne Hansen   +7 more
doaj   +1 more source