Results 91 to 100 of about 1,085,462 (251)

Comparative finite element analysis of a novel distal tibiofibular locking plate versus conventional fixation methods for Tillaux-Chaput fractures

Frontiers in Bioengineering and Biotechnology
ObjectiveTillaux-Chaput fractures are avulsion fractures involving the tibial insertion of the anterior inferior tibiofibular ligament. Inadequate fixation may result in distal tibiofibular syndesmotic instability and post-traumatic ankle arthritis ...
Xiunian Hu, Fake Liao, Wutang Que, Huahui Huang, Han Li, Hui Liu, Weibin Lan, Rijiang Chen   +7 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Management of comminuted mid-shaft clavicular fractures: Comparison between dual-plate fixation treatment and single-plate fixation

Journal of Orthopaedic Surgery, 2020
Background: We consider dual-plate fixation to improve construct rigidity in cases with fracture complexity. The purpose of this study is to compare the rate of nonunion, prognosis, and complications at 6–12 months for surgically treated acute mid-shaft ...
Yunqiang Zhuang, Yadi Zhang, Long Zhou, Jun Zhang, Gangqiang Jiang, Ji Wu   +5 more
doaj   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Biomechanical comparison of locking plate and pin-tension band wiring fixation for 3D-printed canine patellar fracture repair

Frontiers in Veterinary Science
IntroductionThe conventional pin and tension band wiring (TBW) technique remains the standard for fixation, but is frequently associated with complications such as wire breakage, loosening, and delayed healing in patellar fracture. Locking plate fixation
Seung-Gi Jung, Hwi-Yool Kim
doaj   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Plate dynamics, mantle structure and tectonic evolution of the Caribbean region [PDF]

, 2013
The northeastern Caribbean exhibits high deformation and is fragmented by several faults into smaller tectonic blocks. One of these faults was the site of the catastrophic 12th of January 2010 earthquake. In this thesis I aim to constrain the main forces
How plate tearing and slabs drive reorganization of the N Caribbean plate boundary, Tectonophysics, van Benthem, S.A.C.   +2 more
core  

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Biomechanical comparison of fixation systems in posterior wall fracture of acetabular by finite element analysis

Computer Assisted Surgery, 2016
Background: The use of reconstruction plates and lag screws has been recommended for fractures to the posterior wall of the acetabulum. However, little information about the rigidity of recommended forms of fracture fixation is available.
Jianyin Lei, Haibo Liu, Zhiqiang Li, Zhihua Wang, Ximing Liu, Longmao Zhao   +5 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source