AMPA Receptor Phosphorylation and Synaptic Colocalization on Motor Neurons Drive Maladaptive Plasticity below Complete Spinal Cord Injury. [PDF]
Clinical spinal cord injury (SCI) is accompanied by comorbid peripheral injury in 47% of patients. Human and animal modeling data have shown that painful peripheral injuries undermine long-term recovery of locomotion through unknown mechanisms ...
Beattie, Michael S+7 more
core +1 more source
Direct and indirect selection on flowering time, water-use efficiency (WUE, δ (13)C), and WUE plasticity to drought in Arabidopsis thaliana. [PDF]
Flowering time and water-use efficiency (WUE) are two ecological traits that are important for plant drought response. To understand the evolutionary significance of natural genetic variation in flowering time, WUE, and WUE plasticity to drought in ...
Juenger, Thomas E+3 more
core +1 more source
Cannabinoid-induced actomyosin contractility shapes neuronal morphology and growth
Endocannabinoids are recently recognized regulators of brain development, but molecular effectors downstream of type-1 cannabinoid receptor (CB1R)-activation remain incompletely understood.
Alexandre B Roland+10 more
doaj +1 more source
Intraspecific variation in thermal acclimation and tolerance between populations of the winter ant, Prenolepis imparis. [PDF]
Thermal phenotypic plasticity, otherwise known as acclimation, plays an essential role in how organisms respond to short-term temperature changes.
Angilletta M. J.+6 more
core +1 more source
Balancing noise and plasticity in eukaryotic gene expression [PDF]
Coupling the control of expression stochasticity (noise) to the ability of expression change (plasticity) can alter gene function and influence adaptation.
Bajić, Djordje, Poyatos, Juan F.
core +4 more sources
Ancestral glycoprotein hormone-receptor pathway controls growth in C. elegans
In vertebrates, thyrostimulin is a highly conserved glycoprotein hormone that, besides thyroid stimulating hormone (TSH), is a potent ligand of the TSH receptor.
Signe Kenis+6 more
doaj +1 more source
Unsupervised learning of digit recognition using spike-timing-dependent plasticity
In order to understand how the mammalian neocortex is performing computations, two things are necessary; we need to have a good understanding of the available neuronal processing units and mechanisms, and we need to gain a better understanding of how ...
P. U. Diehl, Matthew Cook
semanticscholar +1 more source
Foraging environment determines the genetic architecture and evolutionary potential of trophic morphology in cichlid fishes [PDF]
Phenotypic plasticity allows organisms to change their phenotype in response to shifts in the environment. While a central topic in current discussions of evolutionary potential, a comprehensive understanding of the genetic underpinnings of plasticity is
Albertson, R. Craig+7 more
core +2 more sources
Plasticity and dystonia: a hypothesis shrouded in variability. [PDF]
Studying plasticity mechanisms with Professor John Rothwell was a shared highlight of our careers. In this article, we discuss non-invasive brain stimulation techniques which aim to induce and quantify plasticity, the mechanisms and nature of their ...
A Albanese+52 more
core +1 more source
Combining optogenetics, behavioral modelling and neural population analysis, the authors show in mice that during fear-related freezing the olfactory bulb transmits 4 Hz breathing rhythm to the prefrontal cortex where this oscillation organizes local ...
Sophie Bagur+8 more
doaj +1 more source