Results 81 to 90 of about 1,085,462 (251)

Biomechanics of common fixation devices for first tarsometatarsal joint fusion—a comparative study with synthetic bones

Journal of Orthopaedic Surgery and Research, 2018
Background Hallux valgus disease is a common deformity of the forefoot. There are currently more than 100 surgical approaches for operative treatment. Because hypermobility of the first tarsometatarsal joint is considered to be causal for hallux valgus ...
Rene Burchard, Robin Massa, Christian Soost, Wolfgang Richter, Gerhard Dietrich, Arne Ohrndorf, Hans-Jürgen Christ, Claus-Peter Fritzen, Jan Adriaan Graw, Jan Schmitt   +9 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Nitrogen Fixation and Translocation in Sugarcane [PDF]

, 2008
World sugarcane production is increasing rapidly as a biofuel. In some areas in Brazil, sugarcane has been grown continually over very long periods without N fertiliser inputs. Therefore, the occurrence of N fixation has been suspected.
Kuni Sueyoshi, Takashi Sato, Takuji Ohyama, Yasuhiro Nakanishi, Atsushi Momose, Norikuni Ohtake, Shoichiro Akao   +6 more
core  

Locking Plate with Cerclage Wiring Versus Hook Plate Fixation for Unstable Distal Clavicle Fractures: Is There Still a Role for Hook Plates?

Medicina
Background and Objectives: Hook plate fixation has been widely used for unstable distal clavicle fractures, but concerns remain regarding implant-related complications and the need for secondary removal. Locking plate fixation with supplementary cerclage
Hyun Seok Song, Hyungsuk Kim
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Rim plate fixation for a rare fracture pattern of the lateral femoral condyle: A case report

Osteochondral fractures of the lateral femoral condyle caused by lateral patella dislocation have been rarely reported. The AO/OTA Classification is not suitable for this uncommon injury.
Hanrong Xu, Yinjiang Lu, Ding Xu, Jiong Lin   +3 more
core   +1 more source

PERBANDINGAN FIKSASI TULANG CALVARIA MENGGUNAKAN ABSORBABLE PLATE FIXATION DENGAN ABSORBABLE SUTURE FIXATION PADA PASIEN SYNDROMIC CRANIOSYNOSTOSIS [PDF]

, 2019
Latar Belakang Teknik pembedahan pada malformasi kraniofasial terdiri dari osteotomi, suturektomi, dan reposisi dari regio yang mengalami kelainan. Stabilisasi dari reposisi segmen tulang paling baik dilakukan dengan fiksasi benang, pemasangan wire ...
Arif Tri Prasetyo, NIM011418246303
core   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Nitrogen fixation and nitrogenase activity of Azotobacter chroococcum [PDF]

, 1974
The purpose of the present investigation was to study the effect of some chemical, physical and biological factors on growth, efficiency of nitrogen fixation and nitrogenase activity of Azotobacter chroococcum.From biochemical studies with cell-free ...
Brotonegoro, S.
core